Explore BMP-7/BMP7 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone, kidney and brown adipose tissue development. Additionally, this protein induces ectopic bone formation and may promote fracture healing in human patients. [provided by RefSeq, Jul 2016]
| Target ID |
GM-T50289
|
| Target Name |
BMP-7/BMP7
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
655
|
| Gene ID |
100050299 (Equus caballus), 101094168 (Felis catus), 12162 (Mus musculus), 477270 (Canis lupus familiaris)
540595 (Bos taurus), 655 (Homo sapiens), 696948 (Macaca mulatta), 85272 (Rattus norvegicus)
|
| Target Alternative Names |
BMP-7,BMP7,Bmp7,Bone morphogenetic protein 7,OP-1,OP1,Osteogenic protein 1 (OP-1)
|
| Uniprot Accession |
P23359,P34819,P18075
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Therapeutics Target, Cytokine Target
|
| Disease |
cancer
|
| Disease from KEGG |
Cytokine-cytokine receptor interaction, TGF-beta signaling pathway, Axon guidance, Hippo signaling pathway
|
| Gene Ensembl |
ENSECAG00000002918, ENSMUSG00000008999, ENSCAFG00845029691, ENSBTAG00000015362, ENSG00000101144, ENSMMUG00000004074
|
| Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of BMP-7/BMP7 cDNA Clones/ORF Plasmid
BMP-7/BMP7 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo655 | Pre-made Human BMP7/OP-1 siRNA oligo Duplex | 655 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo85272 | Pre-made Rat Bmp7/BMP-7 siRNA oligo Duplex | 85272 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo12162 | Pre-made Mouse Bmp7/OP1 siRNA oligo Duplex | 12162 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo696948 | Pre-made Cynomolgus/Rhesus macaque BMP7 siRNA oligo Duplex | 696948 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101094168 | Pre-made Cat/Feline BMP7 siRNA oligo Duplex | 101094168 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo477270 | Pre-made Dog/Canine BMP7/OP-1/BMP-7 siRNA oligo Duplex | 477270 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo540595 | Pre-made Bovines/Cattle BMP7 siRNA oligo Duplex | 540595 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100050299 | Pre-made Equine/Horse BMP7 siRNA oligo Duplex | 100050299 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
BMP-7/BMP7 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T50289-Ab | Human | Anti-Human BMP-7/BMP7 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-rg-T50289-Ab | Rat | Anti-Rat BMP-7/BMP7 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-mg-T50289-Ab | Mouse | Anti-Mouse BMP-7/BMP7 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-T50289-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque BMP-7/BMP7 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-felg-T50289-Ab | Cat/Feline | Anti-Cat/Feline BMP-7/BMP7 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cang-T50289-Ab | Dog/Canine | Anti-Dog/Canine BMP-7/BMP7 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-T50289-Ab | Bovines/Cattle | Anti-Bovines/Cattle BMP-7/BMP7 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-equg-T50289-Ab | Equine/Horse | Anti-Equine/Horse BMP-7/BMP7 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
BMP-7/BMP7 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T50289-Ag | Human | Human BMP-7/BMP7 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T50289-Ag | Rat | Rat BMP-7/BMP7 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T50289-Ag | Mouse | Mouse BMP-7/BMP7 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T50289-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque BMP-7/BMP7 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T50289-Ag | Cat/Feline | Cat/Feline BMP-7/BMP7 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T50289-Ag | Dog/Canine | Dog/Canine BMP-7/BMP7 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T50289-Ag | Bovines/Cattle | Bovines/Cattle BMP-7/BMP7 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T50289-Ag | Equine/Horse | Equine/Horse BMP-7/BMP7 recombinant protein | Mammalian cell | Detail |
