Explore Serpin F1/PEDF/SERPINF1 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a member of the serpin family that does not display the serine protease inhibitory activity shown by many of the other serpin proteins. The encoded protein is secreted and strongly inhibits angiogenesis. In addition, this protein is a neurotrophic factor involved in neuronal differentiation in retinoblastoma cells. Mutations in this gene were found in individuals with osteogenesis imperfecta, type VI. [provided by RefSeq, Aug 2016]
| Target ID |
GM-T54447
|
| Target Name |
Serpin F1/PEDF/SERPINF1
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
5176
|
| Gene ID |
100072415 (Equus caballus), 101099915 (Felis catus), 20317 (Mus musculus), 281386 (Bos taurus) 287526 (Rattus norvegicus), 5176 (Homo sapiens), 611276 (Canis lupus familiaris), 721262 (Macaca mulatta)
|
| Target Alternative Names |
Cell proliferation-inducing gene 35 protein,Dmrs91,EPC-1,OI12,OI6,PEDF,PIG35,Pedf,Pedfl,Pigment epithelium-derived factor,SERPINF1,Sdf3,Serpin F1,Serpinf1
|
| Uniprot Accession |
P97298,Q95121,P36955
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Therapeutics Target
|
| Disease |
Complications of kidney transplant, Dent disease, Diabetic Nephropathy, Perinatal necrotizing enterocolitis
|
| Disease from KEGG |
Wnt signaling pathway
|
| Gene Ensembl |
ENSECAG00000022279, ENSMUSG00000000753, ENSBTAG00000009705, ENSG00000132386, ENSCAFG00845013723, ENSMMUG00000022194
|
Pre-made viral vector of Serpin F1/PEDF/SERPINF1 cDNA Clones/ORF Plasmid
Serpin F1/PEDF/SERPINF1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo5176 | Pre-made Human SERPINF1/OI6/OI12 siRNA oligo Duplex | 5176 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo287526 | Pre-made Rat Serpinf1/Pedf/Dmrs91 siRNA oligo Duplex | 287526 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo20317 | Pre-made Mouse Serpinf1/Pedf/Sdf3 siRNA oligo Duplex | 20317 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo721262 | Pre-made Cynomolgus/Rhesus macaque SERPINF1 siRNA oligo Duplex | 721262 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101099915 | Pre-made Cat/Feline SERPINF1 siRNA oligo Duplex | 101099915 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo611276 | Pre-made Dog/Canine SERPINF1/PEDF siRNA oligo Duplex | 611276 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281386 | Pre-made Bovines/Cattle SERPINF1/PEDF siRNA oligo Duplex | 281386 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100072415 | Pre-made Equine/Horse SERPINF1/PEDF siRNA oligo Duplex | 100072415 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
Serpin F1/PEDF/SERPINF1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T54447-Ab | Human | Anti-Human Serpin F1/PEDF/SERPINF1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T54447-Ab | Rat | Anti-Rat Serpin F1/PEDF/SERPINF1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T54447-Ab | Mouse | Anti-Mouse Serpin F1/PEDF/SERPINF1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T54447-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque Serpin F1/PEDF/SERPINF1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T54447-Ab | Cat/Feline | Anti-Cat/Feline Serpin F1/PEDF/SERPINF1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T54447-Ab | Dog/Canine | Anti-Dog/Canine Serpin F1/PEDF/SERPINF1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T54447-Ab | Bovines/Cattle | Anti-Bovines/Cattle Serpin F1/PEDF/SERPINF1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T54447-Ab | Equine/Horse | Anti-Equine/Horse Serpin F1/PEDF/SERPINF1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
Serpin F1/PEDF/SERPINF1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T54447-Ag | Human | Human Serpin F1/PEDF/SERPINF1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T54447-Ag | Rat | Rat Serpin F1/PEDF/SERPINF1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T54447-Ag | Mouse | Mouse Serpin F1/PEDF/SERPINF1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T54447-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque Serpin F1/PEDF/SERPINF1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T54447-Ag | Cat/Feline | Cat/Feline Serpin F1/PEDF/SERPINF1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T54447-Ag | Dog/Canine | Dog/Canine Serpin F1/PEDF/SERPINF1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T54447-Ag | Bovines/Cattle | Bovines/Cattle Serpin F1/PEDF/SERPINF1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T54447-Ag | Equine/Horse | Equine/Horse Serpin F1/PEDF/SERPINF1 recombinant protein | Mammalian cell | Detail |