Recombinant multi-species IGFBP1/IGFBP-1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine IGFBP1/IGFBP-1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP N-terminal domain and a thyroglobulin type-I domain. The encoded protein, mainly expressed in the liver, circulates in the plasma and binds both insulin-like growth factors (IGFs) I and II, prolonging their half-lives and altering their interaction with cell surface receptors. This protein is important in cell migration and metabolism. Low levels of this protein may be associated with impaired glucose tolerance, vascular disease and hypertension in human patients. [provided by RefSeq, Aug 2017]
The Alternative Names of target: AFBP,IBP-1,IBP1,IGF-BP25,IGF-binding protein 1,IGFBA,IGFBP-1,IGFBP1,Igfbp1,Insulin-like growth factor-binding protein 1,PP12,Placental protein 12 (PP12),hIGFBP-1

Target products collectionGo to IGFBP1/IGFBP-1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T15048-Ag-1/ GM-Tg-hg-T15048-Ag-2 Human IGFBP1/IGFBP-1 protein Human
GM-Tg-rg-T15048-Ag-1/ GM-Tg-rg-T15048-Ag-2 Rat IGFBP1/IGFBP-1 protein Rat
GM-Tg-mg-T15048-Ag-1/ GM-Tg-mg-T15048-Ag-2 Mouse IGFBP1/IGFBP-1 protein Mouse
GM-Tg-cynog-T15048-Ag-1/ GM-Tg-cynog-T15048-Ag-2 Cynomolgus/Rhesus macaque IGFBP1/IGFBP-1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T15048-Ag-1/ GM-Tg-felg-T15048-Ag-2 Feline IGFBP1/IGFBP-1 protein Feline
GM-Tg-cang-T15048-Ag-1/ GM-Tg-cang-T15048-Ag-2 Canine IGFBP1/IGFBP-1 protein Canine
GM-Tg-bovg-T15048-Ag-1/ GM-Tg-bovg-T15048-Ag-2 Bovine IGFBP1/IGFBP-1 protein Bovine
GM-Tg-equg-T15048-Ag-1/ GM-Tg-equg-T15048-Ag-2 Equine IGFBP1/IGFBP-1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T15048-Ag-1/ GM-Tg-hg-T15048-Ag-2; GM-Tg-rg-T15048-Ag-1/ GM-Tg-rg-T15048-Ag-2;
GM-Tg-mg-T15048-Ag-1/ GM-Tg-mg-T15048-Ag-2; GM-Tg-cynog-T15048-Ag-1/ GM-Tg-cynog-T15048-Ag-2;
GM-Tg-felg-T15048-Ag-1/ GM-Tg-felg-T15048-Ag-2; GM-Tg-cang-T15048-Ag-1/ GM-Tg-cang-T15048-Ag-2;
GM-Tg-bovg-T15048-Ag-1/ GM-Tg-bovg-T15048-Ag-2; GM-Tg-equg-T15048-Ag-1/ GM-Tg-equg-T15048-Ag-2
Products Name IGFBP1/IGFBP-1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name IGFBP1/IGFBP-1
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine IGFBP1/IGFBP-1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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