Recombinant multi-species IL-19/IL19 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine IL-19/IL19 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a cytokine that belongs to the IL10 cytokine subfamily. This cytokine is found to be preferentially expressed in monocytes. It can bind the IL20 receptor complex and lead to the activation of the signal transducer and activator of transcription 3 (STAT3). A similar cytokine in mouse is reported to up-regulate the expression of IL6 and TNF-alpha and induce apoptosis, which suggests a role of this cytokine in inflammatory responses. Alternatively spliced transcript variants encoding the distinct isoforms have been described. [provided by RefSeq, Jul 2008]
The Alternative Names of target: IL-10C,IL-19,IL19,Il19,Interleukin-19,MDA1,Melanoma differentiation-associated protein-like protein,NG.1,ZMDA1

Target products collectionGo to IL-19/IL19 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T44584-Ag-1/ GM-Tg-hg-T44584-Ag-2 Human IL-19/IL19 protein Human
GM-Tg-rg-T44584-Ag-1/ GM-Tg-rg-T44584-Ag-2 Rat IL-19/IL19 protein Rat
GM-Tg-mg-T44584-Ag-1/ GM-Tg-mg-T44584-Ag-2 Mouse IL-19/IL19 protein Mouse
GM-Tg-cynog-T44584-Ag-1/ GM-Tg-cynog-T44584-Ag-2 Cynomolgus/Rhesus macaque IL-19/IL19 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T44584-Ag-1/ GM-Tg-felg-T44584-Ag-2 Feline IL-19/IL19 protein Feline
GM-Tg-cang-T44584-Ag-1/ GM-Tg-cang-T44584-Ag-2 Canine IL-19/IL19 protein Canine
GM-Tg-bovg-T44584-Ag-1/ GM-Tg-bovg-T44584-Ag-2 Bovine IL-19/IL19 protein Bovine
GM-Tg-equg-T44584-Ag-1/ GM-Tg-equg-T44584-Ag-2 Equine IL-19/IL19 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T44584-Ag-1/ GM-Tg-hg-T44584-Ag-2; GM-Tg-rg-T44584-Ag-1/ GM-Tg-rg-T44584-Ag-2;
GM-Tg-mg-T44584-Ag-1/ GM-Tg-mg-T44584-Ag-2; GM-Tg-cynog-T44584-Ag-1/ GM-Tg-cynog-T44584-Ag-2;
GM-Tg-felg-T44584-Ag-1/ GM-Tg-felg-T44584-Ag-2; GM-Tg-cang-T44584-Ag-1/ GM-Tg-cang-T44584-Ag-2;
GM-Tg-bovg-T44584-Ag-1/ GM-Tg-bovg-T44584-Ag-2; GM-Tg-equg-T44584-Ag-1/ GM-Tg-equg-T44584-Ag-2
Products Name IL-19/IL19 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name IL-19/IL19
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine IL-19/IL19 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.