Explore MGEA5/OGA gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Introcelluar Protein.
The dynamic modification of cytoplasmic and nuclear proteins by O-linked N-acetylglucosamine (O-GlcNAc) addition and removal on serine and threonine residues is catalyzed by OGT (MIM 300255), which adds O-GlcNAc, and MGEA5, a glycosidase that removes O-GlcNAc modifications (Gao et al., 2001 [PubMed 11148210]).[supplied by OMIM, Mar 2008]
| Target ID |
GM-T19567
|
| Target Name |
MGEA5/OGA
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
10724
|
| Gene ID |
100060245 (Equus caballus), 101098493 (Felis catus), 10724 (Homo sapiens), 154968 (Rattus norvegicus)
477802 (Canis lupus familiaris), 538561 (Bos taurus), 712370 (Macaca mulatta), 76055 (Mus musculus)
|
| Target Alternative Names |
Beta-N-acetylglucosaminidase,Beta-N-acetylhexosaminidase,Beta-hexosaminidase,Hy5,MEA5,MGEA5,Meningioma-expressed antigen 5,Mgea5,N-acetyl-beta-D-glucosaminidase,N-acetyl-beta-glucosaminidase,NCOAT,Ncoat,Nuclear cytoplasmic O-GlcNAcase and acetyltransferase (NCOAT),OGA,Oga,Protein O-GlcNAcase
|
| Uniprot Accession |
O60502,Q8VIJ5,Q9EQQ9
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer, Acute kidney failure, Chronic tubulo-interstitial nephritis, Diabetic Nephropathy, Intraoperative Renal Injury, Nephropathy induced by heavy metals, Nephropathy induced by other drugs, medicaments and biological substances, Proteinuria, Sickle Cell Nephropathy, Type 1 diabetes mellitus with diabetic nephropathy, Type 2 diabetes mellitus
|
| Disease from KEGG |
Insulin resistance
|
| Gene Ensembl |
ENSECAG00000018731, ENSG00000198408, ENSBTAG00000016336, ENSMMUG00000015775, ENSMUSG00000025220
|
Pre-made viral vector of MGEA5/OGA cDNA Clones/ORF Plasmid
MGEA5/OGA siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo10724 | Pre-made Human OGA/MEA5/MGEA5 siRNA oligo Duplex | 10724 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo154968 | Pre-made Rat Oga/Mgea5/Ncoat siRNA oligo Duplex | 154968 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo76055 | Pre-made Mouse Oga/Hy5/Mgea5 siRNA oligo Duplex | 76055 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo712370 | Pre-made Cynomolgus/Rhesus macaque OGA/MGEA5 siRNA oligo Duplex | 712370 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101098493 | Pre-made Cat/Feline OGA/MGEA5 siRNA oligo Duplex | 101098493 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo477802 | Pre-made Dog/Canine OGA/MGEA5 siRNA oligo Duplex | 477802 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo538561 | Pre-made Bovines/Cattle OGA/MGEA5 siRNA oligo Duplex | 538561 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100060245 | Pre-made Equine/Horse OGA/MGEA5 siRNA oligo Duplex | 100060245 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
MGEA5/OGA antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T19567-Ab | Human | Anti-Human MGEA5/OGA monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T19567-Ab | Rat | Anti-Rat MGEA5/OGA monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T19567-Ab | Mouse | Anti-Mouse MGEA5/OGA monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T19567-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque MGEA5/OGA monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T19567-Ab | Cat/Feline | Anti-Cat/Feline MGEA5/OGA monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T19567-Ab | Dog/Canine | Anti-Dog/Canine MGEA5/OGA monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T19567-Ab | Bovines/Cattle | Anti-Bovines/Cattle MGEA5/OGA monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T19567-Ab | Equine/Horse | Anti-Equine/Horse MGEA5/OGA monoclonal antibody | mab | Therapeutics Target antibody | Detail |
MGEA5/OGA recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T19567-Ag | Human | Human MGEA5/OGA recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T19567-Ag | Rat | Rat MGEA5/OGA recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T19567-Ag | Mouse | Mouse MGEA5/OGA recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T19567-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque MGEA5/OGA recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T19567-Ag | Cat/Feline | Cat/Feline MGEA5/OGA recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T19567-Ag | Dog/Canine | Dog/Canine MGEA5/OGA recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T19567-Ag | Bovines/Cattle | Bovines/Cattle MGEA5/OGA recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T19567-Ag | Equine/Horse | Equine/Horse MGEA5/OGA recombinant protein | Mammalian cell | Detail |
