Recombinant multi-species KLK7 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine KLK7 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the kallikrein subfamily of serine proteases. These enzymes have diverse physiological functions and many kallikrein genes are biomarkers for cancer. The encoded protein has chymotrypsin-like activity and plays a role in the proteolysis of intercellular cohesive structures that precedes desquamation, the shedding of the outermost layer of the epidermis. The encoded protein may play a role in cancer invasion and metastasis, and increased expression of this gene is associated with unfavorable prognosis and progression of several types of cancer. Polymorphisms in this gene may play a role in the development of atopic dermatitis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, which is one of fifteen kallikrein subfamily members located in a gene cluster on chromosome 19. [provided by RefSeq, May 2011]
The Alternative Names of target: KLK7,KLND,Kallikrein-7,Klk7,PRSS6,Prss6,SCCE,Serine protease 6,Stratum corneum chymotryptic enzyme (hSCCE),hK7

Target products collectionGo to KLK7 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T79155-Ag-1/ GM-Tg-hg-T79155-Ag-2 Human KLK7 protein Human
GM-Tg-rg-T79155-Ag-1/ GM-Tg-rg-T79155-Ag-2 Rat KLK7 protein Rat
GM-Tg-mg-T79155-Ag-1/ GM-Tg-mg-T79155-Ag-2 Mouse KLK7 protein Mouse
GM-Tg-cynog-T79155-Ag-1/ GM-Tg-cynog-T79155-Ag-2 Cynomolgus/Rhesus macaque KLK7 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T79155-Ag-1/ GM-Tg-felg-T79155-Ag-2 Feline KLK7 protein Feline
GM-Tg-cang-T79155-Ag-1/ GM-Tg-cang-T79155-Ag-2 Canine KLK7 protein Canine
GM-Tg-bovg-T79155-Ag-1/ GM-Tg-bovg-T79155-Ag-2 Bovine KLK7 protein Bovine
GM-Tg-equg-T79155-Ag-1/ GM-Tg-equg-T79155-Ag-2 Equine KLK7 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T79155-Ag-1/ GM-Tg-hg-T79155-Ag-2; GM-Tg-rg-T79155-Ag-1/ GM-Tg-rg-T79155-Ag-2;
GM-Tg-mg-T79155-Ag-1/ GM-Tg-mg-T79155-Ag-2; GM-Tg-cynog-T79155-Ag-1/ GM-Tg-cynog-T79155-Ag-2;
GM-Tg-felg-T79155-Ag-1/ GM-Tg-felg-T79155-Ag-2; GM-Tg-cang-T79155-Ag-1/ GM-Tg-cang-T79155-Ag-2;
GM-Tg-bovg-T79155-Ag-1/ GM-Tg-bovg-T79155-Ag-2; GM-Tg-equg-T79155-Ag-1/ GM-Tg-equg-T79155-Ag-2
Products Name KLK7 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name KLK7
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine KLK7 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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