Recombinant multi-species IGFBP2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine IGFBP2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is one of six similar proteins that bind insulin-like growth factors I and II (IGF-I and IGF-II). The encoded protein can be secreted into the bloodstream, where it binds IGF-I and IGF-II with high affinity, or it can remain intracellular, interacting with many different ligands. High expression levels of this protein promote the growth of several types of tumors and may be predictive of the chances of recovery of the patient. Several transcript variants, one encoding a secreted isoform and the others encoding nonsecreted isoforms, have been found for this gene. [provided by RefSeq, Sep 2015]
The Alternative Names of target: BRL-BP,IBP-2,IBP2,IGF-BP53,IGF-binding protein 2,IGFBP-2,IGFBP2,ILGFBPA,Igfbp-2,Igfbp2,Insulin-like growth factor-binding protein 2,mIGFBP-2

Target products collectionGo to IGFBP2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T64268-Ag-1/ GM-Tg-hg-T64268-Ag-2 Human IGFBP2 protein Human
GM-Tg-rg-T64268-Ag-1/ GM-Tg-rg-T64268-Ag-2 Rat IGFBP2 protein Rat
GM-Tg-mg-T64268-Ag-1/ GM-Tg-mg-T64268-Ag-2 Mouse IGFBP2 protein Mouse
GM-Tg-cynog-T64268-Ag-1/ GM-Tg-cynog-T64268-Ag-2 Cynomolgus/Rhesus macaque IGFBP2 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T64268-Ag-1/ GM-Tg-felg-T64268-Ag-2 Feline IGFBP2 protein Feline
GM-Tg-cang-T64268-Ag-1/ GM-Tg-cang-T64268-Ag-2 Canine IGFBP2 protein Canine
GM-Tg-bovg-T64268-Ag-1/ GM-Tg-bovg-T64268-Ag-2 Bovine IGFBP2 protein Bovine
GM-Tg-equg-T64268-Ag-1/ GM-Tg-equg-T64268-Ag-2 Equine IGFBP2 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T64268-Ag-1/ GM-Tg-hg-T64268-Ag-2; GM-Tg-rg-T64268-Ag-1/ GM-Tg-rg-T64268-Ag-2;
GM-Tg-mg-T64268-Ag-1/ GM-Tg-mg-T64268-Ag-2; GM-Tg-cynog-T64268-Ag-1/ GM-Tg-cynog-T64268-Ag-2;
GM-Tg-felg-T64268-Ag-1/ GM-Tg-felg-T64268-Ag-2; GM-Tg-cang-T64268-Ag-1/ GM-Tg-cang-T64268-Ag-2;
GM-Tg-bovg-T64268-Ag-1/ GM-Tg-bovg-T64268-Ag-2; GM-Tg-equg-T64268-Ag-1/ GM-Tg-equg-T64268-Ag-2
Products Name IGFBP2 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name IGFBP2
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine IGFBP2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.