Explore IGFBP2 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Secreted Protein/Potential Cytokines.
The protein encoded by this gene is one of six similar proteins that bind insulin-like growth factors I and II (IGF-I and IGF-II). The encoded protein can be secreted into the bloodstream, where it binds IGF-I and IGF-II with high affinity, or it can remain intracellular, interacting with many different ligands. High expression levels of this protein promote the growth of several types of tumors and may be predictive of the chances of recovery of the patient. Several transcript variants, one encoding a secreted isoform and the others encoding nonsecreted isoforms, have been found for this gene. [provided by RefSeq, Sep 2015]
| Target ID |
GM-T64268
|
| Target Name |
IGFBP2
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
3485
|
| Gene ID |
100034061 (Equus caballus), 101088426 (Felis catus), 16008 (Mus musculus), 25662 (Rattus norvegicus) 282260 (Bos taurus), 3485 (Homo sapiens), 488516 (Canis lupus familiaris), 696214 (Macaca mulatta)
|
| Target Alternative Names |
BRL-BP,IBP-2,IBP2,IGF-BP53,IGF-binding protein 2,IGFBP-2,IGFBP2,ILGFBPA,Igfbp-2,Igfbp2,Insulin-like growth factor-binding protein 2,mIGFBP-2
|
| Uniprot Accession |
P47877,P12843,P13384,P18065
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Therapeutics Target, Immuno-oncology Target, Cytokine Target
|
| Disease |
cancer, Ovary Cancer, Dent disease
|
| Gene Ensembl |
ENSECAG00000035279, ENSMUSG00000039323, ENSBTAG00000005596, ENSG00000115457, ENSCAFG00845024863, ENSMMUG00000054183
|
| Target Classification |
Checkpoint-Immuno Oncology
|
Pre-made viral vector of IGFBP2 cDNA Clones/ORF Plasmid
IGFBP2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3485 | Pre-made Human IGFBP2/IBP2/IGF-BP53 siRNA oligo Duplex | 3485 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25662 | Pre-made Rat Igfbp2/IBP-2/BRL-BP siRNA oligo Duplex | 25662 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo16008 | Pre-made Mouse Igfbp2/IBP-2/Igfbp-2 siRNA oligo Duplex | 16008 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo696214 | Pre-made Cynomolgus/Rhesus macaque IGFBP2 siRNA oligo Duplex | 696214 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101088426 | Pre-made Cat/Feline IGFBP2/IGFBP-2 siRNA oligo Duplex | 101088426 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo488516 | Pre-made Dog/Canine IGFBP2 siRNA oligo Duplex | 488516 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo282260 | Pre-made Bovines/Cattle IGFBP2 siRNA oligo Duplex | 282260 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100034061 | Pre-made Equine/Horse IGFBP2 siRNA oligo Duplex | 100034061 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
IGFBP2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T64268-Ab | Human | Anti-Human IGFBP2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-rg-T64268-Ab | Rat | Anti-Rat IGFBP2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-mg-T64268-Ab | Mouse | Anti-Mouse IGFBP2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-T64268-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque IGFBP2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-felg-T64268-Ab | Cat/Feline | Anti-Cat/Feline IGFBP2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cang-T64268-Ab | Dog/Canine | Anti-Dog/Canine IGFBP2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-T64268-Ab | Bovines/Cattle | Anti-Bovines/Cattle IGFBP2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-equg-T64268-Ab | Equine/Horse | Anti-Equine/Horse IGFBP2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
IGFBP2 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T64268-Ag | Human | Human IGFBP2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T64268-Ag | Rat | Rat IGFBP2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T64268-Ag | Mouse | Mouse IGFBP2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T64268-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque IGFBP2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T64268-Ag | Cat/Feline | Cat/Feline IGFBP2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T64268-Ag | Dog/Canine | Dog/Canine IGFBP2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T64268-Ag | Bovines/Cattle | Bovines/Cattle IGFBP2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T64268-Ag | Equine/Horse | Equine/Horse IGFBP2 recombinant protein | Mammalian cell | Detail |