Explore Livin/BIRC7/ML-IAP gene products and cross-species
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Target
sublocation: Introcelluar Protein.
This gene encodes a member of the inhibitor of apoptosis protein (IAP) family, and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Elevated levels of the encoded protein may be associated with cancer progression and play a role in chemotherapy sensitivity. Alternative splicing results in multiple transcript variants [provided by RefSeq, Jul 2013]
| Target ID |
GM-T42247
|
| Target Name |
Livin/BIRC7/ML-IAP
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
79444
|
| Gene ID |
100147373 (Equus caballus), 101080371 (Felis catus), 296468 (Rattus norvegicus), 329581 (Mus musculus)
485969 (Canis lupus familiaris), 514508 (Bos taurus), 697671 (Macaca mulatta), 79444 (Homo sapiens)
|
| Target Alternative Names |
BIRC7,Birc7,RGD1562883,KIAP,Livin,ML-IAP,E130019N06,LIVIN,MLIAP,RNF50
|
| Uniprot Accession |
A2AWP0,Q96CA5
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Disease from KEGG |
Apoptosis - multiple species, Toxoplasmosis, Pathways in cancer, Small cell lung cancer
|
| Gene Ensembl |
ENSECAG00000020286, ENSMUSG00000038840, ENSBTAG00000004911, ENSMMUG00000009229, ENSG00000101197
|
| Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of Livin/BIRC7/ML-IAP cDNA Clones/ORF Plasmid
Livin/BIRC7/ML-IAP siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo79444 | Pre-made Human BIRC7/KIAP/LIVIN siRNA oligo Duplex | 79444 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo296468 | Pre-made Rat Birc7/RGD1562883 siRNA oligo Duplex | 296468 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo329581 | Pre-made Mouse Birc7/KIAP/Livin siRNA oligo Duplex | 329581 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo697671 | Pre-made Cynomolgus/Rhesus macaque BIRC7 siRNA oligo Duplex | 697671 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101080371 | Pre-made Cat/Feline BIRC7 siRNA oligo Duplex | 101080371 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo485969 | Pre-made Dog/Canine BIRC7 siRNA oligo Duplex | 485969 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo514508 | Pre-made Bovines/Cattle BIRC7 siRNA oligo Duplex | 514508 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100147373 | Pre-made Equine/Horse BIRC7 siRNA oligo Duplex | 100147373 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
Livin/BIRC7/ML-IAP antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T42247-Ab | Human | Anti-Human Livin/BIRC7/ML-IAP monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T42247-Ab | Rat | Anti-Rat Livin/BIRC7/ML-IAP monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T42247-Ab | Mouse | Anti-Mouse Livin/BIRC7/ML-IAP monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T42247-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque Livin/BIRC7/ML-IAP monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T42247-Ab | Cat/Feline | Anti-Cat/Feline Livin/BIRC7/ML-IAP monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T42247-Ab | Dog/Canine | Anti-Dog/Canine Livin/BIRC7/ML-IAP monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T42247-Ab | Bovines/Cattle | Anti-Bovines/Cattle Livin/BIRC7/ML-IAP monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T42247-Ab | Equine/Horse | Anti-Equine/Horse Livin/BIRC7/ML-IAP monoclonal antibody | mab | Therapeutics Target antibody | Detail |
Livin/BIRC7/ML-IAP recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T42247-Ag | Human | Human Livin/BIRC7/ML-IAP recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T42247-Ag | Rat | Rat Livin/BIRC7/ML-IAP recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T42247-Ag | Mouse | Mouse Livin/BIRC7/ML-IAP recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T42247-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque Livin/BIRC7/ML-IAP recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T42247-Ag | Cat/Feline | Cat/Feline Livin/BIRC7/ML-IAP recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T42247-Ag | Dog/Canine | Dog/Canine Livin/BIRC7/ML-IAP recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T42247-Ag | Bovines/Cattle | Bovines/Cattle Livin/BIRC7/ML-IAP recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T42247-Ag | Equine/Horse | Equine/Horse Livin/BIRC7/ML-IAP recombinant protein | Mammalian cell | Detail |
