GAD1 Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore GAD1 gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Introcelluar Protein.
This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form. [provided by RefSeq, Jul 2008]

Target ID GM-T26900
Target Name GAD1
Gene Group ldentifer
(Target Gene ID in Homo species)
2571
Gene ID 100052860 (Equus caballus), 14415 (Mus musculus), 24379 (Rattus norvegicus), 2571 (Homo sapiens)
478794 (Canis lupus familiaris), 493699 (Felis catus), 517552 (Bos taurus), 613030 (Macaca mulatta)
Target Alternative Names 67 kDa glutamic acid decarboxylase (GAD-67),CPSQ1,DEE89,EP10,GAD,GAD1,GAD67,Gad-1,Gad1,Gad67,Glutamate decarboxylase 1,Glutamate decarboxylase 67 kDa isoform,SCP
Uniprot Accession P48318,P18088,Q99259,A0PA85,P14748,Q0VCA1
Protein Sub-location Introcelluar Protein
Category Therapeutics Target
Disease from KEGG Metabolic pathways, GABAergic synapse, Type I diabetes mellitus
Gene Ensembl ENSECAG00000012405, ENSMUSG00000070880, ENSG00000128683, ENSCAFG00845025996, ENSBTAG00000007258, ENSMMUG00000015198


Pre-made viral vector of GAD1 cDNA Clones/ORF Plasmid

Cat No.Product NameNMIDGeneIDSpeciesTypeMarkerFusion TagPromoterDetail
pGMAP000105Human GAD1 Adenovirus plasmidBC0028152571HumanAdenovirus plasmidGFP3xflag (C-Terminal)EF1Detail
vGMAP000105Human GAD1 Adenovirus particleBC0028152571HumanAdenovirus particleGFP3xflag (C-Terminal)EF1Detail
pGMLPm003027Mouse Gad1/EP10/Gad-1 Lentivirus plasmidNM_008077.514415MouseLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
vGMLPm003027Mouse Gad1/EP10/Gad-1 Lentivirus particleNM_008077.514415MouseLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail


GAD1 siRNA/miRNA/oligo for RNA interfence (RNAi)

Cat No.Product NameGeneIDSpeciesGradeDetail
pGMoligo2571Pre-made Human GAD1/GAD/SCP siRNA oligo Duplex2571HumanIn-vitro grade; in-vivo gradeDetail
pGMoligo24379Pre-made Rat Gad1/Gad67 siRNA oligo Duplex24379RatIn-vitro grade; in-vivo gradeDetail
pGMoligo14415Pre-made Mouse Gad1/EP10/Gad-1 siRNA oligo Duplex14415MouseIn-vitro grade; in-vivo gradeDetail
pGMoligo613030Pre-made Cynomolgus/Rhesus macaque GAD1/GAD67 siRNA oligo Duplex613030Cynomolgus/Rhesus macaqueIn-vitro grade; in-vivo gradeDetail
pGMoligo493699Pre-made Cat/Feline GAD1/GAD67 siRNA oligo Duplex493699Cat/FelineIn-vitro grade; in-vivo gradeDetail
pGMoligo478794Pre-made Dog/Canine GAD1/GAD67 siRNA oligo Duplex478794Dog/CanineIn-vitro grade; in-vivo gradeDetail
pGMoligo517552Pre-made Bovines/Cattle GAD1 siRNA oligo Duplex517552Bovines/CattleIn-vitro grade; in-vivo gradeDetail
pGMoligo100052860Pre-made Equine/Horse GAD1 siRNA oligo Duplex100052860Equine/HorseIn-vitro grade; in-vivo gradeDetail


GAD1 antibody/GMab

Cat No.SpeciesAntibody NameFormatClassified by tagDetail
GM-Tg-hg-T26900-AbHumanAnti-Human GAD1 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-rg-T26900-AbRatAnti-Rat GAD1 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-mg-T26900-AbMouseAnti-Mouse GAD1 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-cynog-T26900-AbCynomolgus/Rhesus macaqueAnti-Cynomolgus/Rhesus macaque GAD1 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-felg-T26900-AbCat/FelineAnti-Cat/Feline GAD1 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-cang-T26900-AbDog/CanineAnti-Dog/Canine GAD1 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-bovg-T26900-AbBovines/CattleAnti-Bovines/Cattle GAD1 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-equg-T26900-AbEquine/HorseAnti-Equine/Horse GAD1 monoclonal antibodymabTherapeutics Target antibodyDetail


GAD1 recombinant protein

Cat No.SpeciesAntigen NameExpression PlatformDetail
GM-Tg-hg-T26900-AgHumanHuman GAD1 recombinant proteinMammalian cellDetail
GM-Tg-rg-T26900-AgRatRat GAD1 recombinant proteinMammalian cellDetail
GM-Tg-mg-T26900-AgMouseMouse GAD1 recombinant proteinMammalian cellDetail
GM-Tg-cynog-T26900-AgCynomolgus/Rhesus macaqueCynomolgus/Rhesus macaque GAD1 recombinant proteinMammalian cellDetail
GM-Tg-felg-T26900-AgCat/FelineCat/Feline GAD1 recombinant proteinMammalian cellDetail
GM-Tg-cang-T26900-AgDog/CanineDog/Canine GAD1 recombinant proteinMammalian cellDetail
GM-Tg-bovg-T26900-AgBovines/CattleBovines/Cattle GAD1 recombinant proteinMammalian cellDetail
GM-Tg-equg-T26900-AgEquine/HorseEquine/Horse GAD1 recombinant proteinMammalian cellDetail