Human APOE/AD2/APO-E ORF/cDNA clone-Mammalian (Non-Viral Vector) plasmid (NM_000041.4)

Cat. No.: pGMPC004755
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human APOE/AD2/APO-E Non-Viral expression plasmid (overexpression vector) for mouse APOE overexpression in unique cell transient transfection and stable cell line development.


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Product Description

Catalog ID pGMPC004755
Gene Name APOE
Accession Number NM_000041.4
Gene ID 348
Species Human
Product Type Mammalian (Non-Viral Vector) plasmid (overexpression)
Insert Length 954 bp
Gene Alias AD2,APO-E,ApoE4,LDLCQ5,LPG
Fluorescent Reporter Null
Mammalian Cell Selection Null
Fusion Tag HA (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGAAGGTTCTGTGGGCTGCGTTGCTGGTCACATTCCTGGCAGGATGCCAGGCCAAGGTGGAGCAAGCGGTGGAGACAGAGCCGGAGCCCGAGCTGCGCCAGCAGACCGAGTGGCAGAGCGGCCAGCGCTGGGAACTGGCACTGGGTCGCTTTTGGGATTACCTGCGCTGGGTGCAGACACTGTCTGAGCAGGTGCAGGAGGAGCTGCTCAGCTCCCAGGTCACCCAGGAACTGAGGGCGCTGATGGACGAGACCATGAAGGAGTTGAAGGCCTACAAATCGGAACTGGAGGAACAACTGACCCCGGTGGCGGAGGAGACGCGGGCACGGCTGTCCAAGGAGCTGCAGGCGGCGCAGGCCCGGCTGGGCGCGGACATGGAGGACGTGTGCGGCCGCCTGGTGCAGTACCGCGGCGAGGTGCAGGCCATGCTCGGCCAGAGCACCGAGGAGCTGCGGGTGCGCCTCGCCTCCCACCTGCGCAAGCTGCGTAAGCGGCTCCTCCGCGATGCCGATGACCTGCAGAAGCGCCTGGCAGTGTACCAGGCCGGGGCCCGCGAGGGCGCCGAGCGCGGCCTCAGCGCCATCCGCGAGCGCCTGGGGCCCCTGGTGGAACAGGGCCGCGTGCGGGCCGCCACTGTGGGCTCCCTGGCCGGCCAGCCGCTACAGGAGCGGGCCCAGGCCTGGGGCGAGCGGCTGCGCGCGCGGATGGAGGAGATGGGCAGCCGGACCCGCGACCGCCTGGACGAGGTGAAGGAGCAGGTGGCGGAGGTGCGCGCCAAGCTGGAGGAGCAGGCCCAGCAGATACGCCTGCAGGCCGAGGCCTTCCAGGCCCGCCTCAAGAGCTGGTTCGAGCCCCTGGTGGAAGACATGCAGCGCCAGTGGGCCGGGCTGGTGGAGAAGGTGCAGGCTGCCGTGGGCACCAGCGCCGCCCCTGTGCCCAGCGACAATCACTGA
ORF Protein Sequence MKVLWAALLVTFLAGCQAKVEQAVETEPEPELRQQTEWQSGQRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQLTPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRVRLASHLRKLRKRLLRDADDLQKRLAVYQAGAREGAERGLSAIRERLGPLVEQGRVRAATVGSLAGQPLQERAQAWGERLRARMEEMGSRTRDRLDEVKEQVAEVRAKLEEQAQQIRLQAEAFQARLKSWFEPLVEDMQRQWAGLVEKVQAAVGTSAAPVPSDNH

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T21689-Ab Anti-APOE/ AD2/ APO-E monoclonal antibody
    Target Antigen GM-Tg-g-T21689-Ag APOE VLP (virus-like particle)
    ORF Viral Vector pGMLP001912 Human APOE Lentivirus plasmid
    ORF Viral Vector pGMLV001748 Human APOE Lentivirus plasmid
    ORF Viral Vector pGMAAV000334 Human APOE Adeno-associate virus(AAV) plasmid
    ORF Viral Vector pGMAAV001436 Human APOE Adeno-associate virus(AAV) plasmid
    ORF Viral Vector pGMPC004755 Human APOE Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector vGMLP001912 Human APOE Lentivirus particle
    ORF Viral Vector vGMLV001748 Human APOE Lentivirus particle
    ORF Viral Vector vGMAAV000334 Human APOE Adeno-associate virus(AAV) particle
    ORF Viral Vector vGMAAV001436 Human APOE Adeno-associate virus(AAV) particle


    Target information

    Target ID GM-T21689
    Target Name APOE
    Gene Group Identifier
    (Target Gene ID in Homo species)
    348
    Gene ID 100065481 (Equus caballus), 101086769 (Felis catus), 11816 (Mus musculus), 25728 (Rattus norvegicus)
    281004 (Bos taurus), 348 (Homo sapiens), 476438 (Canis lupus familiaris), 714623 (Macaca mulatta)
    Gene Symbols & Synonyms APOE,Apoe,Apo-E,APOEA,AD2,LPG,APO-E,ApoE4,LDLCQ5
    Target Alternative Names AD2,APO-E,APOE,APOEA,Apo-E,ApoE4,Apoe,Apolipoprotein E,LDLCQ5,LPG
    Uniprot Accession P02649,P02650,P08226,P18649,Q03247,Q28502
    Additional SwissProt Accessions: P08226,P02650,Q03247,P02649,P18649,Q28502
    Uniprot Entry Name
    Protein Sub-location Transmembrane Protein
    Category Therapeutics Target, Diagnostics Biomarker
    Disease cancer, Type 1 diabetes mellitus, Alzheimer's Disease, Breast neoplasms, Dent disease, Malignant neoplasm of bladder, Other diseases of intestines (K55-K64)
    Disease from KEGG Cholesterol metabolism, Alzheimer disease
    Gene Ensembl ENSECAG00000008236, ENSMUSG00000002985, ENSBTAG00000010123, ENSG00000130203, ENSCAFG00845006705, ENSMMUG00000014305
    Target Classification


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