Explore IL-21/IL21 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a member of the common-gamma chain family of cytokines with immunoregulatory activity. The encoded protein plays a role in both the innate and adaptive immune responses by inducing the differentiation, proliferation and activity of multiple target cells including macrophages, natural killer cells, B cells and cytotoxic T cells. Dysregulation of this gene plays a role in multiple immune-mediated diseases including lupus, psoriasis and chronic inflammatory diseases. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
| Target ID |
GM-T51223
|
| Target Name |
IL-21/IL21
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
59067
|
| Gene ID |
100063803 (Equus caballus), 101087399 (Felis catus), 365769 (Rattus norvegicus), 378475 (Bos taurus)
442935 (Canis lupus familiaris), 59067 (Homo sapiens), 60505 (Mus musculus), 708125 (Macaca mulatta)
|
| Target Alternative Names |
CVID11,IL-21,IL21,Il21,Interleukin-21,Za11
|
| Uniprot Accession |
A3QPB9,Q76LU5,Q6L7I9,Q9HBE4,Q9ES17
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Therapeutics Target, INN Index
|
| Disease |
cancer
|
| Disease from KEGG |
Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway, Th17 cell differentiation, Inflammatory bowel disease
|
| Gene Ensembl |
ENSECAG00000037491, ENSBTAG00000012368, ENSCAFG00845020106, ENSG00000138684, ENSMUSG00000027718, ENSMMUG00000049383
|
| Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of IL-21/IL21 cDNA Clones/ORF Plasmid
IL-21/IL21 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo59067 | Pre-made Human IL21/Za11/IL-21 siRNA oligo Duplex | 59067 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo365769 | Pre-made Rat Il21/IL-21 siRNA oligo Duplex | 365769 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo60505 | Pre-made Mouse Il21/IL-21 siRNA oligo Duplex | 60505 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo708125 | Pre-made Cynomolgus/Rhesus macaque IL21 siRNA oligo Duplex | 708125 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101087399 | Pre-made Cat/Feline IL21 siRNA oligo Duplex | 101087399 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo442935 | Pre-made Dog/Canine IL21/IL-21 siRNA oligo Duplex | 442935 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo378475 | Pre-made Bovines/Cattle IL21 siRNA oligo Duplex | 378475 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100063803 | Pre-made Equine/Horse IL21 siRNA oligo Duplex | 100063803 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
IL-21/IL21 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T51223-Ab | Human | Anti-Human IL-21/IL21 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T51223-Ab | Rat | Anti-Rat IL-21/IL21 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T51223-Ab | Mouse | Anti-Mouse IL-21/IL21 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T51223-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque IL-21/IL21 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T51223-Ab | Cat/Feline | Anti-Cat/Feline IL-21/IL21 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T51223-Ab | Dog/Canine | Anti-Dog/Canine IL-21/IL21 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T51223-Ab | Bovines/Cattle | Anti-Bovines/Cattle IL-21/IL21 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T51223-Ab | Equine/Horse | Anti-Equine/Horse IL-21/IL21 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
IL-21/IL21 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T51223-Ag | Human | Human IL-21/IL21 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T51223-Ag | Rat | Rat IL-21/IL21 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T51223-Ag | Mouse | Mouse IL-21/IL21 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T51223-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque IL-21/IL21 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T51223-Ag | Cat/Feline | Cat/Feline IL-21/IL21 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T51223-Ag | Dog/Canine | Dog/Canine IL-21/IL21 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T51223-Ag | Bovines/Cattle | Bovines/Cattle IL-21/IL21 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T51223-Ag | Equine/Horse | Equine/Horse IL-21/IL21 recombinant protein | Mammalian cell | Detail |
