Explore IL-19/IL19 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Secreted Protein/Potential Cytokines.
The protein encoded by this gene is a cytokine that belongs to the IL10 cytokine subfamily. This cytokine is found to be preferentially expressed in monocytes. It can bind the IL20 receptor complex and lead to the activation of the signal transducer and activator of transcription 3 (STAT3). A similar cytokine in mouse is reported to up-regulate the expression of IL6 and TNF-alpha and induce apoptosis, which suggests a role of this cytokine in inflammatory responses. Alternatively spliced transcript variants encoding the distinct isoforms have been described. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T44584
|
| Target Name |
IL-19/IL19
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
29949
|
| Gene ID |
100055588 (Equus caballus), 101090582 (Felis catus), 29949 (Homo sapiens), 329244 (Mus musculus) 490265 (Canis lupus familiaris), 527634 (Bos taurus), 681145 (Rattus norvegicus), 694806 (Macaca mulatta)
|
| Target Alternative Names |
IL-10C,IL-19,IL19,Il19,Interleukin-19,MDA1,Melanoma differentiation-associated protein-like protein,NG.1,ZMDA1
|
| Uniprot Accession |
Q9UHD0,Q8CJ70
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Therapeutics Target, Cytokine Target
|
| Disease from KEGG |
Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine receptor, JAK-STAT signaling pathway
|
| Gene Ensembl |
ENSG00000142224, ENSMUSG00000016524, ENSCAFG00845001334, ENSBTAG00000006692, ENSMMUG00000023570
|
Pre-made viral vector of IL-19/IL19 cDNA Clones/ORF Plasmid
IL-19/IL19 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo29949 | Pre-made Human IL19/MDA1/NG.1 siRNA oligo Duplex | 29949 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo681145 | Pre-made Rat Il19 siRNA oligo Duplex | 681145 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo329244 | Pre-made Mouse Il19 siRNA oligo Duplex | 329244 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo694806 | Pre-made Cynomolgus/Rhesus macaque IL19 siRNA oligo Duplex | 694806 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101090582 | Pre-made Cat/Feline IL19 siRNA oligo Duplex | 101090582 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo490265 | Pre-made Dog/Canine IL19 siRNA oligo Duplex | 490265 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo527634 | Pre-made Bovines/Cattle IL19 siRNA oligo Duplex | 527634 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100055588 | Pre-made Equine/Horse IL19 siRNA oligo Duplex | 100055588 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
IL-19/IL19 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T44584-Ab | Human | Anti-Human IL-19/IL19 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-rg-T44584-Ab | Rat | Anti-Rat IL-19/IL19 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-mg-T44584-Ab | Mouse | Anti-Mouse IL-19/IL19 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-T44584-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque IL-19/IL19 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-felg-T44584-Ab | Cat/Feline | Anti-Cat/Feline IL-19/IL19 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cang-T44584-Ab | Dog/Canine | Anti-Dog/Canine IL-19/IL19 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-T44584-Ab | Bovines/Cattle | Anti-Bovines/Cattle IL-19/IL19 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-equg-T44584-Ab | Equine/Horse | Anti-Equine/Horse IL-19/IL19 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
IL-19/IL19 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T44584-Ag | Human | Human IL-19/IL19 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T44584-Ag | Rat | Rat IL-19/IL19 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T44584-Ag | Mouse | Mouse IL-19/IL19 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T44584-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque IL-19/IL19 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T44584-Ag | Cat/Feline | Cat/Feline IL-19/IL19 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T44584-Ag | Dog/Canine | Dog/Canine IL-19/IL19 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T44584-Ag | Bovines/Cattle | Bovines/Cattle IL-19/IL19 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T44584-Ag | Equine/Horse | Equine/Horse IL-19/IL19 recombinant protein | Mammalian cell | Detail |