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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Introcelluar Protein.
This gene encodes a member of the aurora kinase subfamily of serine/threonine kinases. The genes encoding the other two members of this subfamily are located on chromosomes 19 and 20. These kinases participate in the regulation of alignment and segregation of chromosomes during mitosis and meiosis through association with microtubules. A pseudogene of this gene is located on chromosome 8. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2015]
| Target ID |
GM-T46781
|
| Target Name |
AURKB
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
9212
|
| Gene ID |
100073050 (Equus caballus), 101081264 (Felis catus), 114592 (Rattus norvegicus), 20877 (Mus musculus)
360192 (Bos taurus), 479492 (Canis lupus familiaris), 721955 (Macaca mulatta), 9212 (Homo sapiens)
|
| Target Alternative Names |
AIK2,AIM-1,AIM1,AIRK2,ARK-2,ARK2,AURKB,Aik2,Aim1,Ark2,AurB,Aurkb,Aurora 1,Aurora kinase B,Aurora- and IPL1-like midbody-associated protein 1 (AIM-1),Aurora-related kinase 2),Aurora/IPL1-related kinase 2 (ARK-2,IPL1,PPP1R48,STK-1,STK12,STK5,Serine/threonine-protein kinase 12,Serine/threonine-protein kinase 5,Serine/threonine-protein kinase aurora-B,Stk12,Stk5,aurkb-sv1,aurkb-sv2
|
| Uniprot Accession |
O55099,O70126,Q7YRC6,Q96GD4
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Gene Ensembl |
ENSECAG00000014384, ENSMUSG00000020897, ENSBTAG00000001717, ENSCAFG00845028309, ENSMMUG00000002997, ENSG00000178999
|
| Target Classification |
Kinase, Tumor-associated antigen (TAA)
|
Pre-made viral vector of AURKB cDNA Clones/ORF Plasmid
AURKB siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo9212 | Pre-made Human AURKB/AIK2/AIM1 siRNA oligo Duplex | 9212 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo114592 | Pre-made Rat Aurkb/Aim1/ARK-2 siRNA oligo Duplex | 114592 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo20877 | Pre-made Mouse Aurkb/Aik2/Aim1 siRNA oligo Duplex | 20877 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo721955 | Pre-made Cynomolgus/Rhesus macaque AURKB siRNA oligo Duplex | 721955 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101081264 | Pre-made Cat/Feline AURKB siRNA oligo Duplex | 101081264 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo479492 | Pre-made Dog/Canine AURKB siRNA oligo Duplex | 479492 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo360192 | Pre-made Bovines/Cattle AURKB/AIM-1/ARK-2 siRNA oligo Duplex | 360192 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100073050 | Pre-made Equine/Horse AURKB siRNA oligo Duplex | 100073050 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
AURKB antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T46781-Ab | Human | Anti-Human AURKB monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T46781-Ab | Rat | Anti-Rat AURKB monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T46781-Ab | Mouse | Anti-Mouse AURKB monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T46781-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque AURKB monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T46781-Ab | Cat/Feline | Anti-Cat/Feline AURKB monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T46781-Ab | Dog/Canine | Anti-Dog/Canine AURKB monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T46781-Ab | Bovines/Cattle | Anti-Bovines/Cattle AURKB monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T46781-Ab | Equine/Horse | Anti-Equine/Horse AURKB monoclonal antibody | mab | Therapeutics Target antibody | Detail |
AURKB recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T46781-Ag | Human | Human AURKB recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T46781-Ag | Rat | Rat AURKB recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T46781-Ag | Mouse | Mouse AURKB recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T46781-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque AURKB recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T46781-Ag | Cat/Feline | Cat/Feline AURKB recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T46781-Ag | Dog/Canine | Dog/Canine AURKB recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T46781-Ag | Bovines/Cattle | Bovines/Cattle AURKB recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T46781-Ag | Equine/Horse | Equine/Horse AURKB recombinant protein | Mammalian cell | Detail |
