P53/TP53 Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore P53/TP53 gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Introcelluar Protein.
This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016]

Target ID	GM-T15739
Target Name	P53/TP53
Gene Group ldentifer （Target Gene ID in Homo species)	7157
Gene ID	100062044 (Equus caballus), 22059 (Mus musculus), 24842 (Rattus norvegicus), 281542 (Bos taurus) 403869 (Canis lupus familiaris), 493847 (Felis catus), 7157 (Homo sapiens), 716170 (Macaca mulatta)
Target Alternative Names	Antigen NY-CO-13,BCC7,BMFS5,Cellular tumor antigen p53,LFS1,P53,Phosphoprotein p53,TP53,TRP53,Tp53,Trp53,Tumor suppressor p53,bbl,bfy,bhy,p44,p53
Uniprot Accession	P79892,P02340,P10361,P67939,Q29537,P41685,P04637,P56424
Protein Sub-location	Introcelluar Protein
Disease	cancer, Lung Cancer, lung cancers, Lung Cancer, Lung, Colon cancer, Bone metastasis, Liver neoplasms, Lung neoplasms
Disease from KEGG	Endocrine resistance, MAPK signaling pathway, Sphingolipid signaling pathway, p53 signaling pathway, PI3K-Akt signaling pathway, Apoptosis, Longevity regulating pathway, Ferroptosis, Cellular senescence, Wnt signaling pathway, Neurotrophin signaling pathway, Thyroid hormone signaling pathway, Hepatitis C, Hepatitis B, Measles, Human cytomegalovirus infection, Human papillomavirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Epstein-Barr virus infection, Pathways in cancer, Proteoglycans in cancer, Colorectal cancer, Pancreatic cancer, Endometrial cancer, Glioma, Prostate cancer, Thyroid cancer, Basal cell carcinoma, Melanoma, Bladder cancer, Chronic myeloid leukemia, Small cell lung cancer, Non-small cell lung cancer, Breast cancer, Hepatocellular carcinoma, Gastric cancer, Central carbon metabolism in cancer, Lipid and atherosclerosis, Fluid shear stress and atherosclerosis
Gene Ensembl	ENSECAG00000008126, ENSMUSG00000059552, ENSBTAG00000001069, ENSCAFG00845024647, ENSG00000141510, ENSMMUG00000008639
Target Classification	Kinase, Pathway, Checkpoint-Immuno Oncology

Pre-made viral vector of P53/TP53 cDNA Clones/ORF Plasmid

Cat No.	Product Name	NMID	GeneID	Species	Type	Marker	Fusion Tag	Promoter	Detail
pGMLP005729	Human TP53/BCC7/BMFS5 Lentivirus plasmid	NM_000546.5	7157	Human	Lentivirus plasmid	ZsGreen	3xflag (C-Terminal)	CMV	Detail
vGMLV001491	Human TP53/BCC7/BMFS5 Lentivirus particle	NM_000546.6	7157	Human	Lentivirus particle	ZsGreen	3xflag (C-Terminal)	CMV	Detail
vGMLP005729	Human TP53/BCC7/BMFS5 Lentivirus particle	NM_000546.5	7157	Human	Lentivirus particle	ZsGreen	3xflag (C-Terminal)	CMV	Detail
pGMPC004811	Human TP53/BCC7/BMFS5 Mammalian (Non-Viral Vector) plasmid	NM_000546.6	7157	Human	Mammalian (Non-Viral Vector) plasmid	EGFP	HA (C-Terminal)	EF1	Detail
pGMPC004757	Human TP53/BCC7/BMFS5 Mammalian (Non-Viral Vector) plasmid	NM_000546.5	7157	Human	Mammalian (Non-Viral Vector) plasmid	ZsGreen	3xflag (C-Terminal)	CMV	Detail
pGMLV001164	Human TP53/BCC7/BMFS5 Lentivirus plasmid	NM_000546.6	7157	Human	Lentivirus plasmid	Null	Null	CMV	Detail
vGMLV002147	Human TP53/BCC7/BMFS5 Lentivirus particle	NM_000546.6	7157	Human	Lentivirus particle	Null	3xflag (C-Terminal)	CMV	Detail
pGMPC000925	Human TP53/BCC7/BMFS5 Mammalian (Non-Viral Vector) plasmid	NM_000546	7157	Human	Mammalian (Non-Viral Vector) plasmid	mCherry	HA (C-Terminal)	CMV	Detail
pGMPC000186	Human TP53 /BCC7/BMFS5 Mammalian (Non-Viral Vector) plasmid	NM_000546.5	7157	Human	Mammalian (Non-Viral Vector) plasmid	EGFP	3xflag (C-Terminal)	EF1	Detail
vGMAD000013	Human TP53/BCC7/LFS1 Adenovirus particle	NM_000546.5	7157	Human	Adenovirus particle	Null	Null	CMV	Detail
pGMAP-SPh-154	Human TP53/LFS1/p53 Adenovirus plasmid	BC003596	7157	Human	Adenovirus plasmid	EGFP	3xflag (C-Terminal)	EF1	Detail
pGMLP-SPh-014	Human TP53/LFS1/p53 Lentivirus plasmid	BC003596	7157	Human	Lentivirus plasmid	ZsGreen	3xflag (C-Terminal)	CMV	Detail
pGMAP000334	Human TP53/LFS1/p53 Adenovirus plasmid	BC003596	7157	Human	Adenovirus plasmid	GFP	3xflag (C-Terminal)	EF1	Detail
vGMAD000926	Human TP53/BCC7/BMFS5 Adenovirus particle	NM_000546.6	7157	Human	Adenovirus particle	EGFP	3xflag (C-Terminal)	EF1	Detail
pGMAAV001555	Human TP53/BCC7/BMFS5 Adeno-associate virus(AAV) plasmid	NM_000546.6	7157	Human	Adeno-associate virus(AAV) plasmid	Null	Null	TERT	Detail
pGMAAV000014	Human TP53/BCC7/LFS1 Adeno-associate virus(AAV) plasmid	NM_001126112.2	7157	Human	Adeno-associate virus(AAV) plasmid	GFP	Null	GFAP	Detail
vGMAAV000014	Human TP53/BCC7/LFS1 Adeno-associate virus(AAV) particle	NM_001126112.2	7157	Human	Adeno-associate virus(AAV) particle	GFP	Null	GFAP	Detail
pGMAD000926	Human TP53/BCC7/BMFS5 Adenovirus plasmid	NM_000546.6	7157	Human	Adenovirus plasmid	EGFP	3xflag (C-Terminal)	EF1	Detail
vGMAAV001555	Human TP53/BCC7/BMFS5 Adeno-associate virus(AAV) particle	NM_000546.6	7157	Human	Adeno-associate virus(AAV) particle	Null	Null	TERT	Detail
vGMAP000334	Human TP53/LFS1/p53 Adenovirus particle	BC003596	7157	Human	Adenovirus particle	GFP	3xflag (C-Terminal)	EF1	Detail
pGMAD000013	Human TP53/BCC7/LFS1 Adenovirus plasmid	NM_000546.5	7157	Human	Adenovirus plasmid	Null	Null	CMV	Detail
pGMLV002147	Human TP53/BCC7/BMFS5 Lentivirus plasmid	NM_000546.6	7157	Human	Lentivirus plasmid	Null	3xflag (C-Terminal)	CMV	Detail
pGMLV001491	Human TP53/BCC7/BMFS5 Lentivirus plasmid	NM_000546.6	7157	Human	Lentivirus plasmid	ZsGreen	3xflag (C-Terminal)	CMV	Detail
vGMLP-SPh-014	Human TP53/LFS1/p53 Lentivirus particle	BC003596	7157	Human	Lentivirus particle	ZsGreen	3xflag (C-Terminal)	CMV	Detail
vGMAP-SPh-154	Human TP53/LFS1/p53 Adenovirus particle	BC003596	7157	Human	Adenovirus particle	EGFP	3xflag (C-Terminal)	EF1	Detail
vGMLV001164	Human TP53/BCC7/BMFS5 Lentivirus particle	NM_000546.6	7157	Human	Lentivirus particle	Null	Null	CMV	Detail
vGMAD001556	Rat Tp53/p53/Trp53 Adenovirus particle	NM_030989.3	24842	Rat	Adenovirus particle	EGFP	3xflag (C-Terminal)	EF1	Detail
vGMAD000347	Rat Tp53/p53/Trp53 Adenovirus particle	NM_030989	24842	Rat	Adenovirus particle	Null	Null	CMV	Detail
pGMPC001097	Rat Tp53/p53/Trp53 Mammalian (Non-Viral Vector) plasmid	NM_030989.3	24842	Rat	Mammalian (Non-Viral Vector) plasmid	EGFP	Null	EF1	Detail
pGMAD001556	Rat Tp53/p53/Trp53 Adenovirus plasmid	NM_030989.3	24842	Rat	Adenovirus plasmid	EGFP	3xflag (C-Terminal)	EF1	Detail
pGMPC000942	Rat Tp53/p53/Trp53 Mammalian (Non-Viral Vector) plasmid	NM_030989.3	24842	Rat	Mammalian (Non-Viral Vector) plasmid	ZsGreen	3xflag (C-Terminal)	CMV	Detail
pGMAD000347	Rat Tp53/p53/Trp53 Adenovirus plasmid	NM_030989	24842	Rat	Adenovirus plasmid	Null	Null	CMV	Detail
pGMAD000539	Mouse Trp53/bbl/bfy Adenovirus plasmid	NM_011640.3	22059	Mouse	Adenovirus plasmid	EGFP	3xflag (C-Terminal)	EF1	Detail
vGMLP-SPm-011	Mouse Trp53/bbl/bfy Lentivirus particle	NM_011640	22059	Mouse	Lentivirus particle	ZsGreen	3xflag (C-Terminal)	CMV	Detail
pGMLV001269	Mouse Trp53/bbl/bfy Lentivirus plasmid	NM_011640	22059	Mouse	Lentivirus plasmid	mCherry	6xHis (C-Terminal)	CMV	Detail
pGMLV001441	Mouse Trp53/bbl/bfy Lentivirus plasmid	NM_011640	22059	Mouse	Lentivirus plasmid	mCherry	6xHis (C-Terminal)	CMV	Detail
vGMAAV001590	Mouse Trp53/bbl/bfy Adeno-associate virus(AAV) particle	NM_011640.3	22059	Mouse	Adeno-associate virus(AAV) particle	Null	Null	SM22a	Detail
vGMLV001441	Mouse Trp53/bbl/bfy Lentivirus particle	NM_011640	22059	Mouse	Lentivirus particle	mCherry	6xHis (C-Terminal)	CMV	Detail
pGMAD001402	Mouse Trp53/bbl/bfy Adenovirus plasmid	NM_011640.3	22059	Mouse	Adenovirus plasmid	Null	Null	CMV	Detail
vGMLV001269	Mouse Trp53/bbl/bfy Lentivirus particle	NM_011640	22059	Mouse	Lentivirus particle	mCherry	6xHis (C-Terminal)	CMV	Detail
vGMAD001402	Mouse Trp53/bbl/bfy Adenovirus particle	NM_011640.3	22059	Mouse	Adenovirus particle	Null	Null	CMV	Detail
pGMAAV001590	Mouse Trp53/bbl/bfy Adeno-associate virus(AAV) plasmid	NM_011640.3	22059	Mouse	Adeno-associate virus(AAV) plasmid	Null	Null	SM22a	Detail
vGMAD000539	Mouse Trp53/bbl/bfy Adenovirus particle	NM_011640.3	22059	Mouse	Adenovirus particle	EGFP	3xflag (C-Terminal)	EF1	Detail
pGMLP-SPm-011	Mouse Trp53/bbl/bfy Lentivirus plasmid	NM_011640	22059	Mouse	Lentivirus plasmid	ZsGreen	3xflag (C-Terminal)	CMV	Detail
pGMAP-SPm-138	Mouse Trp53/bbl/bfy Adenovirus plasmid	NM_011640	22059	Mouse	Adenovirus plasmid	EGFP	3xflag (C-Terminal)	EF1	Detail
vGMAP-SPm-138	Mouse Trp53/bbl/bfy Adenovirus particle	NM_011640	22059	Mouse	Adenovirus particle	EGFP	3xflag (C-Terminal)	EF1	Detail

P53/TP53 siRNA/miRNA/oligo for RNA interfence (RNAi)

Cat No.	Product Name	GeneID	Species	Grade	Detail
pGMoligo7157	Pre-made Human TP53/P53/BCC7 siRNA oligo Duplex	7157	Human	In-vitro grade; in-vivo grade	Detail
pGMoligo24842	Pre-made Rat Tp53/p53/Trp53 siRNA oligo Duplex	24842	Rat	In-vitro grade; in-vivo grade	Detail
pGMoligo22059	Pre-made Mouse Trp53/bbl/bfy siRNA oligo Duplex	22059	Mouse	In-vitro grade; in-vivo grade	Detail
pGMoligo716170	Pre-made Cynomolgus/Rhesus macaque TP53 siRNA oligo Duplex	716170	Cynomolgus/Rhesus macaque	In-vitro grade; in-vivo grade	Detail
pGMoligo493847	Pre-made Cat/Feline TP53/TRP53 siRNA oligo Duplex	493847	Cat/Feline	In-vitro grade; in-vivo grade	Detail
pGMoligo403869	Pre-made Dog/Canine TP53/P53 siRNA oligo Duplex	403869	Dog/Canine	In-vitro grade; in-vivo grade	Detail
pGMoligo281542	Pre-made Bovines/Cattle TP53 siRNA oligo Duplex	281542	Bovines/Cattle	In-vitro grade; in-vivo grade	Detail
pGMoligo100062044	Pre-made Equine/Horse TP53/p53 siRNA oligo Duplex	100062044	Equine/Horse	In-vitro grade; in-vivo grade	Detail

P53/TP53 antibody/GMab

Cat No.	Species	Antibody Name	Format	Detail
GM-Tg-hg-T15739-Ab	Human	Anti-Human P53/TP53 monoclonal antibody	mab	Detail
GM-Tg-rg-T15739-Ab	Rat	Anti-Rat P53/TP53 monoclonal antibody	mab	Detail
GM-Tg-mg-T15739-Ab	Mouse	Anti-Mouse P53/TP53 monoclonal antibody	mab	Detail
GM-Tg-cynog-T15739-Ab	Cynomolgus/Rhesus macaque	Anti-Cynomolgus/Rhesus macaque P53/TP53 monoclonal antibody	mab	Detail
GM-Tg-felg-T15739-Ab	Cat/Feline	Anti-Cat/Feline P53/TP53 monoclonal antibody	mab	Detail
GM-Tg-cang-T15739-Ab	Dog/Canine	Anti-Dog/Canine P53/TP53 monoclonal antibody	mab	Detail
GM-Tg-bovg-T15739-Ab	Bovines/Cattle	Anti-Bovines/Cattle P53/TP53 monoclonal antibody	mab	Detail
GM-Tg-equg-T15739-Ab	Equine/Horse	Anti-Equine/Horse P53/TP53 monoclonal antibody	mab	Detail

P53/TP53 recombinant protein

Cat No.	Species	Antigen Name	Expression Platform	Detail
GM-Tg-hg-T15739-Ag	Human	Human P53/TP53 recombinant protein	Mammalian cell	Detail
GM-Tg-rg-T15739-Ag	Rat	Rat P53/TP53 recombinant protein	Mammalian cell	Detail
GM-Tg-mg-T15739-Ag	Mouse	Mouse P53/TP53 recombinant protein	Mammalian cell	Detail
GM-Tg-cynog-T15739-Ag	Cynomolgus/Rhesus macaque	Cynomolgus/Rhesus macaque P53/TP53 recombinant protein	Mammalian cell	Detail
GM-Tg-felg-T15739-Ag	Cat/Feline	Cat/Feline P53/TP53 recombinant protein	Mammalian cell	Detail
GM-Tg-cang-T15739-Ag	Dog/Canine	Dog/Canine P53/TP53 recombinant protein	Mammalian cell	Detail
GM-Tg-bovg-T15739-Ag	Bovines/Cattle	Bovines/Cattle P53/TP53 recombinant protein	Mammalian cell	Detail
GM-Tg-equg-T15739-Ag	Equine/Horse	Equine/Horse P53/TP53 recombinant protein	Mammalian cell	Detail