Explore IL-1 alpha/IL1A gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T16340
|
| Target Name |
IL-1 alpha/IL1A
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
3552
|
| Gene ID |
100064969 (Equus caballus), 16175 (Mus musculus), 24493 (Rattus norvegicus), 281250 (Bos taurus)
3552 (Homo sapiens), 403782 (Canis lupus familiaris), 493944 (Felis catus), 700193 (Macaca mulatta)
|
| Target Alternative Names |
Hematopoietin-1,IL-1 alpha,IL-1A,IL-1F1,IL1,IL1-ALPHA,IL1A,IL1F1,Il-1a,Il1a,Interleukin-1 alpha,L1A
|
| Uniprot Accession |
Q28385,P01582,P16598,P08831,P01583,O46612,O46613,P48089
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, INN Index, Cytokine Target
|
| Disease |
cancer, Sarcoidosis, ovarian cancer, Urinary bladder urothelial carcinoma
|
| Disease from KEGG |
MAPK signaling pathway, Cytokine-cytokine receptor interaction, Cellular senescence, Osteoclast differentiation, Hematopoietic cell lineage, AGE-RAGE signaling pathway in diabetic complications, Type I diabetes mellitus, Alzheimer disease, Pertussis, Leishmaniasis, Tuberculosis, Measles, Influenza A, Inflammatory bowel disease, Rheumatoid arthritis, Graft-versus-host disease, Fluid shear stress and atherosclerosis
|
| Gene Ensembl |
ENSECAG00000023727, ENSMUSG00000027399, ENSG00000115008, ENSCAFG00845011308, ENSMMUG00000052787
|
Pre-made viral vector of IL-1 alpha/IL1A cDNA Clones/ORF Plasmid
IL-1 alpha/IL1A siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3552 | Pre-made Human IL1A/IL1/IL-1A siRNA oligo Duplex | 3552 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo24493 | Pre-made Rat Il1a/IL-1F1/IL-1 alpha siRNA oligo Duplex | 24493 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo16175 | Pre-made Mouse Il1a/Il-1a siRNA oligo Duplex | 16175 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo700193 | Pre-made Cynomolgus/Rhesus macaque IL1A siRNA oligo Duplex | 700193 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo493944 | Pre-made Cat/Feline IL1A/L1A siRNA oligo Duplex | 493944 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo403782 | Pre-made Dog/Canine IL1A siRNA oligo Duplex | 403782 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281250 | Pre-made Bovines/Cattle IL1A siRNA oligo Duplex | 281250 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100064969 | Pre-made Equine/Horse IL1A siRNA oligo Duplex | 100064969 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
IL-1 alpha/IL1A antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T16340-Ab | Human | Anti-Human IL-1 alpha/IL1A monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-rg-T16340-Ab | Rat | Anti-Rat IL-1 alpha/IL1A monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-mg-T16340-Ab | Mouse | Anti-Mouse IL-1 alpha/IL1A monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-T16340-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque IL-1 alpha/IL1A monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-felg-T16340-Ab | Cat/Feline | Anti-Cat/Feline IL-1 alpha/IL1A monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cang-T16340-Ab | Dog/Canine | Anti-Dog/Canine IL-1 alpha/IL1A monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-T16340-Ab | Bovines/Cattle | Anti-Bovines/Cattle IL-1 alpha/IL1A monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-equg-T16340-Ab | Equine/Horse | Anti-Equine/Horse IL-1 alpha/IL1A monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
IL-1 alpha/IL1A VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T16340-Ag | Human | Human IL-1 alpha/IL1A VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T16340-Ag | Rat | Rat IL-1 alpha/IL1A VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T16340-Ag | Mouse | Mouse IL-1 alpha/IL1A VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T16340-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque IL-1 alpha/IL1A VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T16340-Ag | Cat/Feline | Cat/Feline IL-1 alpha/IL1A VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T16340-Ag | Dog/Canine | Dog/Canine IL-1 alpha/IL1A VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T16340-Ag | Bovines/Cattle | Bovines/Cattle IL-1 alpha/IL1A VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T16340-Ag | Equine/Horse | Equine/Horse IL-1 alpha/IL1A VLP (virus-like particle) | HEK293 | Products Developing |
