Explore TNFRSF6B gene products and cross-species
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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Secreted Protein/Potential Cytokines.
This gene belongs to the tumor necrosis factor receptor superfamily. The encoded protein is postulated to play a regulatory role in suppressing FasL- and LIGHT-mediated cell death. It acts as a decoy receptor that competes with death receptors for ligand binding. Over-expression of this gene has been noted in gastrointestinal tract tumors. Read-through transcription into this gene from the neighboring upstream gene, which encodes regulator of telomere elongation helicase 1 (RTEL1), generates a non-coding transcript. [provided by RefSeq, Feb 2011]
| Target ID |
GM-SE1344
|
| Target Name |
TNFRSF6B
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
8771
|
| Gene ID |
102899242 (Felis catus), 111770055 (Equus caballus), 114669829 (Macaca mulatta), 119865736 (Canis lupus familiaris)
789154 (Bos taurus), 8771 (Homo sapiens)
|
| Target Alternative Names |
DCR3,DJ583P15.1.1,Decoy receptor 3 (DcR3),Decoy receptor for Fas ligand,M68,M68E,TNFRSF6B,TR6,Tumor necrosis factor receptor superfamily member 6B
|
| Uniprot Accession |
O95407
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Cytokine Target
|
| Disease |
cancer, Colon Cancer
|
| Disease from KEGG |
Cytokine-cytokine receptor interaction
|
| Gene Ensembl |
ENSECAG00000032390, ENSMMUG00000045470, ENSCAFG00845018187, ENSBTAG00000007498, ENSG00000243509
|
Pre-made viral vector of TNFRSF6B cDNA Clones/ORF Plasmid
TNFRSF6B siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo8771 | Pre-made Human TNFRSF6B/M68/TR6 siRNA oligo Duplex | 8771 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo114669829 | Pre-made Cynomolgus/Rhesus macaque TNFRSF6B siRNA oligo Duplex | 114669829 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo102899242 | Pre-made Cat/Feline TNFRSF6B siRNA oligo Duplex | 102899242 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo119865736 | Pre-made Dog/Canine TNFRSF6B siRNA oligo Duplex | 119865736 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo789154 | Pre-made Bovines/Cattle TNFRSF6B siRNA oligo Duplex | 789154 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo111770055 | Pre-made Equine/Horse TNFRSF6B siRNA oligo Duplex | 111770055 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
TNFRSF6B antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-SE1344-Ab | Human | Anti-Human TNFRSF6B monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-SE1344-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque TNFRSF6B monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-felg-SE1344-Ab | Cat/Feline | Anti-Cat/Feline TNFRSF6B monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-cang-SE1344-Ab | Dog/Canine | Anti-Dog/Canine TNFRSF6B monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-SE1344-Ab | Bovines/Cattle | Anti-Bovines/Cattle TNFRSF6B monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-equg-SE1344-Ab | Equine/Horse | Anti-Equine/Horse TNFRSF6B monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
TNFRSF6B recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-SE1344-Ag | Human | Human TNFRSF6B recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-SE1344-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque TNFRSF6B recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-SE1344-Ag | Cat/Feline | Cat/Feline TNFRSF6B recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-SE1344-Ag | Dog/Canine | Dog/Canine TNFRSF6B recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-SE1344-Ag | Bovines/Cattle | Bovines/Cattle TNFRSF6B recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-SE1344-Ag | Equine/Horse | Equine/Horse TNFRSF6B recombinant protein | Mammalian cell | Detail |
