Recombinant multi-species KLF4 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine KLF4 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a protein that belongs to the Kruppel family of transcription factors. The encoded zinc finger protein is required for normal development of the barrier function of skin. The encoded protein is thought to control the G1-to-S transition of the cell cycle following DNA damage by mediating the tumor suppressor gene p53. Mice lacking this gene have a normal appearance but lose weight rapidly, and die shortly after birth due to fluid evaporation resulting from compromised epidermal barrier function. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2015]
The Alternative Names of target: EZF,Epithelial zinc finger protein EZF,GKLF,Gklf,Gut-enriched krueppel-like factor,KLF4,Klf4,Krueppel-like factor 4,Zie

Target products collectionGo to KLF4 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T81916-Ag-1/ GM-Tg-hg-T81916-Ag-2 Human KLF4 protein Human
GM-Tg-rg-T81916-Ag-1/ GM-Tg-rg-T81916-Ag-2 Rat KLF4 protein Rat
GM-Tg-mg-T81916-Ag-1/ GM-Tg-mg-T81916-Ag-2 Mouse KLF4 protein Mouse
GM-Tg-cynog-T81916-Ag-1/ GM-Tg-cynog-T81916-Ag-2 Cynomolgus/Rhesus macaque KLF4 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T81916-Ag-1/ GM-Tg-felg-T81916-Ag-2 Feline KLF4 protein Feline
GM-Tg-cang-T81916-Ag-1/ GM-Tg-cang-T81916-Ag-2 Canine KLF4 protein Canine
GM-Tg-bovg-T81916-Ag-1/ GM-Tg-bovg-T81916-Ag-2 Bovine KLF4 protein Bovine
GM-Tg-equg-T81916-Ag-1/ GM-Tg-equg-T81916-Ag-2 Equine KLF4 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T81916-Ag-1/ GM-Tg-hg-T81916-Ag-2; GM-Tg-rg-T81916-Ag-1/ GM-Tg-rg-T81916-Ag-2;
GM-Tg-mg-T81916-Ag-1/ GM-Tg-mg-T81916-Ag-2; GM-Tg-cynog-T81916-Ag-1/ GM-Tg-cynog-T81916-Ag-2;
GM-Tg-felg-T81916-Ag-1/ GM-Tg-felg-T81916-Ag-2; GM-Tg-cang-T81916-Ag-1/ GM-Tg-cang-T81916-Ag-2;
GM-Tg-bovg-T81916-Ag-1/ GM-Tg-bovg-T81916-Ag-2; GM-Tg-equg-T81916-Ag-1/ GM-Tg-equg-T81916-Ag-2
Products Name KLF4 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name KLF4
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine KLF4 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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