Recombinant multi-species Serpin F1/PEDF/SERPINF1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine Serpin F1/PEDF/SERPINF1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the serpin family that does not display the serine protease inhibitory activity shown by many of the other serpin proteins. The encoded protein is secreted and strongly inhibits angiogenesis. In addition, this protein is a neurotrophic factor involved in neuronal differentiation in retinoblastoma cells. Mutations in this gene were found in individuals with osteogenesis imperfecta, type VI. [provided by RefSeq, Aug 2016]
The Alternative Names of target: Cell proliferation-inducing gene 35 protein,Dmrs91,EPC-1,OI12,OI6,PEDF,PIG35,Pedf,Pedfl,Pigment epithelium-derived factor,SERPINF1,Sdf3,Serpin F1,Serpinf1
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T54447-Ag-1/ GM-Tg-hg-T54447-Ag-2 | Human Serpin F1/PEDF/SERPINF1 protein | Human |
| GM-Tg-rg-T54447-Ag-1/ GM-Tg-rg-T54447-Ag-2 | Rat Serpin F1/PEDF/SERPINF1 protein | Rat |
| GM-Tg-mg-T54447-Ag-1/ GM-Tg-mg-T54447-Ag-2 | Mouse Serpin F1/PEDF/SERPINF1 protein | Mouse |
| GM-Tg-cynog-T54447-Ag-1/ GM-Tg-cynog-T54447-Ag-2 | Cynomolgus/Rhesus macaque Serpin F1/PEDF/SERPINF1 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T54447-Ag-1/ GM-Tg-felg-T54447-Ag-2 | Feline Serpin F1/PEDF/SERPINF1 protein | Feline |
| GM-Tg-cang-T54447-Ag-1/ GM-Tg-cang-T54447-Ag-2 | Canine Serpin F1/PEDF/SERPINF1 protein | Canine |
| GM-Tg-bovg-T54447-Ag-1/ GM-Tg-bovg-T54447-Ag-2 | Bovine Serpin F1/PEDF/SERPINF1 protein | Bovine |
| GM-Tg-equg-T54447-Ag-1/ GM-Tg-equg-T54447-Ag-2 | Equine Serpin F1/PEDF/SERPINF1 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-T54447-Ag-1/ GM-Tg-hg-T54447-Ag-2;
GM-Tg-rg-T54447-Ag-1/ GM-Tg-rg-T54447-Ag-2;
GM-Tg-mg-T54447-Ag-1/ GM-Tg-mg-T54447-Ag-2; GM-Tg-cynog-T54447-Ag-1/ GM-Tg-cynog-T54447-Ag-2; GM-Tg-felg-T54447-Ag-1/ GM-Tg-felg-T54447-Ag-2; GM-Tg-cang-T54447-Ag-1/ GM-Tg-cang-T54447-Ag-2; GM-Tg-bovg-T54447-Ag-1/ GM-Tg-bovg-T54447-Ag-2; GM-Tg-equg-T54447-Ag-1/ GM-Tg-equg-T54447-Ag-2 |
| Products Name | Serpin F1/PEDF/SERPINF1 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | Serpin F1/PEDF/SERPINF1 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine Serpin F1/PEDF/SERPINF1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.