Explore IGFBP1/IGFBP-1 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Secreted Protein/Potential Cytokines.
This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP N-terminal domain and a thyroglobulin type-I domain. The encoded protein, mainly expressed in the liver, circulates in the plasma and binds both insulin-like growth factors (IGFs) I and II, prolonging their half-lives and altering their interaction with cell surface receptors. This protein is important in cell migration and metabolism. Low levels of this protein may be associated with impaired glucose tolerance, vascular disease and hypertension in human patients. [provided by RefSeq, Aug 2017]
| Target ID |
GM-T15048
|
| Target Name |
IGFBP1/IGFBP-1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
3484
|
| Gene ID |
100034154 (Equus caballus), 101101629 (Felis catus), 16006 (Mus musculus), 25685 (Rattus norvegicus)
282259 (Bos taurus), 3484 (Homo sapiens), 480812 (Canis lupus familiaris), 696994 (Macaca mulatta)
|
| Target Alternative Names |
AFBP,IBP-1,IBP1,IGF-BP25,IGF-binding protein 1,IGFBA,IGFBP-1,IGFBP1,Igfbp1,Insulin-like growth factor-binding protein 1,PP12,Placental protein 12 (PP12),hIGFBP-1
|
| Uniprot Accession |
P47876,P21743,P24591,P08833
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Therapeutics Target, Diagnostics Biomarker, Cytokine Target
|
| Disease |
cancer, Ovary Cancer, Non-small cell lung carcinoma
|
| Disease from KEGG |
|
| Gene Ensembl |
ENSECAG00000014889, ENSMUSG00000020429, ENSBTAG00000046768, ENSG00000146678, ENSCAFG00845011343, ENSMMUG00000059330
|
| Target Classification |
|
Pre-made viral vector of IGFBP1/IGFBP-1 cDNA Clones/ORF Plasmid
IGFBP1/IGFBP-1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3484 | Pre-made Human IGFBP1/AFBP/IBP1 siRNA oligo Duplex | 3484 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25685 | Pre-made Rat Igfbp1/IBP1/IGFBA siRNA oligo Duplex | 25685 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo16006 | Pre-made Mouse Igfbp1 siRNA oligo Duplex | 16006 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo696994 | Pre-made Cynomolgus/Rhesus macaque IGFBP1 siRNA oligo Duplex | 696994 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101101629 | Pre-made Cat/Feline IGFBP1 siRNA oligo Duplex | 101101629 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo480812 | Pre-made Dog/Canine IGFBP1 siRNA oligo Duplex | 480812 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo282259 | Pre-made Bovines/Cattle IGFBP1 siRNA oligo Duplex | 282259 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100034154 | Pre-made Equine/Horse IGFBP1/IGFBP-1 siRNA oligo Duplex | 100034154 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
IGFBP1/IGFBP-1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T15048-Ab | Human | Anti-Human IGFBP1/IGFBP-1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Diagnostic target antibody, Cytokine antibody | Detail |
| GM-Tg-rg-T15048-Ab | Rat | Anti-Rat IGFBP1/IGFBP-1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Diagnostic target antibody, Cytokine antibody | Detail |
| GM-Tg-mg-T15048-Ab | Mouse | Anti-Mouse IGFBP1/IGFBP-1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Diagnostic target antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-T15048-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque IGFBP1/IGFBP-1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Diagnostic target antibody, Cytokine antibody | Detail |
| GM-Tg-felg-T15048-Ab | Cat/Feline | Anti-Cat/Feline IGFBP1/IGFBP-1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Diagnostic target antibody, Cytokine antibody | Detail |
| GM-Tg-cang-T15048-Ab | Dog/Canine | Anti-Dog/Canine IGFBP1/IGFBP-1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Diagnostic target antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-T15048-Ab | Bovines/Cattle | Anti-Bovines/Cattle IGFBP1/IGFBP-1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Diagnostic target antibody, Cytokine antibody | Detail |
| GM-Tg-equg-T15048-Ab | Equine/Horse | Anti-Equine/Horse IGFBP1/IGFBP-1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Diagnostic target antibody, Cytokine antibody | Detail |
IGFBP1/IGFBP-1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T15048-Ag | Human | Human IGFBP1/IGFBP-1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T15048-Ag | Rat | Rat IGFBP1/IGFBP-1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T15048-Ag | Mouse | Mouse IGFBP1/IGFBP-1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T15048-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque IGFBP1/IGFBP-1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T15048-Ag | Cat/Feline | Cat/Feline IGFBP1/IGFBP-1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T15048-Ag | Dog/Canine | Dog/Canine IGFBP1/IGFBP-1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T15048-Ag | Bovines/Cattle | Bovines/Cattle IGFBP1/IGFBP-1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T15048-Ag | Equine/Horse | Equine/Horse IGFBP1/IGFBP-1 recombinant protein | Mammalian cell | Detail |
