Recombinant multi-species Livin/BIRC7/ML-IAP protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine Livin/BIRC7/ML-IAP protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the inhibitor of apoptosis protein (IAP) family, and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Elevated levels of the encoded protein may be associated with cancer progression and play a role in chemotherapy sensitivity. Alternative splicing results in multiple transcript variants [provided by RefSeq, Jul 2013]
The Alternative Names of target: Livin, BIRC7, ML-IAP,Baculoviral IAP repeat-containing protein 7,Kidney inhibitor of apoptosis protein (KIAP), Livin, Melanoma inhibitor of apoptosis protein (ML-IAP), RING finger protein 50, RING-type E3 ubiquitin transferase BIRC7,KIAP,LIVIN,MLIAP,RNF50,ML-IAP

Target products collectionGo to Livin/BIRC7/ML-IAP products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T42247-Ab-1/ GM-Tg-hg-T42247-Ab-2 Human Livin/BIRC7/ML-IAP protein Human
GM-Tg-rg-T42247-Ab-1/ GM-Tg-rg-T42247-Ab-2 Rat Livin/BIRC7/ML-IAP protein Rat
GM-Tg-mg-T42247-Ab-1/ GM-Tg-mg-T42247-Ab-2 Mouse Livin/BIRC7/ML-IAP protein Mouse
GM-Tg-cynog-T42247-Ab-1/ GM-Tg-cynog-T42247-Ab-2 Cynomolgus/Rhesus macaque Livin/BIRC7/ML-IAP monoclonal antibody Cynomolgus/ Rhesus macaque
GM-Tg-felg-T42247-Ab-1/ GM-Tg-felg-T42247-Ab-2 Feline Livin/BIRC7/ML-IAP protein Feline
GM-Tg-cang-T42247-Ab-1/ GM-Tg-cang-T42247-Ab-2 Canine Livin/BIRC7/ML-IAP protein Canine
GM-Tg-bovg-T42247-Ab-1/ GM-Tg-bovg-T42247-Ab-2 Bovine Livin/BIRC7/ML-IAP protein Bovine
GM-Tg-equg-T42247-Ab-1/ GM-Tg-equg-T42247-Ab-2 Equine Livin/BIRC7/ML-IAP protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T42247-Ab-1/ GM-Tg-hg-T42247-Ab-2; GM-Tg-rg-T42247-Ab-1/ GM-Tg-rg-T42247-Ab-2;
GM-Tg-mg-T42247-Ab-1/ GM-Tg-mg-T42247-Ab-2; GM-Tg-cynog-T42247-Ab-1/ GM-Tg-cynog-T42247-Ab-2;
GM-Tg-felg-T42247-Ab-1/ GM-Tg-felg-T42247-Ab-2; GM-Tg-cang-T42247-Ab-1/ GM-Tg-cang-T42247-Ab-2;
GM-Tg-bovg-T42247-Ab-1/ GM-Tg-bovg-T42247-Ab-2; GM-Tg-equg-T42247-Ab-1/ GM-Tg-equg-T42247-Ab-2
Products Name Livin/BIRC7/ML-IAP protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name Livin/BIRC7/ML-IAP
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine Livin/BIRC7/ML-IAP protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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