Explore S100A8 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and as a cytokine. Altered expression of this protein is associated with the disease cystic fibrosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2016]
| Target ID |
GM-T27402
|
| Target Name |
S100A8
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
6279
|
| Gene ID |
100061766 (Equus caballus), 101084164 (Felis catus), 116547 (Rattus norvegicus), 20201 (Mus musculus) 490461 (Canis lupus familiaris), 616818 (Bos taurus), 6279 (Homo sapiens), 714740 (Macaca mulatta)
|
| Target Alternative Names |
60B8AG,60B8Ag,B8Ag,CAGA,CFAG,CFAg,CGLA,CP-10,Caga,Calgranulin-A,Calprotectin L1L subunit,Cystic fibrosis antigen (CFAG),L1Ag,Leukocyte L1 complex light chain,MA387,MIF,MRP8,Migration inhibitory factor-related protein 8 (MRP-8,Mrp8,NIF,P8,Protein S100-A8,S100 calcium-binding protein A8,S100-A8,S100A8,S100a8,Urinary stone protein band A,p8,p8)
|
| Uniprot Accession |
P50115,P27005,P28782,P05109
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Diagnostics Biomarker
|
| Disease |
cancer, Acute appendicitis, Congenital occlusion of ureteropelvic junction, Contact with and (suspected) exposure to environmental tobacco smoke (acute) (chronic), Malignant neoplasm of bladder
|
| Disease from KEGG |
IL-17 signaling pathway
|
| Gene Ensembl |
ENSMUSG00000056054, ENSCAFG00845002217, ENSG00000143546, ENSMMUG00000044778
|
Pre-made viral vector of S100A8 cDNA Clones/ORF Plasmid
S100A8 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo6279 | Pre-made Human S100A8/P8/MIF siRNA oligo Duplex | 6279 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo116547 | Pre-made Rat S100a8/Mrp8 siRNA oligo Duplex | 116547 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo20201 | Pre-made Mouse S100a8/p8/B8Ag siRNA oligo Duplex | 20201 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo714740 | Pre-made Cynomolgus/Rhesus macaque S100A8 siRNA oligo Duplex | 714740 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101084164 | Pre-made Cat/Feline S100A8 siRNA oligo Duplex | 101084164 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo490461 | Pre-made Dog/Canine S100A8 siRNA oligo Duplex | 490461 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo616818 | Pre-made Bovines/Cattle S100A8 siRNA oligo Duplex | 616818 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100061766 | Pre-made Equine/Horse S100A8 siRNA oligo Duplex | 100061766 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
S100A8 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T27402-Ab | Human | Anti-Human S100A8 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Diagnostic target antibody | Detail |
| GM-Tg-rg-T27402-Ab | Rat | Anti-Rat S100A8 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Diagnostic target antibody | Detail |
| GM-Tg-mg-T27402-Ab | Mouse | Anti-Mouse S100A8 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Diagnostic target antibody | Detail |
| GM-Tg-cynog-T27402-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque S100A8 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Diagnostic target antibody | Detail |
| GM-Tg-felg-T27402-Ab | Cat/Feline | Anti-Cat/Feline S100A8 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Diagnostic target antibody | Detail |
| GM-Tg-cang-T27402-Ab | Dog/Canine | Anti-Dog/Canine S100A8 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Diagnostic target antibody | Detail |
| GM-Tg-bovg-T27402-Ab | Bovines/Cattle | Anti-Bovines/Cattle S100A8 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Diagnostic target antibody | Detail |
| GM-Tg-equg-T27402-Ab | Equine/Horse | Anti-Equine/Horse S100A8 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Diagnostic target antibody | Detail |
S100A8 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T27402-Ag | Human | Human S100A8 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T27402-Ag | Rat | Rat S100A8 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T27402-Ag | Mouse | Mouse S100A8 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T27402-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque S100A8 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T27402-Ag | Cat/Feline | Cat/Feline S100A8 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T27402-Ag | Dog/Canine | Dog/Canine S100A8 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T27402-Ag | Bovines/Cattle | Bovines/Cattle S100A8 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T27402-Ag | Equine/Horse | Equine/Horse S100A8 VLP (virus-like particle) | HEK293 | Products Developing |