Recombinant multi-species PF4 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PF4 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the CXC chemokine family. This chemokine is released from the alpha granules of activated platelets in the form of a homotetramer which has high affinity for heparin and is involved in platelet aggregation. This protein is chemotactic for numerous other cell type and also functions as an inhibitor of hematopoiesis, angiogenesis and T-cell function. The protein also exhibits antimicrobial activity against Plasmodium falciparum. [provided by RefSeq, Oct 2014]
The Alternative Names of target: PF4,Platelet factor 4,PF-4,C-X-C motif chemokine 4, Iroplact, Oncostatin-A,PF-4,CXCL4,SCYB4

Target products collectionGo to PF4 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T30827-Ab-1/ GM-Tg-hg-T30827-Ab-2 Human PF4 protein Human
GM-Tg-rg-T30827-Ab-1/ GM-Tg-rg-T30827-Ab-2 Rat PF4 protein Rat
GM-Tg-mg-T30827-Ab-1/ GM-Tg-mg-T30827-Ab-2 Mouse PF4 protein Mouse
GM-Tg-cynog-T30827-Ab-1/ GM-Tg-cynog-T30827-Ab-2 Cynomolgus/Rhesus macaque PF4 monoclonal antibody Cynomolgus/ Rhesus macaque
GM-Tg-felg-T30827-Ab-1/ GM-Tg-felg-T30827-Ab-2 Feline PF4 protein Feline
GM-Tg-cang-T30827-Ab-1/ GM-Tg-cang-T30827-Ab-2 Canine PF4 protein Canine
GM-Tg-bovg-T30827-Ab-1/ GM-Tg-bovg-T30827-Ab-2 Bovine PF4 protein Bovine
GM-Tg-equg-T30827-Ab-1/ GM-Tg-equg-T30827-Ab-2 Equine PF4 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T30827-Ab-1/ GM-Tg-hg-T30827-Ab-2; GM-Tg-rg-T30827-Ab-1/ GM-Tg-rg-T30827-Ab-2;
GM-Tg-mg-T30827-Ab-1/ GM-Tg-mg-T30827-Ab-2; GM-Tg-cynog-T30827-Ab-1/ GM-Tg-cynog-T30827-Ab-2;
GM-Tg-felg-T30827-Ab-1/ GM-Tg-felg-T30827-Ab-2; GM-Tg-cang-T30827-Ab-1/ GM-Tg-cang-T30827-Ab-2;
GM-Tg-bovg-T30827-Ab-1/ GM-Tg-bovg-T30827-Ab-2; GM-Tg-equg-T30827-Ab-1/ GM-Tg-equg-T30827-Ab-2
Products Name PF4 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name PF4
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PF4 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.