Explore SAA1 gene products and cross-species
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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a member of the serum amyloid A family of apolipoproteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a major acute phase protein that is highly expressed in response to inflammation and tissue injury. This protein also plays an important role in HDL metabolism and cholesterol homeostasis. High levels of this protein are associated with chronic inflammatory diseases including atherosclerosis, rheumatoid arthritis, Alzheimer's disease and Crohn's disease. This protein may also be a potential biomarker for certain tumors. Finally, antimicrobial activity against S. aureus and E. coli resides in the N-terminal portion of the mature protein. Alternate splicing results in multiple transcript variants that encode the same protein. A pseudogene of this gene is found on chromosome 11. [provided by RefSeq, Jul 2020]
| Target ID |
GM-T55447
|
| Target Name |
SAA1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
6288
|
| Gene ID |
119865027 (Canis lupus familiaris), 6288 (Homo sapiens), 694944 (Macaca mulatta)
|
| Target Alternative Names |
PIG4,SAA,SAA1,SAA2,Serum amyloid A-1 protein,TP53I4
|
| Uniprot Accession |
P0DJI8,P02738
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Therapeutics Target, Diagnostics Biomarker, INN Index
|
| Gene Ensembl |
ENSCAFG00845015612, ENSG00000173432, ENSMMUG00000060306
|
Pre-made viral vector of SAA1 cDNA Clones/ORF Plasmid
SAA1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo6288 | Pre-made Human SAA1/SAA/PIG4 siRNA oligo Duplex | 6288 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo694944 | Pre-made Cynomolgus/Rhesus macaque SAA1 siRNA oligo Duplex | 694944 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo119865027 | Pre-made Dog/Canine SAA1 siRNA oligo Duplex | 119865027 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
SAA1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T55447-Ab | Human | Anti-Human SAA1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Diagnostic target antibody | Detail |
| GM-Tg-cynog-T55447-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque SAA1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Diagnostic target antibody | Detail |
| GM-Tg-cang-T55447-Ab | Dog/Canine | Anti-Dog/Canine SAA1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Diagnostic target antibody | Detail |
SAA1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T55447-Ag | Human | Human SAA1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T55447-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque SAA1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T55447-Ag | Dog/Canine | Dog/Canine SAA1 recombinant protein | Mammalian cell | Detail |
