Recombinant multi-species MGEA5/OGA protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MGEA5/OGA protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The dynamic modification of cytoplasmic and nuclear proteins by O-linked N-acetylglucosamine (O-GlcNAc) addition and removal on serine and threonine residues is catalyzed by OGT (MIM 300255), which adds O-GlcNAc, and MGEA5, a glycosidase that removes O-GlcNAc modifications (Gao et al., 2001 [PubMed 11148210]).[supplied by OMIM, Mar 2008]
The Alternative Names of target: Beta-N-acetylglucosaminidase,Beta-N-acetylhexosaminidase,Beta-hexosaminidase,Hy5,MEA5,MGEA5,Meningioma-expressed antigen 5,Mgea5,N-acetyl-beta-D-glucosaminidase,N-acetyl-beta-glucosaminidase,NCOAT,Ncoat,Nuclear cytoplasmic O-GlcNAcase and acetyltransferase (NCOAT),OGA,Oga,Protein O-GlcNAcase

Target products collectionGo to MGEA5/OGA products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T19567-Ag-1/ GM-Tg-hg-T19567-Ag-2 Human MGEA5/OGA protein Human
GM-Tg-rg-T19567-Ag-1/ GM-Tg-rg-T19567-Ag-2 Rat MGEA5/OGA protein Rat
GM-Tg-mg-T19567-Ag-1/ GM-Tg-mg-T19567-Ag-2 Mouse MGEA5/OGA protein Mouse
GM-Tg-cynog-T19567-Ag-1/ GM-Tg-cynog-T19567-Ag-2 Cynomolgus/Rhesus macaque MGEA5/OGA protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T19567-Ag-1/ GM-Tg-felg-T19567-Ag-2 Feline MGEA5/OGA protein Feline
GM-Tg-cang-T19567-Ag-1/ GM-Tg-cang-T19567-Ag-2 Canine MGEA5/OGA protein Canine
GM-Tg-bovg-T19567-Ag-1/ GM-Tg-bovg-T19567-Ag-2 Bovine MGEA5/OGA protein Bovine
GM-Tg-equg-T19567-Ag-1/ GM-Tg-equg-T19567-Ag-2 Equine MGEA5/OGA protein Equine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T19567-Ag-1/ GM-Tg-hg-T19567-Ag-2; GM-Tg-rg-T19567-Ag-1/ GM-Tg-rg-T19567-Ag-2;
GM-Tg-mg-T19567-Ag-1/ GM-Tg-mg-T19567-Ag-2; GM-Tg-cynog-T19567-Ag-1/ GM-Tg-cynog-T19567-Ag-2;
GM-Tg-felg-T19567-Ag-1/ GM-Tg-felg-T19567-Ag-2; GM-Tg-cang-T19567-Ag-1/ GM-Tg-cang-T19567-Ag-2;
GM-Tg-bovg-T19567-Ag-1/ GM-Tg-bovg-T19567-Ag-2; GM-Tg-equg-T19567-Ag-1/ GM-Tg-equg-T19567-Ag-2
Products Name MGEA5/OGA protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name MGEA5/OGA
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MGEA5/OGA protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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