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Target
sublocation: Introcelluar Protein.
This gene encodes a protein that belongs to the non-histone chromosomal high mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential components of the enhancesome. This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor. Identification of the deletion, amplification, and rearrangement of this gene that are associated with myxoid liposarcoma suggests a role in adipogenesis and mesenchymal differentiation. A gene knock out study of the mouse counterpart demonstrated that this gene is involved in diet-induced obesity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T48166
|
| Target Name |
HMGA2
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
8091
|
| Gene ID |
100271859 (Canis lupus familiaris), 100297155 (Bos taurus), 102149270 (Equus caballus), 111561386 (Felis catus) 15364 (Mus musculus), 717721 (Macaca mulatta), 8091 (Homo sapiens), 84017 (Rattus norvegicus)
|
| Target Alternative Names |
9430083A20Rik,BABL,HMGA2,HMGI-C,HMGIC,High mobility group AT-hook protein 2,High mobility group protein HMGI-C,Hmga2,Hmgic,LIPO,SRS5,STQTL9,pg,pygmy
|
| Uniprot Accession |
P52927,P52926
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Gene Ensembl |
ENSCAFG00845012436, ENSBTAG00000044118, ENSECAG00000040252, ENSMUSG00000056758, ENSG00000149948
|
| Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of HMGA2 cDNA Clones/ORF Plasmid
HMGA2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo8091 | Pre-made Human HMGA2/BABL/LIPO siRNA oligo Duplex | 8091 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo84017 | Pre-made Rat Hmga2/Hmgic siRNA oligo Duplex | 84017 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo15364 | Pre-made Mouse Hmga2/pg/Hmgic siRNA oligo Duplex | 15364 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo717721 | Pre-made Cynomolgus/Rhesus macaque HMGA2 siRNA oligo Duplex | 717721 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo111561386 | Pre-made Cat/Feline HMGA2 siRNA oligo Duplex | 111561386 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100271859 | Pre-made Dog/Canine HMGA2 siRNA oligo Duplex | 100271859 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100297155 | Pre-made Bovines/Cattle HMGA2 siRNA oligo Duplex | 100297155 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo102149270 | Pre-made Equine/Horse HMGA2 siRNA oligo Duplex | 102149270 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
HMGA2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T48166-Ab | Human | Anti-Human HMGA2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T48166-Ab | Rat | Anti-Rat HMGA2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T48166-Ab | Mouse | Anti-Mouse HMGA2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T48166-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque HMGA2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T48166-Ab | Cat/Feline | Anti-Cat/Feline HMGA2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T48166-Ab | Dog/Canine | Anti-Dog/Canine HMGA2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T48166-Ab | Bovines/Cattle | Anti-Bovines/Cattle HMGA2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T48166-Ab | Equine/Horse | Anti-Equine/Horse HMGA2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
HMGA2 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T48166-Ag | Human | Human HMGA2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T48166-Ag | Rat | Rat HMGA2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T48166-Ag | Mouse | Mouse HMGA2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T48166-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque HMGA2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T48166-Ag | Cat/Feline | Cat/Feline HMGA2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T48166-Ag | Dog/Canine | Dog/Canine HMGA2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T48166-Ag | Bovines/Cattle | Bovines/Cattle HMGA2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T48166-Ag | Equine/Horse | Equine/Horse HMGA2 recombinant protein | Mammalian cell | Detail |