Human TP53 /BCC7/BMFS5 ORF/cDNA clone-Mammalian (Non-Viral Vector) plasmid (NM_000546.5)

Cat. No.: pGMPC000186
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human TP53 /BCC7/BMFS5 Non-Viral expression plasmid (overexpression vector) for mouse TP53 overexpression in unique cell transient transfection and stable cell line development.

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Product Description

Catalog ID pGMPC000186
Gene Name TP53
Accession Number NM_000546.5
Gene ID 7157
Species Human
Product Type Mammalian (Non-Viral Vector) plasmid (overexpression)
Insert Length 1182 bp
Gene Alias BCC7,BMFS5,LFS1,P53,TRP53
Fluorescent Reporter EGFP
Mammalian Cell Selection Null
Fusion Tag 3xflag (C-Terminal)
Promoter EF1
Resistance Amplicin
ORF Nucleotide Sequence ATGGAGGAGCCGCAGTCAGATCCTAGCGTCGAGCCCCCTCTGAGTCAGGAAACATTTTCAGACCTATGGAAACTACTTCCTGAAAACAACGTTCTGTCCCCCTTGCCGTCCCAAGCAATGGATGATTTGATGCTGTCCCCGGACGATATTGAACAATGGTTCACTGAAGACCCAGGTCCAGATGAAGCTCCCAGAATGCCAGAGGCTGCTCCCCCCGTGGCCCCTGCACCAGCAGCTCCTACACCGGCGGCCCCTGCACCAGCCCCCTCCTGGCCCCTGTCATCTTCTGTCCCTTCCCAGAAAACCTACCAGGGCAGCTACGGTTTCCGTCTGGGCTTCTTGCATTCTGGGACAGCCAAGTCTGTGACTTGCACGTACTCCCCTGCCCTCAACAAGATGTTTTGCCAACTGGCCAAGACCTGCCCTGTGCAGCTGTGGGTTGATTCCACACCCCCGCCCGGCACCCGCGTCCGCGCCATGGCCATCTACAAGCAGTCACAGCACATGACGGAGGTTGTGAGGCGCTGCCCCCACCATGAGCGCTGCTCAGATAGCGATGGTCTGGCCCCTCCTCAGCATCTTATCCGAGTGGAAGGAAATTTGCGTGTGGAGTATTTGGATGACAGAAACACTTTTCGACATAGTGTGGTGGTGCCCTATGAGCCGCCTGAGGTTGGCTCTGACTGTACCACCATCCACTACAACTACATGTGTAACAGTTCCTGCATGGGCGGCATGAACCGGAGGCCCATCCTCACCATCATCACACTGGAAGACTCCAGTGGTAATCTACTGGGACGGAACAGCTTTGAGGTGCGTGTTTGTGCCTGTCCTGGGAGAGACCGGCGCACAGAGGAAGAGAATCTCCGCAAGAAAGGGGAGCCTCACCACGAGCTGCCCCCAGGGAGCACTAAGCGAGCACTGCCCAACAACACCAGCTCCTCTCCCCAGCCAAAGAAGAAACCACTGGATGGAGAATATTTCACCCTTCAGATCCGTGGGCGTGAGCGCTTCGAGATGTTCCGAGAGCTGAATGAGGCCTTGGAACTCAAGGATGCCCAGGCTGGGAAGGAGCCAGGGGGGAGCAGGGCTCACTCCAGCCACCTGAAGTCCAAAAAGGGTCAGTCTACCTCCCGCCATAAAAAACTCATGTTCAAGACAGAAGGGCCTGACTCAGACTGA
ORF Protein Sequence MEEPQSDPSVEPPLSQETFSDLWKLLPENNVLSPLPSQAMDDLMLSPDDIEQWFTEDPGPDEAPRMPEAAPPVAPAPAAPTPAAPAPAPSWPLSSSVPSQKTYQGSYGFRLGFLHSGTAKSVTCTYSPALNKMFCQLAKTCPVQLWVDSTPPPGTRVRAMAIYKQSQHMTEVVRRCPHHERCSDSDGLAPPQHLIRVEGNLRVEYLDDRNTFRHSVVVPYEPPEVGSDCTTIHYNYMCNSSCMGGMNRRPILTIITLEDSSGNLLGRNSFEVRVCACPGRDRRTEEENLRKKGEPHHELPPGSTKRALPNNTSSSPQPKKKPLDGEYFTLQIRGRERFEMFRELNEALELKDAQAGKEPGGSRAHSSHLKSKKGQSTSRHKKLMFKTEGPDSD

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T69823-Ab Anti-TP53 Y220C monoclonal antibody
    Target Antigen GM-Tg-g-T69823-Ag TP53 Y220C/TP53 protein
    ORF Viral Vector pGMLP005729 Human TP53 Lentivirus plasmid
    ORF Viral Vector pGMLV001164 Human TP53 Lentivirus plasmid
    ORF Viral Vector pGMLV001491 Human TP53 Lentivirus plasmid
    ORF Viral Vector pGMLV002147 Human TP53 Lentivirus plasmid
    ORF Viral Vector pGMAD000013 Human TP53 Adenovirus plasmid
    ORF Viral Vector pGMAD000926 Human TP53 Adenovirus plasmid
    ORF Viral Vector pGMAAV000014 Human TP53 Adeno-associate virus(AAV) plasmid
    ORF Viral Vector pGMAAV001555 Human TP53 Adeno-associate virus(AAV) plasmid
    ORF Viral Vector pGMAP000334 Human TP53 Adenovirus plasmid
    ORF Viral Vector pGMLP-SPh-014 Human TP53 Lentivirus plasmid
    ORF Viral Vector pGMAP-SPh-154 Human TP53 Adenovirus plasmid
    ORF Viral Vector pGMPC000186 Human TP53 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector pGMPC000925 Human TP53 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector pGMPC004757 Human TP53 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector pGMPC004811 Human TP53 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector vGMLP005729 Human TP53 Lentivirus particle
    ORF Viral Vector vGMLV001164 Human TP53 Lentivirus particle
    ORF Viral Vector vGMLV001491 Human TP53 Lentivirus particle
    ORF Viral Vector vGMLV002147 Human TP53 Lentivirus particle
    ORF Viral Vector vGMAD000013 Human TP53 Adenovirus particle
    ORF Viral Vector vGMAD000926 Human TP53 Adenovirus particle
    ORF Viral Vector vGMAAV000014 Human TP53 Adeno-associate virus(AAV) particle
    ORF Viral Vector vGMAAV001555 Human TP53 Adeno-associate virus(AAV) particle
    ORF Viral Vector vGMAP000334 Human TP53 Adenovirus particle
    ORF Viral Vector vGMLP-SPh-014 Human TP53 Lentivirus particle
    ORF Viral Vector vGMAP-SPh-154 Human TP53 Adenovirus particle


    Target information

    Target ID GM-T69823
    Target Name TP53 Y220C
    Gene Group Identifier
    （Target Gene ID in Homo species)         		7157
    Gene ID 100062044 (Equus caballus), 22059 (Mus musculus), 24842 (Rattus norvegicus), 281542 (Bos taurus)
    403869 (Canis lupus familiaris), 493847 (Felis catus), 7157 (Homo sapiens), 716170 (Macaca mulatta)
    Gene Symbols & Synonyms TP53,Trp53,Tp53,p53,bbl,bfy,bhy,p44,P53,TRP53,BCC7,LFS1,BMFS5
    Target Alternative Names Antigen NY-CO-13,BCC7,BMFS5,Cellular tumor antigen p53,LFS1,P53,Phosphoprotein p53,TP53,TP53 Y220C,TRP53,Tp53,Trp53,Tumor suppressor p53,bbl,bfy,bhy,p44,p53
    Uniprot Accession P02340,P04637,P10361,P41685,P56424,P67939,P79892,Q29537
    Additional SwissProt Accessions: P79892,P02340,P10361,P67939,Q29537,P41685,P04637,P56424
    Uniprot Entry Name
    Protein Sub-location Introcelluar Protein
    Category Therapeutics Target, Immuno-oncology Target
    Disease cancer, Lung Cancer, lung cancers, Lung Cancer, Lung, Colon cancer, Bone metastasis, Liver neoplasms, Lung neoplasms
    Disease from KEGG Endocrine resistance, MAPK signaling pathway, Sphingolipid signaling pathway, p53 signaling pathway, PI3K-Akt signaling pathway, Apoptosis, Longevity regulating pathway, Ferroptosis, Cellular senescence, Wnt signaling pathway, Neurotrophin signaling pathway, Thyroid hormone signaling pathway, Hepatitis C, Hepatitis B, Measles, Human cytomegalovirus infection, Human papillomavirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Epstein-Barr virus infection, Pathways in cancer, Proteoglycans in cancer, Colorectal cancer, Pancreatic cancer, Endometrial cancer, Glioma, Prostate cancer, Thyroid cancer, Basal cell carcinoma, Melanoma, Bladder cancer, Chronic myeloid leukemia, Small cell lung cancer, Non-small cell lung cancer, Breast cancer, Hepatocellular carcinoma, Gastric cancer, Central carbon metabolism in cancer, Lipid and atherosclerosis, Fluid shear stress and atherosclerosis
    Gene Ensembl ENSECAG00000008126, ENSMUSG00000059552, ENSBTAG00000001069, ENSCAFG00845024647, ENSG00000141510, ENSMMUG00000008639
    Target Classification Kinase, Pathway, Checkpoint-Immuno Oncology


    About GMVC

    GDU

    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.