Explore Alpha Synuclein/SNCA gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2016]
| Target ID |
GM-T03644
|
| Target Name |
Alpha Synuclein/SNCA
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
6622
|
| Gene ID |
100053270 (Equus caballus), 101091694 (Felis catus), 20617 (Mus musculus), 282857 (Bos taurus)
29219 (Rattus norvegicus), 478478 (Canis lupus familiaris), 6622 (Homo sapiens), 706985 (Macaca mulatta)
|
| Target Alternative Names |
SNCA,Snca,NACP,alphaSYN,alpha-Syn,PD1,PARK1,PARK4
|
| Uniprot Accession |
O55042,Q3T0G8,P37377,P37840,P61143
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Diagnostics Biomarker, INN Index
|
| Disease |
|
| Disease from KEGG |
Alzheimer disease
|
| Gene Ensembl |
ENSECAG00000015766, ENSMUSG00000025889, ENSBTAG00000024957, ENSCAFG00845019506, ENSG00000145335, ENSMMUG00000012123
|
| Target Classification |
|
Pre-made viral vector of Alpha Synuclein/SNCA cDNA Clones/ORF Plasmid
Alpha Synuclein/SNCA siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo6622 | Pre-made Human SNCA/PD1/NACP siRNA oligo Duplex | 6622 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo29219 | Pre-made Rat Snca siRNA oligo Duplex | 29219 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo20617 | Pre-made Mouse Snca/NACP/alphaSYN siRNA oligo Duplex | 20617 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo706985 | Pre-made Cynomolgus/Rhesus macaque SNCA siRNA oligo Duplex | 706985 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101091694 | Pre-made Cat/Feline SNCA siRNA oligo Duplex | 101091694 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo478478 | Pre-made Dog/Canine SNCA siRNA oligo Duplex | 478478 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo282857 | Pre-made Bovines/Cattle SNCA siRNA oligo Duplex | 282857 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100053270 | Pre-made Equine/Horse SNCA siRNA oligo Duplex | 100053270 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
Alpha Synuclein/SNCA antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T03644-Ab | Human | Anti-Human Alpha Synuclein/SNCA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Diagnostic target antibody | Detail |
| GM-Tg-rg-T03644-Ab | Rat | Anti-Rat Alpha Synuclein/SNCA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Diagnostic target antibody | Detail |
| GM-Tg-mg-T03644-Ab | Mouse | Anti-Mouse Alpha Synuclein/SNCA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Diagnostic target antibody | Detail |
| GM-Tg-cynog-T03644-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque Alpha Synuclein/SNCA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Diagnostic target antibody | Detail |
| GM-Tg-felg-T03644-Ab | Cat/Feline | Anti-Cat/Feline Alpha Synuclein/SNCA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Diagnostic target antibody | Detail |
| GM-Tg-cang-T03644-Ab | Dog/Canine | Anti-Dog/Canine Alpha Synuclein/SNCA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Diagnostic target antibody | Detail |
| GM-Tg-bovg-T03644-Ab | Bovines/Cattle | Anti-Bovines/Cattle Alpha Synuclein/SNCA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Diagnostic target antibody | Detail |
| GM-Tg-equg-T03644-Ab | Equine/Horse | Anti-Equine/Horse Alpha Synuclein/SNCA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Diagnostic target antibody | Detail |
Alpha Synuclein/SNCA VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T03644-Ag | Human | Human Alpha Synuclein/SNCA VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T03644-Ag | Rat | Rat Alpha Synuclein/SNCA VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T03644-Ag | Mouse | Mouse Alpha Synuclein/SNCA VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T03644-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque Alpha Synuclein/SNCA VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T03644-Ag | Cat/Feline | Cat/Feline Alpha Synuclein/SNCA VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T03644-Ag | Dog/Canine | Dog/Canine Alpha Synuclein/SNCA VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T03644-Ag | Bovines/Cattle | Bovines/Cattle Alpha Synuclein/SNCA VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T03644-Ag | Equine/Horse | Equine/Horse Alpha Synuclein/SNCA VLP (virus-like particle) | HEK293 | Products Developing |
