Explore Neuropeptide Y/NPY gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a neuropeptide that is widely expressed in the central nervous system and influences many physiological processes, including cortical excitability, stress response, food intake, circadian rhythms, and cardiovascular function. The neuropeptide functions through G protein-coupled receptors to inhibit adenylyl cyclase, activate mitogen-activated protein kinase (MAPK), regulate intracellular calcium levels, and activate potassium channels. A polymorphism in this gene resulting in a change of leucine 7 to proline in the signal peptide is associated with elevated cholesterol levels, higher alcohol consumption, and may be a risk factor for various metabolic and cardiovascular diseases. The protein also exhibits antimicrobial activity against bacteria and fungi. [provided by RefSeq, Oct 2014]
| Target ID |
GM-T51671
|
| Target Name |
Neuropeptide Y/NPY
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
4852
|
| Gene ID |
100053806 (Equus caballus), 101096968 (Felis catus), 109648 (Mus musculus), 24604 (Rattus norvegicus) 475257 (Canis lupus familiaris), 4852 (Homo sapiens), 504216 (Bos taurus), 574114 (Macaca mulatta)
|
| Target Alternative Names |
0710005A05Rik,NPY,NPY02,Neuropeptide Y,Npy,PYY4,Pro-neuropeptide Y,RATNPY,RATNPY02
|
| Uniprot Accession |
P57774,P07808,P01303,Q6RUW3,Q9XSW6
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
cAMP signaling pathway, Neuroactive ligand-receptor interaction, Adipocytokine signaling pathway, Regulation of lipolysis in adipocytes
|
| Gene Ensembl |
ENSMUSG00000029819, ENSCAFG00845010065, ENSG00000122585, ENSBTAG00000004503, ENSMMUG00000009818
|
Pre-made viral vector of Neuropeptide Y/NPY cDNA Clones/ORF Plasmid
Neuropeptide Y/NPY siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo4852 | Pre-made Human NPY/PYY4 siRNA oligo Duplex | 4852 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo24604 | Pre-made Rat Npy/NPY02/RATNPY siRNA oligo Duplex | 24604 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo109648 | Pre-made Mouse Npy/0710005A05Rik siRNA oligo Duplex | 109648 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo574114 | Pre-made Cynomolgus/Rhesus macaque NPY siRNA oligo Duplex | 574114 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101096968 | Pre-made Cat/Feline NPY siRNA oligo Duplex | 101096968 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo475257 | Pre-made Dog/Canine NPY siRNA oligo Duplex | 475257 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo504216 | Pre-made Bovines/Cattle NPY siRNA oligo Duplex | 504216 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100053806 | Pre-made Equine/Horse NPY siRNA oligo Duplex | 100053806 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
Neuropeptide Y/NPY antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T51671-Ab | Human | Anti-Human Neuropeptide Y/NPY monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T51671-Ab | Rat | Anti-Rat Neuropeptide Y/NPY monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T51671-Ab | Mouse | Anti-Mouse Neuropeptide Y/NPY monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T51671-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque Neuropeptide Y/NPY monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T51671-Ab | Cat/Feline | Anti-Cat/Feline Neuropeptide Y/NPY monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T51671-Ab | Dog/Canine | Anti-Dog/Canine Neuropeptide Y/NPY monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T51671-Ab | Bovines/Cattle | Anti-Bovines/Cattle Neuropeptide Y/NPY monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T51671-Ab | Equine/Horse | Anti-Equine/Horse Neuropeptide Y/NPY monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
Neuropeptide Y/NPY recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T51671-Ag | Human | Human Neuropeptide Y/NPY recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T51671-Ag | Rat | Rat Neuropeptide Y/NPY recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T51671-Ag | Mouse | Mouse Neuropeptide Y/NPY recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T51671-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque Neuropeptide Y/NPY recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T51671-Ag | Cat/Feline | Cat/Feline Neuropeptide Y/NPY recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T51671-Ag | Dog/Canine | Dog/Canine Neuropeptide Y/NPY recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T51671-Ag | Bovines/Cattle | Bovines/Cattle Neuropeptide Y/NPY recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T51671-Ag | Equine/Horse | Equine/Horse Neuropeptide Y/NPY recombinant protein | Mammalian cell | Detail |