Human OGA/MEA5/MGEA5 ORF/cDNA clone-Mammalian (Non-Viral Vector) plasmid (NM_012215)

Cat. No.: pGMPC001034
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human OGA/MEA5/MGEA5 Non-Viral expression plasmid (overexpression vector) for mouse OGA overexpression in unique cell transient transfection and stable cell line development.

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Product Description

Catalog ID pGMPC001034
Gene Name OGA
Accession Number NM_012215
Gene ID 10724
Species Human
Product Type Mammalian (Non-Viral Vector) plasmid (overexpression)
Insert Length 2751 bp
Gene Alias MEA5,MGEA5,NCOAT
Fluorescent Reporter EGFP
Mammalian Cell Selection Null
Fusion Tag 3xflag (C-Terminal)
Promoter EF1
Resistance Amplicin
ORF Nucleotide Sequence ATGGTGCAGAAGGAGAGTCAAGCGACGTTGGAGGAGCGGGAGAGCGAGCTCAGCTCCAACCCTGCCGCCTCTGCGGGGGCATCGCTGGAGCCGCCGGCAGCTCCGGCACCCGGAGAAGACAACCCCGCCGGGGCTGGGGGAGCGGCGGTGGCCGGGGCTGCAGGAGGGGCTCGGCGGTTCCTCTGCGGTGTGGTGGAAGGATTTTATGGAAGACCTTGGGTTATGGAACAGAGAAAAGAACTCTTTAGAAGGCTCCAGAAATGGGAATTAAATACATACTTGTATGCCCCAAAAGATGACTACAAACATAGGATGTTTTGGCGAGAGATGTATTCAGTGGAGGAAGCTGAGCAACTTATGACTCTCATCTCTGCTGCACGAGAATATGAGATAGAGTTCATCTATGCGATCTCACCTGGATTGGATATCACTTTTTCTAACCCCAAGGAAGTATCCACATTGAAACGTAAATTGGACCAGGTTTCTCAGTTTGGGTGCAGATCATTTGCTTTGCTTTTTGATGATATAGACCATAATATGTGTGCAGCAGACAAAGAGGTATTCAGTTCTTTTGCTCATGCCCAAGTCTCCATCACAAATGAAATCTATCAGTACCTAGGAGAGCCAGAAACTTTCCTCTTCTGTCCCACAGAATACTGTGGCACTTTCTGTTATCCAAATGTGTCTCAGTCTCCATATTTAAGGACTGTGGGTGAAAAGCTTCTACCTGGAATTGAAGTGCTTTGGACAGGTCCCAAAGTTGTTTCTAAAGAAATTCCAGTAGAGTCCATCGAAGAGGTTTCTAAGATTATTAAGAGAGCTCCAGTAATCTGGGATAACATTCATGCTAATGATTATGATCAGAAGAGACTGTTTCTGGGCCCGTACAAAGGAAGATCCACAGAACTCATCCCACGGTTAAAAGGAGTCCTCACTAATCCAAATTGTGAATTTGAAGCCAACTACGTTGCTATCCACACCCTTGCCACCTGGTACAAATCAAACATGAATGGAGTGAGAAAAGATGTAGTGATGACTGACAGTGAAGATAGTACTGTGTCCATCCAGATAAAATTAGAAAATGAAGGCAGTGATGAAGATATTGAAACTGATGTACTCTATAGTCCACAGATGGCTCTAAAGCTAGCATTAACAGAATGGTTGCAAGAGTTTGGTGTGCCTCATCAATACAGCAGTAGGCAAGTTGCACACAGTGGAGCTAAAGCAAGTGTAGTTGATGGGACTCCTTTAGTTGCAGCACCCTCTTTAAATGCCACAACCGTAGTAACAACAGTTTATCAGGAGCCCATTATGAGCCAGGGAGCAGCCTTGAGTGGTGAGCCTACTACTCTGACCAAGGAAGAAGAAAAGAAACAGCCTGATGAAGAACCCATGGACATGGTGGTGGAAAAACAAGAAGAAACGGACCACAAGAATGACAATCAAATACTGAGTGAAATTGTTGAAGCGAAAATGGCAGAGGAATTGAAACCAATGGACACTGATAAAGAGAGCATAGCTGAATCAAAATCCCCAGAGATGTCCATGCAAGAAGATTGTATTAGTGACATTGCCCCCATGCAAACTGATGAACAGACAAACAAGGAGCAGTTTGTGCCAGGTCCAAATGAAAAGCCTTTGTACACTGCGGAACCAGTGACCCTGGAGGATTTGCAGTTACTTGCTGATCTATTCTACCTTCCTTACGAGCATGGACCCAAAGGAGCACAGATGTTACGGGAATTTCAATGGCTTCGAGCAAATAGTAGTGTTGTCAGTGTCAATTGCAAAGGAAAAGACTCTGAAAAAATTGAAGAATGGCGGTCACGAGCAGCCAAGTTTGAAGAGATGTGTGGACTAGTGATGGGAATGTTCACTCGGCTCTCCAATTGTGCCAACAGGACAATTCTTTATGACATGTACTCCTATGTTTGGGATATCAAGAGTATAATGTCTATGGTGAAGTCTTTTGTACAGTGGTTAGGGTGTCGTAGTCATTCTTCAGCACAATTCTTAATTGGAGACCAAGAACCCTGGGCCTTTAGAGGTGGTCTAGCAGGAGAGTTCCAGCGTTTGCTGCCAATTGATGGGGCAAATGATCTCTTTTTTCAGCCACCTCCACTGACTCCTACCTCCAAAGTTTATACTATCAGACCTTATTTTCCTAAGGATGAGGCATCCGTGTACAAGATTTGCAGAGAAATGTATGACGATGGAGTGGGTTTACCCTTTCAAAGTCAGCCTGATCTTATTGGAGACAAGTTAGTAGGAGGGCTGCTTTCCCTCAGCCTGGATTACTGCTTTGTCCTAGAAGATGAAGATGGCATATGTGGTTATGCCTTGGGCACTGTAGATGTGACCCCCTTTATTAAAAAATGTAAAATTTCCTGGATCCCCTTCATGCAGGAGAAGTATACCAAGCCAAATGGTGACAAGGAACTCTCTGAGGCTGAGAAAATAATGTTGAGTTTCCATGAAGAACAGGAAGTACTGCCAGAAACTTTCCTTGCTAATTTCCCTTCTCTGATAAAGATGGACATTCACAAAAAAGTAACTGACCCAAGTGTGGCCAAAAGCATGATGGCTTGCCTCCTGTCTTCACTGAAGGCTAATGGCTCCCGGGGAGCTTTCTGTGAAGTGAGACCAGATGATAAAAGAATTCTGGAATTTTACAGCAAGTTAGGATGTTTTGAAATTGCAAAAATGGAAGGATTTCCAAAGGATGTGGTTATACTTGGTCGGAGCCTGTGA
ORF Protein Sequence MVQKESQATLEERESELSSNPAASAGASLEPPAAPAPGEDNPAGAGGAAVAGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKASVVDGTPLVAAPSLNATTVVTTVYQEPIMSQGAALSGEPTTLTKEEEKKQPDEEPMDMVVEKQEETDHKNDNQILSEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCISDIAPMQTDEQTNKEQFVPGPNEKPLYTAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKDSEKIEEWRSRAAKFEEMCGLVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYALGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFPSLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T19567-Ab Anti-OGA monoclonal antibody
    Target Antigen GM-Tg-g-T19567-Ag OGA protein
    ORF Viral Vector pGMAD000486 Human OGA Adenovirus plasmid
    ORF Viral Vector pGMAD001646 Human OGA Adenovirus plasmid
    ORF Viral Vector pGMPC001034 Human OGA Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector vGMAD000486 Human OGA Adenovirus particle
    ORF Viral Vector vGMAD001646 Human OGA Adenovirus particle


    Target information

    Target ID GM-T19567
    Target Name MGEA5/OGA
    Gene Group Identifier
    （Target Gene ID in Homo species)         		10724
    Gene ID 100060245 (Equus caballus), 101098493 (Felis catus), 10724 (Homo sapiens), 154968 (Rattus norvegicus)
    477802 (Canis lupus familiaris), 538561 (Bos taurus), 712370 (Macaca mulatta), 76055 (Mus musculus)
    Gene Symbols & Synonyms OGA,Oga,MGEA5,MEA5,NCOAT,Mgea5,Ncoat,Hy5
    Target Alternative Names Beta-N-acetylglucosaminidase,Beta-N-acetylhexosaminidase,Beta-hexosaminidase,Hy5,MEA5,MGEA5,Meningioma-expressed antigen 5,Mgea5,N-acetyl-beta-D-glucosaminidase,N-acetyl-beta-glucosaminidase,NCOAT,Ncoat,Nuclear cytoplasmic O-GlcNAcase and acetyltransferase (NCOAT),OGA,Oga,Protein O-GlcNAcase
    Uniprot Accession O60502,Q8VIJ5,Q9EQQ9
    Additional SwissProt Accessions: O60502,Q8VIJ5,Q9EQQ9
    Uniprot Entry Name
    Protein Sub-location Introcelluar Protein
    Category Therapeutics Target
    Disease cancer, Acute kidney failure, Chronic tubulo-interstitial nephritis, Diabetic Nephropathy, Intraoperative Renal Injury, Nephropathy induced by heavy metals, Nephropathy induced by other drugs, medicaments and biological substances, Proteinuria, Sickle Cell Nephropathy, Type 1 diabetes mellitus with diabetic nephropathy, Type 2 diabetes mellitus
    Disease from KEGG Insulin resistance
    Gene Ensembl ENSECAG00000018731, ENSG00000198408, ENSBTAG00000016336, ENSMMUG00000015775, ENSMUSG00000025220
    Target Classification


    About GMVC

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