Explore SORD/Sorbitol dehydrogenase gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Introcelluar Protein.
Sorbitol dehydrogenase (SORD; EC 1.1.1.14) catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase (ALDR1; MIM 103880), makes up the sorbitol pathway that is believed to play an important role in the development of diabetic complications (summarized by Carr and Markham, 1995 [PubMed 8535074]). The first reaction of the pathway (also called the polyol pathway) is the reduction of glucose to sorbitol by ALDR1 with NADPH as the cofactor. SORD then oxidizes the sorbitol to fructose using NAD(+) cofactor.[supplied by OMIM, Jul 2010]
| Target ID |
GM-T59445
|
| Target Name |
SORD/Sorbitol dehydrogenase
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
6652
|
| Gene ID |
100070575 (Equus caballus), 101088085 (Felis catus), 20322 (Mus musculus), 24788 (Rattus norvegicus)
487535 (Canis lupus familiaris), 508954 (Bos taurus), 6652 (Homo sapiens), 712784 (Macaca mulatta)
|
| Target Alternative Names |
SORD,Sord,SDH,XDH,Sdh1,Sdh-1,Sodh-1,RDH,HMNR8,SORD1,SORDD,HEL-S-95n
|
| Uniprot Accession |
Q64442,P27867,Q58D31,Q00796
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
|
| Disease from KEGG |
Metabolic pathways, Pentose and glucuronate interconversions
|
| Gene Ensembl |
ENSECAG00000005266, ENSMUSG00000027227, ENSCAFG00845028851, ENSBTAG00000025496, ENSG00000140263, ENSMMUG00000015971
|
| Target Classification |
|
Pre-made viral vector of SORD/Sorbitol dehydrogenase cDNA Clones/ORF Plasmid
SORD/Sorbitol dehydrogenase siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo6652 | Pre-made Human SORD/RDH/SDH siRNA oligo Duplex | 6652 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo24788 | Pre-made Rat Sord/SDH/XDH siRNA oligo Duplex | 24788 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo20322 | Pre-made Mouse Sord/SDH/XDH siRNA oligo Duplex | 20322 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo712784 | Pre-made Cynomolgus/Rhesus macaque SORD siRNA oligo Duplex | 712784 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101088085 | Pre-made Cat/Feline SORD siRNA oligo Duplex | 101088085 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo487535 | Pre-made Dog/Canine SORD siRNA oligo Duplex | 487535 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo508954 | Pre-made Bovines/Cattle SORD/SDH/XDH siRNA oligo Duplex | 508954 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100070575 | Pre-made Equine/Horse SORD siRNA oligo Duplex | 100070575 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
SORD/Sorbitol dehydrogenase antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T59445-Ab | Human | Anti-Human SORD/Sorbitol dehydrogenase monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T59445-Ab | Rat | Anti-Rat SORD/Sorbitol dehydrogenase monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T59445-Ab | Mouse | Anti-Mouse SORD/Sorbitol dehydrogenase monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T59445-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque SORD/Sorbitol dehydrogenase monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T59445-Ab | Cat/Feline | Anti-Cat/Feline SORD/Sorbitol dehydrogenase monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T59445-Ab | Dog/Canine | Anti-Dog/Canine SORD/Sorbitol dehydrogenase monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T59445-Ab | Bovines/Cattle | Anti-Bovines/Cattle SORD/Sorbitol dehydrogenase monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T59445-Ab | Equine/Horse | Anti-Equine/Horse SORD/Sorbitol dehydrogenase monoclonal antibody | mab | Therapeutics Target antibody | Detail |
SORD/Sorbitol dehydrogenase recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T59445-Ag | Human | Human SORD/Sorbitol dehydrogenase recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T59445-Ag | Rat | Rat SORD/Sorbitol dehydrogenase recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T59445-Ag | Mouse | Mouse SORD/Sorbitol dehydrogenase recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T59445-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque SORD/Sorbitol dehydrogenase recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T59445-Ag | Cat/Feline | Cat/Feline SORD/Sorbitol dehydrogenase recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T59445-Ag | Dog/Canine | Dog/Canine SORD/Sorbitol dehydrogenase recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T59445-Ag | Bovines/Cattle | Bovines/Cattle SORD/Sorbitol dehydrogenase recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T59445-Ag | Equine/Horse | Equine/Horse SORD/Sorbitol dehydrogenase recombinant protein | Mammalian cell | Detail |
