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Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a member of the kallikrein subfamily of serine proteases. These enzymes have diverse physiological functions and many kallikrein genes are biomarkers for cancer. The encoded protein has chymotrypsin-like activity and plays a role in the proteolysis of intercellular cohesive structures that precedes desquamation, the shedding of the outermost layer of the epidermis. The encoded protein may play a role in cancer invasion and metastasis, and increased expression of this gene is associated with unfavorable prognosis and progression of several types of cancer. Polymorphisms in this gene may play a role in the development of atopic dermatitis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, which is one of fifteen kallikrein subfamily members located in a gene cluster on chromosome 19. [provided by RefSeq, May 2011]
| Target ID |
GM-T79155
|
| Target Name |
KLK7
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
5650
|
| Gene ID |
100146194 (Equus caballus), 101088894 (Felis catus), 23993 (Mus musculus), 292852 (Rattus norvegicus) 506380 (Bos taurus), 5650 (Homo sapiens), 611780 (Canis lupus familiaris), 722683 (Macaca mulatta)
|
| Target Alternative Names |
KLK7,KLND,Kallikrein-7,Klk7,PRSS6,Prss6,SCCE,Serine protease 6,Stratum corneum chymotryptic enzyme (hSCCE),hK7
|
| Uniprot Accession |
Q91VE3,P49862
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Therapeutics Target
|
| Disease |
Lung Cancer
|
| Gene Ensembl |
ENSECAG00000031882, ENSMUSG00000030713, ENSBTAG00000030483, ENSG00000169035, ENSCAFG00845015235
|
Pre-made viral vector of KLK7 cDNA Clones/ORF Plasmid
KLK7 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo5650 | Pre-made Human KLK7/hK7/SCCE siRNA oligo Duplex | 5650 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo292852 | Pre-made Rat Klk7 siRNA oligo Duplex | 292852 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo23993 | Pre-made Mouse Klk7/SCCE/Prss6 siRNA oligo Duplex | 23993 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo722683 | Pre-made Cynomolgus/Rhesus macaque KLK7 siRNA oligo Duplex | 722683 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101088894 | Pre-made Cat/Feline KLK7 siRNA oligo Duplex | 101088894 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo611780 | Pre-made Dog/Canine KLK7 siRNA oligo Duplex | 611780 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo506380 | Pre-made Bovines/Cattle KLK7/KLND siRNA oligo Duplex | 506380 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100146194 | Pre-made Equine/Horse KLK7 siRNA oligo Duplex | 100146194 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
KLK7 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T79155-Ab | Human | Anti-Human KLK7 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T79155-Ab | Rat | Anti-Rat KLK7 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T79155-Ab | Mouse | Anti-Mouse KLK7 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T79155-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque KLK7 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T79155-Ab | Cat/Feline | Anti-Cat/Feline KLK7 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T79155-Ab | Dog/Canine | Anti-Dog/Canine KLK7 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T79155-Ab | Bovines/Cattle | Anti-Bovines/Cattle KLK7 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T79155-Ab | Equine/Horse | Anti-Equine/Horse KLK7 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
KLK7 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T79155-Ag | Human | Human KLK7 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T79155-Ag | Rat | Rat KLK7 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T79155-Ag | Mouse | Mouse KLK7 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T79155-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque KLK7 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T79155-Ag | Cat/Feline | Cat/Feline KLK7 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T79155-Ag | Dog/Canine | Dog/Canine KLK7 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T79155-Ag | Bovines/Cattle | Bovines/Cattle KLK7 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T79155-Ag | Equine/Horse | Equine/Horse KLK7 recombinant protein | Mammalian cell | Detail |