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Human KLF4/EZF/GKLF ORF/cDNA clone-Lentivirus particle (NM_001314052.2)
Cat. No.: vGMLV002425
Pre-made Human KLF4/EZF/GKLF Lentiviral expression plasmid for KLF4 lentivirus packaging, KLF4 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.
The GM Vector Core (GMVC) specializes in custom lentivirus development and offers a range of lentivirus manufacturing solutions, leveraging state-of-the-art processes. Learn more about our services.
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MSDS
| Catalog No. | Product Name | lentivirus Grade | lentivirus quantity |
|---|---|---|---|
| vGMLV002425 | Human KLF4 Lentivirus particle | Pilot Grade | 1.0E+8TU |
| 5.0E+8TU | |||
| 1.0E+9TU | |||
| Research Grade | 1.0E+8TU | ||
| 5.0E+8TU | |||
| 1.0E+9TU | |||
| GMP-like Grade | inquiry | ||
| GMP Grade | inquiry |
Product Description
| Catalog ID | vGMLV002425 |
| Gene Name | KLF4 |
| Accession Number | NM_001314052.2 |
| Gene ID | 9314 |
| Species | Human |
| Product Type | Lentivirus particle (overexpression) |
| Insert Length | 1542 bp |
| Gene Alias | EZF,GKLF |
| Fluorescent Reporter | ZsGreen |
| Mammalian Cell Selection | Puromyocin |
| Fusion Tag | 3xflag (C-Terminal) |
| Promoter | CMV |
| Resistance | Amplicin |
| ORF Nucleotide Sequence | ATGAGGCAGCCACCTGGCGAGTCTGACATGGCTGTCAGCGACGCGCTGCTCCCATCTTTCTCCACGTTCGCGTCTGGCCCGGCGGGAAGGGAGAAGACACTGCGTCAAGCAGGTGCCCCGAATAACCGCTGGCGGGAGGAGCTCTCCCACATGAAGCGACTTCCCCCAGTGCTTCCCGGCCGCCCCTATGACCTGGCGGCGGCGACCGTGGCCACAGACCTGGAGAGCGGCGGAGCCGGTGCGGCTTGCGGCGGTAGCAACCTGGCGCCCCTACCTCGGAGAGAGACCGAGGAGTTCAACGATCTCCTGGACCTGGACTTTATTCTCTCCAATTCGCTGACCCATCCTCCGGAGTCAGTGGCCGCCACCGTGTCCTCGTCAGCGTCAGCCTCCTCTTCGTCGTCGCCGTCGAGCAGCGGCCCTGCCAGCGCGCCCTCCACCTGCAGCTTCACCTATCCGATCCGGGCCGGGAACGACCCGGGCGTGGCGCCGGGCGGCACGGGCGGAGGCCTCCTCTATGGCAGGGAGTCCGCTCCCCCTCCGACGGCTCCCTTCAACCTGGCGGACATCAACGACGTGAGCCCCTCGGGCGGCTTCGTGGCCGAGCTCCTGCGGCCAGAATTGGACCCGGTGTACATTCCGCCGCAGCAGCCGCAGCCGCCAGGTGGCGGGCTGATGGGCAAGTTCGTGCTGAAGGCGTCGCTGAGCGCCCCTGGCAGCGAGTACGGCAGCCCGTCGGTCATCAGCGTCAGCAAAGGCAGCCCTGACGGCAGCCACCCGGTGGTGGTGGCGCCCTACAACGGCGGGCCGCCGCGCACGTGCCCCAAGATCAAGCAGGAGGCGGTCTCTTCGTGCACCCACTTGGGCGCTGGACCCCCTCTCAGCAATGGCCACCGGCCGGCTGCACACGACTTCCCCCTGGGGCGGCAGCTCCCCAGCAGGACTACCCCGACCCTGGGTCTTGAGGAAGTGCTGAGCAGCAGGGACTGTCACCCTGCCCTGCCGCTTCCTCCCGGCTTCCATCCCCACCCGGGGCCCAATTACCCATCCTTCCTGCCCGATCAGATGCAGCCGCAAGTCCCGCCGCTCCATTACCAAGGTCAGTCCCGGGGATTTGTAGCTCGGGCTGGGGAGCCCTGTGTGTGCTGGCCCCACTTCGGGACACACGGGATGATGCTCACCCCACCTTCTTCACCCCTAGAGCTCATGCCACCCGGTTCCTGCATGCCAGAGGAGCCCAAGCCAAAGAGGGGAAGACGATCGTGGCCCCGGAAAAGGACCGCCACCCACACTTGTGATTACGCGGGCTGCGGCAAAACCTACACAAAGAGTTCCCATCTCAAGGCACACCTGCGAACCCACACAGGTGAGAAACCTTACCACTGTGACTGGGACGGCTGTGGATGGAAATTCGCCCGCTCAGATGAACTGACCAGGCACTACCGTAAACACACGGGGCACCGCCCGTTCCAGTGCCAAAAATGCGACCGAGCATTTTCCAGGTCGGACCACCTCGCCTTACACATGAAGAGGCATTTTTAA |
| ORF Protein Sequence | MRQPPGESDMAVSDALLPSFSTFASGPAGREKTLRQAGAPNNRWREELSHMKRLPPVLPGRPYDLAAATVATDLESGGAGAACGGSNLAPLPRRETEEFNDLLDLDFILSNSLTHPPESVAATVSSSASASSSSSPSSSGPASAPSTCSFTYPIRAGNDPGVAPGGTGGGLLYGRESAPPPTAPFNLADINDVSPSGGFVAELLRPELDPVYIPPQQPQPPGGGLMGKFVLKASLSAPGSEYGSPSVISVSKGSPDGSHPVVVAPYNGGPPRTCPKIKQEAVSSCTHLGAGPPLSNGHRPAAHDFPLGRQLPSRTTPTLGLEEVLSSRDCHPALPLPPGFHPHPGPNYPSFLPDQMQPQVPPLHYQGQSRGFVARAGEPCVCWPHFGTHGMMLTPPSSPLELMPPGSCMPEEPKPKRGRRSWPRKRTATHTCDYAGCGKTYTKSSHLKAHLRTHTGEKPYHCDWDGCGWKFARSDELTRHYRKHTGHRPFQCQKCDRAFSRSDHLALHMKRHF |
Reference
Data / case study
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Associated products
| Category | Cat No. | Products Name |
|---|---|---|
| Target Antibody | GM-Tg-g-T81916-Ab | Anti-KLF4 monoclonal antibody |
| Target Antigen | GM-Tg-g-T81916-Ag | KLF4 protein |
| ORF Viral Vector | pGMLV000247 | Human KLF4 Lentivirus plasmid |
| ORF Viral Vector | pGMLV002172 | Human KLF4 Lentivirus plasmid |
| ORF Viral Vector | pGMLV002425 | Human KLF4 Lentivirus plasmid |
| ORF Viral Vector | pGMAD000164 | Human KLF4 Adenovirus plasmid |
| ORF Viral Vector | pGMAD000806 | Human KLF4 Adenovirus plasmid |
| ORF Viral Vector | pGMAD001331 | Human KLF4 Adenovirus plasmid |
| ORF Viral Vector | pGMPC001122 | Human KLF4 Mammalian (Non-Viral Vector) plasmid |
| ORF Viral Vector | vGMLV000247 | Human KLF4 Lentivirus particle |
| ORF Viral Vector | vGMLV002172 | Human KLF4 Lentivirus particle |
| ORF Viral Vector | vGMLV002425 | Human KLF4 Lentivirus particle |
| ORF Viral Vector | vGMAD000164 | Human KLF4 Adenovirus particle |
| ORF Viral Vector | vGMAD000806 | Human KLF4 Adenovirus particle |
| ORF Viral Vector | vGMAD001331 | Human KLF4 Adenovirus particle |
Target information
| Target ID | GM-T81916 |
| Target Name | KLF4 |
|
Gene Group Identifier （Target Gene ID in Homo species) |
9314 |
| Gene ID |
100054047 (Equus caballus), 100379626 (Felis catus), 114505 (Rattus norvegicus), 16600 (Mus musculus) 481657 (Canis lupus familiaris), 520842 (Bos taurus), 711169 (Macaca mulatta), 9314 (Homo sapiens) |
| Gene Symbols & Synonyms | KLF4,Klf4,GKLF,EZF,Zie,Gklf |
| Target Alternative Names | EZF,Epithelial zinc finger protein EZF,GKLF,Gklf,Gut-enriched krueppel-like factor,KLF4,Klf4,Krueppel-like factor 4,Zie |
| Uniprot Accession |
O43474,Q60793
Additional SwissProt Accessions: Q60793,O43474 |
| Uniprot Entry Name | |
| Protein Sub-location | Introcelluar Protein |
| Category | Therapeutics Target |
| Disease | cancer |
| Disease from KEGG | Signaling pathways regulating pluripotency of stem cells, Chemical carcinogenesis - receptor activation |
| Gene Ensembl | ENSECAG00000010613, ENSMUSG00000003032, ENSCAFG00845011624, ENSBTAG00000020355, ENSMMUG00000006088, ENSG00000136826 |
| Target Classification | Tumor-associated antigen (TAA) |
About GMVC
GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.