Recombinant multi-species RSPO3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine RSPO3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene belongs to the R-spondin family. The encoded protein plays a role in the regulation of Wnt (wingless-type MMTV integration site family)/beta-catenin and Wnt/planar cell polarity (PCP) signaling pathways, which are involved in development, cell growth and disease pathogenesis. Genome-wide association studies suggest a correlation of this gene with bone mineral density and risk of fracture. This gene may be involved in tumor development. [provided by RefSeq, Jul 2013]
The Alternative Names of target: 2810459H04Rik,CRISTIN1,Cristin1,PWTSR,Protein with TSP type-1 repeat (hPWTSR),R-spondin-3,RGD1563246,RSPO3,Roof plate-specific spondin-3 (hRspo3),Rspo3,THSD2,Thrombospondin type-1 domain-containing protein 2,Thsd2

Target products collectionGo to RSPO3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T79162-Ag-1/ GM-Tg-hg-T79162-Ag-2 Human RSPO3 protein Human
GM-Tg-rg-T79162-Ag-1/ GM-Tg-rg-T79162-Ag-2 Rat RSPO3 protein Rat
GM-Tg-mg-T79162-Ag-1/ GM-Tg-mg-T79162-Ag-2 Mouse RSPO3 protein Mouse
GM-Tg-cynog-T79162-Ag-1/ GM-Tg-cynog-T79162-Ag-2 Cynomolgus/Rhesus macaque RSPO3 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T79162-Ag-1/ GM-Tg-felg-T79162-Ag-2 Feline RSPO3 protein Feline
GM-Tg-cang-T79162-Ag-1/ GM-Tg-cang-T79162-Ag-2 Canine RSPO3 protein Canine
GM-Tg-bovg-T79162-Ag-1/ GM-Tg-bovg-T79162-Ag-2 Bovine RSPO3 protein Bovine
GM-Tg-equg-T79162-Ag-1/ GM-Tg-equg-T79162-Ag-2 Equine RSPO3 protein Equine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T79162-Ag-1/ GM-Tg-hg-T79162-Ag-2; GM-Tg-rg-T79162-Ag-1/ GM-Tg-rg-T79162-Ag-2;
GM-Tg-mg-T79162-Ag-1/ GM-Tg-mg-T79162-Ag-2; GM-Tg-cynog-T79162-Ag-1/ GM-Tg-cynog-T79162-Ag-2;
GM-Tg-felg-T79162-Ag-1/ GM-Tg-felg-T79162-Ag-2; GM-Tg-cang-T79162-Ag-1/ GM-Tg-cang-T79162-Ag-2;
GM-Tg-bovg-T79162-Ag-1/ GM-Tg-bovg-T79162-Ag-2; GM-Tg-equg-T79162-Ag-1/ GM-Tg-equg-T79162-Ag-2
Products Name RSPO3 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name RSPO3
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine RSPO3 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.