Recombinant multi-species SAA1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SAA1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the serum amyloid A family of apolipoproteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a major acute phase protein that is highly expressed in response to inflammation and tissue injury. This protein also plays an important role in HDL metabolism and cholesterol homeostasis. High levels of this protein are associated with chronic inflammatory diseases including atherosclerosis, rheumatoid arthritis, Alzheimer's disease and Crohn's disease. This protein may also be a potential biomarker for certain tumors. Finally, antimicrobial activity against S. aureus and E. coli resides in the N-terminal portion of the mature protein. Alternate splicing results in multiple transcript variants that encode the same protein. A pseudogene of this gene is found on chromosome 11. [provided by RefSeq, Jul 2020]
The Alternative Names of target: PIG4,SAA,SAA1,SAA2,Serum amyloid A-1 protein,TP53I4

Target products collectionGo to SAA1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T55447-Ag-1/ GM-Tg-hg-T55447-Ag-2 Human SAA1 protein Human
GM-Tg-rg-T55447-Ag-1/ GM-Tg-rg-T55447-Ag-2 Rat SAA1 protein Rat
GM-Tg-mg-T55447-Ag-1/ GM-Tg-mg-T55447-Ag-2 Mouse SAA1 protein Mouse
GM-Tg-cynog-T55447-Ag-1/ GM-Tg-cynog-T55447-Ag-2 Cynomolgus/Rhesus macaque SAA1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T55447-Ag-1/ GM-Tg-felg-T55447-Ag-2 Feline SAA1 protein Feline
GM-Tg-cang-T55447-Ag-1/ GM-Tg-cang-T55447-Ag-2 Canine SAA1 protein Canine
GM-Tg-bovg-T55447-Ag-1/ GM-Tg-bovg-T55447-Ag-2 Bovine SAA1 protein Bovine
GM-Tg-equg-T55447-Ag-1/ GM-Tg-equg-T55447-Ag-2 Equine SAA1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T55447-Ag-1/ GM-Tg-hg-T55447-Ag-2; GM-Tg-rg-T55447-Ag-1/ GM-Tg-rg-T55447-Ag-2;
GM-Tg-mg-T55447-Ag-1/ GM-Tg-mg-T55447-Ag-2; GM-Tg-cynog-T55447-Ag-1/ GM-Tg-cynog-T55447-Ag-2;
GM-Tg-felg-T55447-Ag-1/ GM-Tg-felg-T55447-Ag-2; GM-Tg-cang-T55447-Ag-1/ GM-Tg-cang-T55447-Ag-2;
GM-Tg-bovg-T55447-Ag-1/ GM-Tg-bovg-T55447-Ag-2; GM-Tg-equg-T55447-Ag-1/ GM-Tg-equg-T55447-Ag-2
Products Name SAA1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name SAA1
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SAA1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.