Explore KCNK3/TASK1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
This gene encodes a member of the superfamily of potassium channel proteins that contain two pore-forming P domains. The encoded protein is an outwardly rectifying channel that is sensitive to changes in extracellular pH and is inhibited by extracellular acidification. Also referred to as an acid-sensitive potassium channel, it is activated by the anesthetics halothane and isoflurane. Although three transcripts are detected in northern blots, there is currently no sequence available to confirm transcript variants for this gene. [provided by RefSeq, Aug 2008]
| Target ID |
GM-T15795
|
| Target Name |
KCNK3/TASK1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
3777
|
| Gene ID |
101082745 (Felis catus), 102150125 (Equus caballus), 16527 (Mus musculus), 29553 (Rattus norvegicus)
3777 (Homo sapiens), 483002 (Canis lupus familiaris), 519188 (Bos taurus), 699287 (Macaca mulatta)
|
| Target Alternative Names |
Acid-sensitive potassium channel protein TASK-1,K2p3.1,KCNK3,Kcnk3,OAT1,PPH4,Potassium channel subfamily K member 3,TASK,TASK-1,TASK1,TBAK1,TWIK-related acid-sensitive K(+) channel 1,Task-1,Two pore potassium channel KT3.1 (Two pore K(+) channel KT3.1),cTBAK-1,rTASK
|
| Uniprot Accession |
O35111,O54912,O14649
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome
|
| Gene Ensembl |
ENSECAG00000038775, ENSMUSG00000049265, ENSG00000171303, ENSCAFG00845028885, ENSBTAG00000051102, ENSMMUG00000056208
|
Pre-made viral vector of KCNK3/TASK1 cDNA Clones/ORF Plasmid
KCNK3/TASK1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3777 | Pre-made Human KCNK3/OAT1/PPH4 siRNA oligo Duplex | 3777 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo29553 | Pre-made Rat Kcnk3/rTASK/Task-1 siRNA oligo Duplex | 29553 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo16527 | Pre-made Mouse Kcnk3/TASK/Task-1 siRNA oligo Duplex | 16527 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo699287 | Pre-made Cynomolgus/Rhesus macaque KCNK3 siRNA oligo Duplex | 699287 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101082745 | Pre-made Cat/Feline KCNK3 siRNA oligo Duplex | 101082745 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo483002 | Pre-made Dog/Canine KCNK3/TASK1 siRNA oligo Duplex | 483002 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo519188 | Pre-made Bovines/Cattle KCNK3 siRNA oligo Duplex | 519188 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo102150125 | Pre-made Equine/Horse KCNK3 siRNA oligo Duplex | 102150125 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
KCNK3/TASK1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T15795-Ab | Human | Anti-Human KCNK3/TASK1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T15795-Ab | Rat | Anti-Rat KCNK3/TASK1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T15795-Ab | Mouse | Anti-Mouse KCNK3/TASK1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T15795-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque KCNK3/TASK1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T15795-Ab | Cat/Feline | Anti-Cat/Feline KCNK3/TASK1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T15795-Ab | Dog/Canine | Anti-Dog/Canine KCNK3/TASK1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T15795-Ab | Bovines/Cattle | Anti-Bovines/Cattle KCNK3/TASK1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T15795-Ab | Equine/Horse | Anti-Equine/Horse KCNK3/TASK1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
KCNK3/TASK1 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T15795-Ag | Human | Human KCNK3/TASK1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T15795-Ag | Rat | Rat KCNK3/TASK1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T15795-Ag | Mouse | Mouse KCNK3/TASK1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T15795-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque KCNK3/TASK1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T15795-Ag | Cat/Feline | Cat/Feline KCNK3/TASK1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T15795-Ag | Dog/Canine | Dog/Canine KCNK3/TASK1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T15795-Ag | Bovines/Cattle | Bovines/Cattle KCNK3/TASK1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T15795-Ag | Equine/Horse | Equine/Horse KCNK3/TASK1 VLP (virus-like particle) | HEK293 | Products Developing |
