Explore IL-11/IL11 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Secreted Protein/Potential Cytokines.
The protein encoded by this gene is a member of the gp130 family of cytokines. These cytokines drive the assembly of multisubunit receptor complexes, all of which contain at least one molecule of the transmembrane signaling receptor IL6ST (gp130). This cytokine is shown to stimulate the T-cell-dependent development of immunoglobulin-producing B cells. It is also found to support the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jun 2012]
| Target ID |
GM-T56308
|
| Target Name |
IL-11/IL11
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
3589
|
| Gene ID |
100056037 (Equus caballus), 100337295 (Bos taurus), 101085086 (Felis catus), 16156 (Mus musculus)
171040 (Rattus norvegicus), 3589 (Homo sapiens), 611309 (Canis lupus familiaris), 722817 (Macaca mulatta)
|
| Target Alternative Names |
AGIF,Adipogenesis inhibitory factor (AGIF),IL-11,IL11,Il-11,Il11,Interleukin-11
|
| Uniprot Accession |
P47873,Q99MF5,P20809
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Therapeutics Target, Cytokine Target
|
| Disease |
cancer
|
| Disease from KEGG |
Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway, Hematopoietic cell lineage, Rheumatoid arthritis
|
| Gene Ensembl |
ENSECAG00000014511, ENSBTAG00000057283, ENSMUSG00000004371, ENSG00000095752, ENSCAFG00845000969
|
| Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of IL-11/IL11 cDNA Clones/ORF Plasmid
IL-11/IL11 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3589 | Pre-made Human IL11/AGIF/IL-11 siRNA oligo Duplex | 3589 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo171040 | Pre-made Rat Il11/Il-11 siRNA oligo Duplex | 171040 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo16156 | Pre-made Mouse Il11/IL-11 siRNA oligo Duplex | 16156 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo722817 | Pre-made Cynomolgus/Rhesus macaque IL11 siRNA oligo Duplex | 722817 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101085086 | Pre-made Cat/Feline IL11 siRNA oligo Duplex | 101085086 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo611309 | Pre-made Dog/Canine IL11 siRNA oligo Duplex | 611309 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100337295 | Pre-made Bovines/Cattle IL11 siRNA oligo Duplex | 100337295 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100056037 | Pre-made Equine/Horse IL11 siRNA oligo Duplex | 100056037 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
IL-11/IL11 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T56308-Ab | Human | Anti-Human IL-11/IL11 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-rg-T56308-Ab | Rat | Anti-Rat IL-11/IL11 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-mg-T56308-Ab | Mouse | Anti-Mouse IL-11/IL11 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-T56308-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque IL-11/IL11 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-felg-T56308-Ab | Cat/Feline | Anti-Cat/Feline IL-11/IL11 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cang-T56308-Ab | Dog/Canine | Anti-Dog/Canine IL-11/IL11 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-T56308-Ab | Bovines/Cattle | Anti-Bovines/Cattle IL-11/IL11 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-equg-T56308-Ab | Equine/Horse | Anti-Equine/Horse IL-11/IL11 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
IL-11/IL11 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T56308-Ag | Human | Human IL-11/IL11 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T56308-Ag | Rat | Rat IL-11/IL11 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T56308-Ag | Mouse | Mouse IL-11/IL11 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T56308-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque IL-11/IL11 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T56308-Ag | Cat/Feline | Cat/Feline IL-11/IL11 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T56308-Ag | Dog/Canine | Dog/Canine IL-11/IL11 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T56308-Ag | Bovines/Cattle | Bovines/Cattle IL-11/IL11 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T56308-Ag | Equine/Horse | Equine/Horse IL-11/IL11 recombinant protein | Mammalian cell | Detail |
