Explore HMGB1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene encodes a protein that belongs to the High Mobility Group-box superfamily. The encoded non-histone, nuclear DNA-binding protein regulates transcription, and is involved in organization of DNA. This protein plays a role in several cellular processes, including inflammation, cell differentiation and tumor cell migration. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Sep 2015]
| Target ID |
GM-T63595
|
| Target Name |
HMGB1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
3146
|
| Gene ID |
100033873 (Equus caballus), 101089823 (Felis catus), 15289 (Mus musculus), 25459 (Rattus norvegicus)
282691 (Bos taurus), 3146 (Homo sapiens), 403170 (Canis lupus familiaris), 712849 (Macaca mulatta)
|
| Target Alternative Names |
Ac2-008,HMG-1,HMG1,HMG3,HMGB1,High mobility group protein 1 (HMG-1),High mobility group protein B1,Hmg1,Hmgb1,SBP-1,p30
|
| Uniprot Accession |
Q08IE6,P63158,P63159,P10103,P09429,Q6YKA4
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer, Ovary Cancer
|
| Gene Ensembl |
ENSECAG00000008439, ENSMUSG00000066551, ENSBTAG00000018103, ENSG00000189403, ENSCAFG00845021967, ENSMMUG00000046615
|
Pre-made viral vector of HMGB1 cDNA Clones/ORF Plasmid
HMGB1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3146 | Pre-made Human HMGB1/HMG1/HMG3 siRNA oligo Duplex | 3146 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25459 | Pre-made Rat Hmgb1/Hmg1/Ac2-008 siRNA oligo Duplex | 25459 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo15289 | Pre-made Mouse Hmgb1/p30/Hmg1 siRNA oligo Duplex | 15289 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo712849 | Pre-made Cynomolgus/Rhesus macaque HMGB1 siRNA oligo Duplex | 712849 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101089823 | Pre-made Cat/Feline HMGB1 siRNA oligo Duplex | 101089823 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo403170 | Pre-made Dog/Canine HMGB1/HMG1 siRNA oligo Duplex | 403170 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo282691 | Pre-made Bovines/Cattle HMGB1 siRNA oligo Duplex | 282691 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100033873 | Pre-made Equine/Horse HMGB1/HMG-1 siRNA oligo Duplex | 100033873 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
HMGB1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T63595-Ab | Human | Anti-Human HMGB1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T63595-Ab | Rat | Anti-Rat HMGB1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T63595-Ab | Mouse | Anti-Mouse HMGB1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T63595-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque HMGB1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T63595-Ab | Cat/Feline | Anti-Cat/Feline HMGB1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T63595-Ab | Dog/Canine | Anti-Dog/Canine HMGB1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T63595-Ab | Bovines/Cattle | Anti-Bovines/Cattle HMGB1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T63595-Ab | Equine/Horse | Anti-Equine/Horse HMGB1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
HMGB1 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T63595-Ag | Human | Human HMGB1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T63595-Ag | Rat | Rat HMGB1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T63595-Ag | Mouse | Mouse HMGB1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T63595-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque HMGB1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T63595-Ag | Cat/Feline | Cat/Feline HMGB1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T63595-Ag | Dog/Canine | Dog/Canine HMGB1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T63595-Ag | Bovines/Cattle | Bovines/Cattle HMGB1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T63595-Ag | Equine/Horse | Equine/Horse HMGB1 VLP (virus-like particle) | HEK293 | Products Developing |
