Recombinant multi-species IL-11/IL11 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine IL-11/IL11 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a member of the gp130 family of cytokines. These cytokines drive the assembly of multisubunit receptor complexes, all of which contain at least one molecule of the transmembrane signaling receptor IL6ST (gp130). This cytokine is shown to stimulate the T-cell-dependent development of immunoglobulin-producing B cells. It is also found to support the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jun 2012]
The Alternative Names of target: AGIF,Adipogenesis inhibitory factor (AGIF),IL-11,IL11,Il-11,Il11,Interleukin-11

Target products collectionGo to IL-11/IL11 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T56308-Ag-1/ GM-Tg-hg-T56308-Ag-2 Human IL-11/IL11 protein Human
GM-Tg-rg-T56308-Ag-1/ GM-Tg-rg-T56308-Ag-2 Rat IL-11/IL11 protein Rat
GM-Tg-mg-T56308-Ag-1/ GM-Tg-mg-T56308-Ag-2 Mouse IL-11/IL11 protein Mouse
GM-Tg-cynog-T56308-Ag-1/ GM-Tg-cynog-T56308-Ag-2 Cynomolgus/Rhesus macaque IL-11/IL11 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T56308-Ag-1/ GM-Tg-felg-T56308-Ag-2 Feline IL-11/IL11 protein Feline
GM-Tg-cang-T56308-Ag-1/ GM-Tg-cang-T56308-Ag-2 Canine IL-11/IL11 protein Canine
GM-Tg-bovg-T56308-Ag-1/ GM-Tg-bovg-T56308-Ag-2 Bovine IL-11/IL11 protein Bovine
GM-Tg-equg-T56308-Ag-1/ GM-Tg-equg-T56308-Ag-2 Equine IL-11/IL11 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T56308-Ag-1/ GM-Tg-hg-T56308-Ag-2; GM-Tg-rg-T56308-Ag-1/ GM-Tg-rg-T56308-Ag-2;
GM-Tg-mg-T56308-Ag-1/ GM-Tg-mg-T56308-Ag-2; GM-Tg-cynog-T56308-Ag-1/ GM-Tg-cynog-T56308-Ag-2;
GM-Tg-felg-T56308-Ag-1/ GM-Tg-felg-T56308-Ag-2; GM-Tg-cang-T56308-Ag-1/ GM-Tg-cang-T56308-Ag-2;
GM-Tg-bovg-T56308-Ag-1/ GM-Tg-bovg-T56308-Ag-2; GM-Tg-equg-T56308-Ag-1/ GM-Tg-equg-T56308-Ag-2
Products Name IL-11/IL11 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name IL-11/IL11
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine IL-11/IL11 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.