APOE Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore APOE gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Transmembrane Protein.
The protein encoded by this gene is a major apoprotein of the chylomicron. It binds to a specific liver and peripheral cell receptor, and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. This gene maps to chromosome 19 in a cluster with the related apolipoprotein C1 and C2 genes. Mutations in this gene result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. [provided by RefSeq, Jun 2016]

Target ID	GM-T21689
Target Name	APOE
Gene Group ldentifer （Target Gene ID in Homo species)	348
Gene ID	100065481 (Equus caballus), 101086769 (Felis catus), 11816 (Mus musculus), 25728 (Rattus norvegicus) 281004 (Bos taurus), 348 (Homo sapiens), 476438 (Canis lupus familiaris), 714623 (Macaca mulatta)
Target Alternative Names	AD2,APO-E,APOE,APOEA,Apo-E,ApoE4,Apoe,Apolipoprotein E,LDLCQ5,LPG
Uniprot Accession	P08226,P02650,Q03247,P02649,P18649,Q28502
Protein Sub-location	Transmembrane Protein
Category	Therapeutics Target, Diagnostics Biomarker
Disease	cancer, Type 1 diabetes mellitus, Alzheimer's Disease, Breast neoplasms, Dent disease, Malignant neoplasm of bladder, Other diseases of intestines (K55-K64)
Disease from KEGG	Cholesterol metabolism, Alzheimer disease
Gene Ensembl	ENSECAG00000008236, ENSMUSG00000002985, ENSBTAG00000010123, ENSG00000130203, ENSCAFG00845006705, ENSMMUG00000014305

Pre-made viral vector of APOE cDNA Clones/ORF Plasmid

Cat No.	Product Name	NMID	GeneID	Species	Type	Marker	Fusion Tag	Promoter	Detail
pGMLP001912	Human APOE/AD2/APO-E Lentivirus plasmid	NM_000041.3	348	Human	Lentivirus plasmid	ZsGreen	3xflag (C-Terminal)	CMV	Detail
vGMLP001912	Human APOE/AD2/APO-E Lentivirus particle	NM_000041.3	348	Human	Lentivirus particle	ZsGreen	3xflag (C-Terminal)	CMV	Detail
vGMAAV001436	Human APOE/AD2/APO-E Adeno-associate virus(AAV) particle	NM_000041.4	348	Human	Adeno-associate virus(AAV) particle	ZsGreen	3xflag (C-Terminal)	TBG	Detail
vGMAAV000334	Human APOE/AD2/APO-E Adeno-associate virus(AAV) particle	NM_000041.3	348	Human	Adeno-associate virus(AAV) particle	GFP	3xflag (C-Terminal)	hSyn	Detail
vGMLV001748	Human APOE/AD2/APO-E Lentivirus particle	NM_000041.3	348	Human	Lentivirus particle	mCherry	3xflag (C-Terminal)	CMV	Detail
pGMPC004755	Human APOE/AD2/APO-E Mammalian (Non-Viral Vector) plasmid	NM_000041.4	348	Human	Mammalian (Non-Viral Vector) plasmid	Null	HA (C-Terminal)	CMV	Detail
pGMAAV000334	Human APOE/AD2/APO-E Adeno-associate virus(AAV) plasmid	NM_000041.3	348	Human	Adeno-associate virus(AAV) plasmid	GFP	3xflag (C-Terminal)	hSyn	Detail
pGMAAV001436	Human APOE/AD2/APO-E Adeno-associate virus(AAV) plasmid	NM_000041.4	348	Human	Adeno-associate virus(AAV) plasmid	ZsGreen	3xflag (C-Terminal)	TBG	Detail
pGMLV001748	Human APOE/AD2/APO-E Lentivirus plasmid	NM_000041.3	348	Human	Lentivirus plasmid	mCherry	3xflag (C-Terminal)	CMV	Detail
pGMLPm000901	Mouse Apoe/AI255918/Apo-E Lentivirus plasmid	NM_009696	11816	Mouse	Lentivirus plasmid	ZsGreen	3xflag (C-Terminal)	CMV	Detail
pGMPC001709	Mouse Apoe/Apo-E Mammalian (Non-Viral Vector) plasmid	NM_009696.4	11816	Mouse	Mammalian (Non-Viral Vector) plasmid	Null	3xflag (C-Terminal)	CMV	Detail
pGMLV001747	Mouse Apoe/AI255918/Apo-E Lentivirus plasmid	NM_009696	11816	Mouse	Lentivirus plasmid	mCherry	3xflag (C-Terminal)	CMV	Detail
pGMAAV000545	Mouse Apoe/AI255918/Apo-E Adeno-associate virus(AAV) plasmid	NM_009696.4	11816	Mouse	Adeno-associate virus(AAV) plasmid	ZsGreen	3xflag (C-Terminal)	CMV	Detail
vGMLV001747	Mouse Apoe/AI255918/Apo-E Lentivirus particle	NM_009696	11816	Mouse	Lentivirus particle	mCherry	3xflag (C-Terminal)	CMV	Detail
vGMLV002187	Mouse Apoe/Apo-E Lentivirus particle	NM_009696	11816	Mouse	Lentivirus particle	mCherry	3xflag (C-Terminal)	CMV	Detail
pGMLV002187	Mouse Apoe/Apo-E Lentivirus plasmid	NM_009696	11816	Mouse	Lentivirus plasmid	mCherry	3xflag (C-Terminal)	CMV	Detail
vGMAAV000545	Mouse Apoe/AI255918/Apo-E Adeno-associate virus(AAV) particle	NM_009696.4	11816	Mouse	Adeno-associate virus(AAV) particle	ZsGreen	3xflag (C-Terminal)	CMV	Detail
vGMLPm000901	Mouse Apoe/AI255918/Apo-E Lentivirus particle	NM_009696	11816	Mouse	Lentivirus particle	ZsGreen	3xflag (C-Terminal)	CMV	Detail

APOE siRNA/miRNA/oligo for RNA interfence (RNAi)

Cat No.	Product Name	GeneID	Species	Grade	Detail
pGMoligo348	Pre-made Human APOE/AD2/LPG siRNA oligo Duplex	348	Human	In-vitro grade; in-vivo grade	Detail
pGMoligo25728	Pre-made Rat Apoe/APOEA siRNA oligo Duplex	25728	Rat	In-vitro grade; in-vivo grade	Detail
pGMoligo11816	Pre-made Mouse Apoe/Apo-E siRNA oligo Duplex	11816	Mouse	In-vitro grade; in-vivo grade	Detail
pGMoligo714623	Pre-made Cynomolgus/Rhesus macaque APOE/Apo-E siRNA oligo Duplex	714623	Cynomolgus/Rhesus macaque	In-vitro grade; in-vivo grade	Detail
pGMoligo101086769	Pre-made Cat/Feline APOE siRNA oligo Duplex	101086769	Cat/Feline	In-vitro grade; in-vivo grade	Detail
pGMoligo476438	Pre-made Dog/Canine APOE/Apo-E siRNA oligo Duplex	476438	Dog/Canine	In-vitro grade; in-vivo grade	Detail
pGMoligo281004	Pre-made Bovines/Cattle APOE siRNA oligo Duplex	281004	Bovines/Cattle	In-vitro grade; in-vivo grade	Detail
pGMoligo100065481	Pre-made Equine/Horse APOE siRNA oligo Duplex	100065481	Equine/Horse	In-vitro grade; in-vivo grade	Detail

APOE antibody/GMab

Cat No.	Species	Antibody Name	Format	Classified by tag	Detail
GM-Tg-hg-T21689-Ab	Human	Anti-Human APOE monoclonal antibody	mab	FACS/Biofunctional Antibody, Therapeutics Target antibody, Diagnostic target antibody	Detail
GM-Tg-rg-T21689-Ab	Rat	Anti-Rat APOE monoclonal antibody	mab	FACS/Biofunctional Antibody, Therapeutics Target antibody, Diagnostic target antibody	Detail
GM-Tg-mg-T21689-Ab	Mouse	Anti-Mouse APOE monoclonal antibody	mab	FACS/Biofunctional Antibody, Therapeutics Target antibody, Diagnostic target antibody	Detail
GM-Tg-cynog-T21689-Ab	Cynomolgus/Rhesus macaque	Anti-Cynomolgus/Rhesus macaque APOE monoclonal antibody	mab	FACS/Biofunctional Antibody, Therapeutics Target antibody, Diagnostic target antibody	Detail
GM-Tg-felg-T21689-Ab	Cat/Feline	Anti-Cat/Feline APOE monoclonal antibody	mab	FACS/Biofunctional Antibody, Therapeutics Target antibody, Diagnostic target antibody	Detail
GM-Tg-cang-T21689-Ab	Dog/Canine	Anti-Dog/Canine APOE monoclonal antibody	mab	FACS/Biofunctional Antibody, Therapeutics Target antibody, Diagnostic target antibody	Detail
GM-Tg-bovg-T21689-Ab	Bovines/Cattle	Anti-Bovines/Cattle APOE monoclonal antibody	mab	FACS/Biofunctional Antibody, Therapeutics Target antibody, Diagnostic target antibody	Detail
GM-Tg-equg-T21689-Ab	Equine/Horse	Anti-Equine/Horse APOE monoclonal antibody	mab	FACS/Biofunctional Antibody, Therapeutics Target antibody, Diagnostic target antibody	Detail

APOE VLP (virus-like particle)/protein

Cat No.	Species	Antigen Name	Expression Platform	Detail
GM-Tg-hg-T21689-Ag	Human	Human APOE VLP (virus-like particle)	HEK293	Products Developing
GM-Tg-rg-T21689-Ag	Rat	Rat APOE VLP (virus-like particle)	HEK293	Products Developing
GM-Tg-mg-T21689-Ag	Mouse	Mouse APOE VLP (virus-like particle)	HEK293	Products Developing
GM-Tg-cynog-T21689-Ag	Cynomolgus/Rhesus macaque	Cynomolgus/Rhesus macaque APOE VLP (virus-like particle)	HEK293	Products Developing
GM-Tg-felg-T21689-Ag	Cat/Feline	Cat/Feline APOE VLP (virus-like particle)	HEK293	Products Developing
GM-Tg-cang-T21689-Ag	Dog/Canine	Dog/Canine APOE VLP (virus-like particle)	HEK293	Products Developing
GM-Tg-bovg-T21689-Ag	Bovines/Cattle	Bovines/Cattle APOE VLP (virus-like particle)	HEK293	Products Developing
GM-Tg-equg-T21689-Ag	Equine/Horse	Equine/Horse APOE VLP (virus-like particle)	HEK293	Products Developing