Recombinant multi-species AURKB protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine AURKB protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the aurora kinase subfamily of serine/threonine kinases. The genes encoding the other two members of this subfamily are located on chromosomes 19 and 20. These kinases participate in the regulation of alignment and segregation of chromosomes during mitosis and meiosis through association with microtubules. A pseudogene of this gene is located on chromosome 8. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2015]
The Alternative Names of target: AIK2,AIM-1,AIM1,AIRK2,ARK-2,ARK2,AURKB,Aik2,Aim1,Ark2,AurB,Aurkb,Aurora 1,Aurora kinase B,Aurora- and IPL1-like midbody-associated protein 1 (AIM-1),Aurora-related kinase 2),Aurora/IPL1-related kinase 2 (ARK-2,IPL1,PPP1R48,STK-1,STK12,STK5,Serine/threonine-protein kinase 12,Serine/threonine-protein kinase 5,Serine/threonine-protein kinase aurora-B,Stk12,Stk5,aurkb-sv1,aurkb-sv2

Target products collectionGo to AURKB products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T46781-Ag-1/ GM-Tg-hg-T46781-Ag-2 Human AURKB protein Human
GM-Tg-rg-T46781-Ag-1/ GM-Tg-rg-T46781-Ag-2 Rat AURKB protein Rat
GM-Tg-mg-T46781-Ag-1/ GM-Tg-mg-T46781-Ag-2 Mouse AURKB protein Mouse
GM-Tg-cynog-T46781-Ag-1/ GM-Tg-cynog-T46781-Ag-2 Cynomolgus/Rhesus macaque AURKB protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T46781-Ag-1/ GM-Tg-felg-T46781-Ag-2 Feline AURKB protein Feline
GM-Tg-cang-T46781-Ag-1/ GM-Tg-cang-T46781-Ag-2 Canine AURKB protein Canine
GM-Tg-bovg-T46781-Ag-1/ GM-Tg-bovg-T46781-Ag-2 Bovine AURKB protein Bovine
GM-Tg-equg-T46781-Ag-1/ GM-Tg-equg-T46781-Ag-2 Equine AURKB protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T46781-Ag-1/ GM-Tg-hg-T46781-Ag-2; GM-Tg-rg-T46781-Ag-1/ GM-Tg-rg-T46781-Ag-2;
GM-Tg-mg-T46781-Ag-1/ GM-Tg-mg-T46781-Ag-2; GM-Tg-cynog-T46781-Ag-1/ GM-Tg-cynog-T46781-Ag-2;
GM-Tg-felg-T46781-Ag-1/ GM-Tg-felg-T46781-Ag-2; GM-Tg-cang-T46781-Ag-1/ GM-Tg-cang-T46781-Ag-2;
GM-Tg-bovg-T46781-Ag-1/ GM-Tg-bovg-T46781-Ag-2; GM-Tg-equg-T46781-Ag-1/ GM-Tg-equg-T46781-Ag-2
Products Name AURKB protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name AURKB
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine AURKB protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.