Explore IL-13/IL13 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T29143
|
| Target Name |
IL-13/IL13
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
3596
|
| Gene ID |
100034113 (Equus caballus), 101084678 (Felis catus), 116553 (Rattus norvegicus), 16163 (Mus musculus)
281247 (Bos taurus), 3596 (Homo sapiens), 442990 (Canis lupus familiaris), 574325 (Macaca mulatta)
|
| Target Alternative Names |
IL-13,IL13,Il-13,Il13,Interleukin-13,P600
|
| Uniprot Accession |
P42203,P20109,Q9XSV9,P35225,Q9N0W9,Q864V6
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Therapeutics Target, Immuno-oncology Target, INN Index
|
| Disease |
cancer, Breast Cancer, asthma, Malignant neoplasm of bladder
|
| Disease from KEGG |
Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway, IL-17 signaling pathway, Th1 and Th2 cell differentiation, Fc epsilon RI signaling pathway, Pathways in cancer, Asthma, Inflammatory bowel disease
|
| Gene Ensembl |
ENSECAG00000009732, ENSMUSG00000020383, ENSBTAG00000015953, ENSG00000169194, ENSCAFG00845010953, ENSMMUG00000003131
|
| Target Classification |
Checkpoint-Immuno Oncology
|
Pre-made viral vector of IL-13/IL13 cDNA Clones/ORF Plasmid
IL-13/IL13 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3596 | Pre-made Human IL13/P600/IL-13 siRNA oligo Duplex | 3596 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo116553 | Pre-made Rat Il13 siRNA oligo Duplex | 116553 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo16163 | Pre-made Mouse Il13/Il-13 siRNA oligo Duplex | 16163 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo574325 | Pre-made Cynomolgus/Rhesus macaque IL13 siRNA oligo Duplex | 574325 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101084678 | Pre-made Cat/Feline IL13 siRNA oligo Duplex | 101084678 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo442990 | Pre-made Dog/Canine IL13 siRNA oligo Duplex | 442990 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281247 | Pre-made Bovines/Cattle IL13 siRNA oligo Duplex | 281247 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100034113 | Pre-made Equine/Horse IL13/IL-13 siRNA oligo Duplex | 100034113 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
IL-13/IL13 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T29143-Ab | Human | Anti-Human IL-13/IL13 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T29143-Ab | Rat | Anti-Rat IL-13/IL13 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T29143-Ab | Mouse | Anti-Mouse IL-13/IL13 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T29143-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque IL-13/IL13 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T29143-Ab | Cat/Feline | Anti-Cat/Feline IL-13/IL13 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T29143-Ab | Dog/Canine | Anti-Dog/Canine IL-13/IL13 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T29143-Ab | Bovines/Cattle | Anti-Bovines/Cattle IL-13/IL13 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T29143-Ab | Equine/Horse | Anti-Equine/Horse IL-13/IL13 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
IL-13/IL13 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T29143-Ag | Human | Human IL-13/IL13 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T29143-Ag | Rat | Rat IL-13/IL13 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T29143-Ag | Mouse | Mouse IL-13/IL13 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T29143-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque IL-13/IL13 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T29143-Ag | Cat/Feline | Cat/Feline IL-13/IL13 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T29143-Ag | Dog/Canine | Dog/Canine IL-13/IL13 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T29143-Ag | Bovines/Cattle | Bovines/Cattle IL-13/IL13 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T29143-Ag | Equine/Horse | Equine/Horse IL-13/IL13 recombinant protein | Mammalian cell | Detail |
