Explore RSPO3 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Secreted Protein/Potential Cytokines.
This gene belongs to the R-spondin family. The encoded protein plays a role in the regulation of Wnt (wingless-type MMTV integration site family)/beta-catenin and Wnt/planar cell polarity (PCP) signaling pathways, which are involved in development, cell growth and disease pathogenesis. Genome-wide association studies suggest a correlation of this gene with bone mineral density and risk of fracture. This gene may be involved in tumor development. [provided by RefSeq, Jul 2013]
| Target ID |
GM-T79162
|
| Target Name |
RSPO3
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
84870
|
| Gene ID |
100067377 (Equus caballus), 101085635 (Felis catus), 476287 (Canis lupus familiaris), 498997 (Rattus norvegicus)
534650 (Bos taurus), 712288 (Macaca mulatta), 72780 (Mus musculus), 84870 (Homo sapiens)
|
| Target Alternative Names |
RSPO3,Rspo3,RGD1563246,Thsd2,Cristin1,2810459H04Rik,PWTSR,THSD2,CRISTIN1
|
| Uniprot Accession |
Q1RMU1,Q2TJ95,Q9BXY4
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Therapeutics Target, INN Index
|
| Disease |
|
| Disease from KEGG |
Wnt signaling pathway
|
| Gene Ensembl |
ENSECAG00000020203, ENSBTAG00000008121, ENSMMUG00000015355, ENSMUSG00000019880, ENSG00000146374
|
| Target Classification |
|
Pre-made viral vector of RSPO3 cDNA Clones/ORF Plasmid
RSPO3 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo84870 | Pre-made Human RSPO3/PWTSR/THSD2 siRNA oligo Duplex | 84870 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo498997 | Pre-made Rat Rspo3/RGD1563246 siRNA oligo Duplex | 498997 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo72780 | Pre-made Mouse Rspo3/Thsd2/Cristin1 siRNA oligo Duplex | 72780 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo712288 | Pre-made Cynomolgus/Rhesus macaque RSPO3 siRNA oligo Duplex | 712288 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101085635 | Pre-made Cat/Feline RSPO3 siRNA oligo Duplex | 101085635 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo476287 | Pre-made Dog/Canine RSPO3 siRNA oligo Duplex | 476287 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo534650 | Pre-made Bovines/Cattle RSPO3 siRNA oligo Duplex | 534650 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100067377 | Pre-made Equine/Horse RSPO3 siRNA oligo Duplex | 100067377 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
RSPO3 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T79162-Ab | Human | Anti-Human RSPO3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T79162-Ab | Rat | Anti-Rat RSPO3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T79162-Ab | Mouse | Anti-Mouse RSPO3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T79162-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque RSPO3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T79162-Ab | Cat/Feline | Anti-Cat/Feline RSPO3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T79162-Ab | Dog/Canine | Anti-Dog/Canine RSPO3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T79162-Ab | Bovines/Cattle | Anti-Bovines/Cattle RSPO3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T79162-Ab | Equine/Horse | Anti-Equine/Horse RSPO3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
RSPO3 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T79162-Ag | Human | Human RSPO3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T79162-Ag | Rat | Rat RSPO3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T79162-Ag | Mouse | Mouse RSPO3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T79162-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque RSPO3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T79162-Ag | Cat/Feline | Cat/Feline RSPO3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T79162-Ag | Dog/Canine | Dog/Canine RSPO3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T79162-Ag | Bovines/Cattle | Bovines/Cattle RSPO3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T79162-Ag | Equine/Horse | Equine/Horse RSPO3 recombinant protein | Mammalian cell | Detail |
