Recombinant multi-species TNFRSF6B protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TNFRSF6B protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene belongs to the tumor necrosis factor receptor superfamily. The encoded protein is postulated to play a regulatory role in suppressing FasL- and LIGHT-mediated cell death. It acts as a decoy receptor that competes with death receptors for ligand binding. Over-expression of this gene has been noted in gastrointestinal tract tumors. Read-through transcription into this gene from the neighboring upstream gene, which encodes regulator of telomere elongation helicase 1 (RTEL1), generates a non-coding transcript. [provided by RefSeq, Feb 2011]
The Alternative Names of target: DCR3,DJ583P15.1.1,Decoy receptor 3 (DcR3),Decoy receptor for Fas ligand,M68,M68E,TNFRSF6B,TR6,Tumor necrosis factor receptor superfamily member 6B

Target products collectionGo to TNFRSF6B products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-SE1344-Ag-1/ GM-Tg-hg-SE1344-Ag-2 Human TNFRSF6B protein Human
GM-Tg-rg-SE1344-Ag-1/ GM-Tg-rg-SE1344-Ag-2 Rat TNFRSF6B protein Rat
GM-Tg-mg-SE1344-Ag-1/ GM-Tg-mg-SE1344-Ag-2 Mouse TNFRSF6B protein Mouse
GM-Tg-cynog-SE1344-Ag-1/ GM-Tg-cynog-SE1344-Ag-2 Cynomolgus/Rhesus macaque TNFRSF6B protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-SE1344-Ag-1/ GM-Tg-felg-SE1344-Ag-2 Feline TNFRSF6B protein Feline
GM-Tg-cang-SE1344-Ag-1/ GM-Tg-cang-SE1344-Ag-2 Canine TNFRSF6B protein Canine
GM-Tg-bovg-SE1344-Ag-1/ GM-Tg-bovg-SE1344-Ag-2 Bovine TNFRSF6B protein Bovine
GM-Tg-equg-SE1344-Ag-1/ GM-Tg-equg-SE1344-Ag-2 Equine TNFRSF6B protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-SE1344-Ag-1/ GM-Tg-hg-SE1344-Ag-2; GM-Tg-rg-SE1344-Ag-1/ GM-Tg-rg-SE1344-Ag-2;
GM-Tg-mg-SE1344-Ag-1/ GM-Tg-mg-SE1344-Ag-2; GM-Tg-cynog-SE1344-Ag-1/ GM-Tg-cynog-SE1344-Ag-2;
GM-Tg-felg-SE1344-Ag-1/ GM-Tg-felg-SE1344-Ag-2; GM-Tg-cang-SE1344-Ag-1/ GM-Tg-cang-SE1344-Ag-2;
GM-Tg-bovg-SE1344-Ag-1/ GM-Tg-bovg-SE1344-Ag-2; GM-Tg-equg-SE1344-Ag-1/ GM-Tg-equg-SE1344-Ag-2
Products Name TNFRSF6B protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name TNFRSF6B
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TNFRSF6B protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.