Explore PF4 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a member of the CXC chemokine family. This chemokine is released from the alpha granules of activated platelets in the form of a homotetramer which has high affinity for heparin and is involved in platelet aggregation. This protein is chemotactic for numerous other cell type and also functions as an inhibitor of hematopoiesis, angiogenesis and T-cell function. The protein also exhibits antimicrobial activity against Plasmodium falciparum. [provided by RefSeq, Oct 2014]
| Target ID |
GM-T30827
|
| Target Name |
PF4
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
5196
|
| Gene ID |
100630489 (Equus caballus), 360918 (Rattus norvegicus), 507790 (Bos taurus), 5196 (Homo sapiens)
56744 (Mus musculus), 703451 (Macaca mulatta)
|
| Target Alternative Names |
LOC100630489,Pf4,PF4,PF-4,Pf4a,Cxcl4,RATPF4A,CXCL4,SCYB4,Scyb4
|
| Uniprot Accession |
P06765,P02777,P02776,Q9Z126
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Therapeutics Target, Cytokine Target
|
| Disease |
cancer
|
| Disease from KEGG |
Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine receptor, Chemokine signaling pathway
|
| Gene Ensembl |
ENSECAG00000012560, ENSG00000163737, ENSMUSG00000029373, ENSMMUG00000058452
|
| Target Classification |
|
Pre-made viral vector of PF4 cDNA Clones/ORF Plasmid
PF4 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo5196 | Pre-made Human PF4/PF-4/CXCL4 siRNA oligo Duplex | 5196 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo360918 | Pre-made Rat Pf4/PF-4/Pf4a siRNA oligo Duplex | 360918 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo56744 | Pre-made Mouse Pf4/Cxcl4/Scyb4 siRNA oligo Duplex | 56744 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo703451 | Pre-made Cynomolgus/Rhesus macaque PF4 siRNA oligo Duplex | 703451 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo507790 | Pre-made Bovines/Cattle PF4 siRNA oligo Duplex | 507790 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100630489 | Pre-made Equine/Horse LOC100630489/PF4 siRNA oligo Duplex | 100630489 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
PF4 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T30827-Ab | Human | Anti-Human PF4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-rg-T30827-Ab | Rat | Anti-Rat PF4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-mg-T30827-Ab | Mouse | Anti-Mouse PF4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-T30827-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque PF4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-T30827-Ab | Bovines/Cattle | Anti-Bovines/Cattle PF4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-equg-T30827-Ab | Equine/Horse | Anti-Equine/Horse PF4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
PF4 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T30827-Ag | Human | Human PF4 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T30827-Ag | Rat | Rat PF4 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T30827-Ag | Mouse | Mouse PF4 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T30827-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque PF4 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T30827-Ag | Bovines/Cattle | Bovines/Cattle PF4 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T30827-Ag | Equine/Horse | Equine/Horse PF4 recombinant protein | Mammalian cell | Detail |
