Recombinant multi-species Neuropeptide Y/NPY protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine Neuropeptide Y/NPY protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a neuropeptide that is widely expressed in the central nervous system and influences many physiological processes, including cortical excitability, stress response, food intake, circadian rhythms, and cardiovascular function. The neuropeptide functions through G protein-coupled receptors to inhibit adenylyl cyclase, activate mitogen-activated protein kinase (MAPK), regulate intracellular calcium levels, and activate potassium channels. A polymorphism in this gene resulting in a change of leucine 7 to proline in the signal peptide is associated with elevated cholesterol levels, higher alcohol consumption, and may be a risk factor for various metabolic and cardiovascular diseases. The protein also exhibits antimicrobial activity against bacteria and fungi. [provided by RefSeq, Oct 2014]
The Alternative Names of target: 0710005A05Rik,NPY,NPY02,Neuropeptide Y,Npy,PYY4,Pro-neuropeptide Y,RATNPY,RATNPY02
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T51671-Ag-1/ GM-Tg-hg-T51671-Ag-2 | Human Neuropeptide Y/NPY protein | Human |
| GM-Tg-rg-T51671-Ag-1/ GM-Tg-rg-T51671-Ag-2 | Rat Neuropeptide Y/NPY protein | Rat |
| GM-Tg-mg-T51671-Ag-1/ GM-Tg-mg-T51671-Ag-2 | Mouse Neuropeptide Y/NPY protein | Mouse |
| GM-Tg-cynog-T51671-Ag-1/ GM-Tg-cynog-T51671-Ag-2 | Cynomolgus/Rhesus macaque Neuropeptide Y/NPY protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T51671-Ag-1/ GM-Tg-felg-T51671-Ag-2 | Feline Neuropeptide Y/NPY protein | Feline |
| GM-Tg-cang-T51671-Ag-1/ GM-Tg-cang-T51671-Ag-2 | Canine Neuropeptide Y/NPY protein | Canine |
| GM-Tg-bovg-T51671-Ag-1/ GM-Tg-bovg-T51671-Ag-2 | Bovine Neuropeptide Y/NPY protein | Bovine |
| GM-Tg-equg-T51671-Ag-1/ GM-Tg-equg-T51671-Ag-2 | Equine Neuropeptide Y/NPY protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-T51671-Ag-1/ GM-Tg-hg-T51671-Ag-2;
GM-Tg-rg-T51671-Ag-1/ GM-Tg-rg-T51671-Ag-2;
GM-Tg-mg-T51671-Ag-1/ GM-Tg-mg-T51671-Ag-2; GM-Tg-cynog-T51671-Ag-1/ GM-Tg-cynog-T51671-Ag-2; GM-Tg-felg-T51671-Ag-1/ GM-Tg-felg-T51671-Ag-2; GM-Tg-cang-T51671-Ag-1/ GM-Tg-cang-T51671-Ag-2; GM-Tg-bovg-T51671-Ag-1/ GM-Tg-bovg-T51671-Ag-2; GM-Tg-equg-T51671-Ag-1/ GM-Tg-equg-T51671-Ag-2 |
| Products Name | Neuropeptide Y/NPY protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | Neuropeptide Y/NPY |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine Neuropeptide Y/NPY protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
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Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
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innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.