TIMP2 Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore TIMP2 gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Secreted Protein/Potential Cytokines.
This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix. [provided by RefSeq, Jul 2008]

Target ID GM-SE1338
Target Name TIMP2
Gene Group ldentifer
(Target Gene ID in Homo species)
7077
Gene ID 100034134 (Equus caballus), 101083125 (Felis catus), 21858 (Mus musculus), 282093 (Bos taurus)
29543 (Rattus norvegicus), 403633 (Canis lupus familiaris), 574357 (Macaca mulatta), 7077 (Homo sapiens)
Target Alternative Names CSC-21K,D11Bwg1104e,DDC8,Metalloproteinase inhibitor 2,TIMP-2,TIMP2,Timp-2,Timp2,Tissue inhibitor of metalloproteinases 2 (TIMP-2)
Uniprot Accession O77717,P25785,P16368,P30121,Q9TTY1,P16035
Protein Sub-location Secreted Protein/Potential Cytokines
Disease cancer, Acute kidney failure, Dent disease, Malignant neoplasm of bladder
Gene Ensembl ENSECAG00000060149, ENSMUSG00000017466, ENSBTAG00000010899, ENSG00000035862


Pre-made viral vector of TIMP2 cDNA Clones/ORF Plasmid

Cat No.Product NameNMIDGeneIDSpeciesTypeMarkerFusion TagPromoterDetail
pGMLP002009Human TIMP2/CSC-21K/DDC8 Lentivirus plasmidNM_003255.47077HumanLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
vGMLP002009Human TIMP2/CSC-21K/DDC8 Lentivirus particleNM_003255.47077HumanLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail
pGMAAV001303Mouse Timp2/D11Bwg1104e/Timp-2 Adeno-associate virus(AAV) plasmidNM_011594.321858MouseAdeno-associate virus(AAV) plasmidNull3xflag (C-Terminal)CMVDetail
pGMLPm000991Mouse Timp2/D11Bwg1104e/Timp-2 Lentivirus plasmidNM_01159421858MouseLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
pGMPC000464Mouse Timp2/D11Bwg1104e/TIMP Mammalian (Non-Viral Vector) plasmidNM_01159421858MouseMammalian (Non-Viral Vector) plasmidNull3xflag (C-Terminal)CMVDetail
vGMAAV001303Mouse Timp2/D11Bwg1104e/Timp-2 Adeno-associate virus(AAV) particleNM_011594.321858MouseAdeno-associate virus(AAV) particleNull3xflag (C-Terminal)CMVDetail
vGMLPm000991Mouse Timp2/D11Bwg1104e/Timp-2 Lentivirus particleNM_01159421858MouseLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail


TIMP2 siRNA/miRNA/oligo for RNA interfence (RNAi)

Cat No.Product NameGeneIDSpeciesGradeDetail
pGMoligo7077Pre-made Human TIMP2/DDC8/CSC-21K siRNA oligo Duplex7077HumanIn-vitro grade; in-vivo gradeDetail
pGMoligo29543Pre-made Rat Timp2 siRNA oligo Duplex29543RatIn-vitro grade; in-vivo gradeDetail
pGMoligo21858Pre-made Mouse Timp2/Timp-2/D11Bwg1104e siRNA oligo Duplex21858MouseIn-vitro grade; in-vivo gradeDetail
pGMoligo574357Pre-made Cynomolgus/Rhesus macaque TIMP2/TIMP-2 siRNA oligo Duplex574357Cynomolgus/Rhesus macaqueIn-vitro grade; in-vivo gradeDetail
pGMoligo101083125Pre-made Cat/Feline TIMP2 siRNA oligo Duplex101083125Cat/FelineIn-vitro grade; in-vivo gradeDetail
pGMoligo403633Pre-made Dog/Canine TIMP2 siRNA oligo Duplex403633Dog/CanineIn-vitro grade; in-vivo gradeDetail
pGMoligo282093Pre-made Bovines/Cattle TIMP2 siRNA oligo Duplex282093Bovines/CattleIn-vitro grade; in-vivo gradeDetail
pGMoligo100034134Pre-made Equine/Horse TIMP2/TIMP-2 siRNA oligo Duplex100034134Equine/HorseIn-vitro grade; in-vivo gradeDetail


TIMP2 antibody/GMab

Cat No.SpeciesAntibody NameFormatClassified by tagDetail
GM-Tg-hg-SE1338-AbHumanAnti-Human TIMP2 monoclonal antibodymabFACS/Biofunctional AntibodyDetail
GM-Tg-rg-SE1338-AbRatAnti-Rat TIMP2 monoclonal antibodymabFACS/Biofunctional AntibodyDetail
GM-Tg-mg-SE1338-AbMouseAnti-Mouse TIMP2 monoclonal antibodymabFACS/Biofunctional AntibodyDetail
GM-Tg-cynog-SE1338-AbCynomolgus/Rhesus macaqueAnti-Cynomolgus/Rhesus macaque TIMP2 monoclonal antibodymabFACS/Biofunctional AntibodyDetail
GM-Tg-felg-SE1338-AbCat/FelineAnti-Cat/Feline TIMP2 monoclonal antibodymabFACS/Biofunctional AntibodyDetail
GM-Tg-cang-SE1338-AbDog/CanineAnti-Dog/Canine TIMP2 monoclonal antibodymabFACS/Biofunctional AntibodyDetail
GM-Tg-bovg-SE1338-AbBovines/CattleAnti-Bovines/Cattle TIMP2 monoclonal antibodymabFACS/Biofunctional AntibodyDetail
GM-Tg-equg-SE1338-AbEquine/HorseAnti-Equine/Horse TIMP2 monoclonal antibodymabFACS/Biofunctional AntibodyDetail


TIMP2 recombinant protein

Cat No.SpeciesAntigen NameExpression PlatformDetail
GM-Tg-hg-SE1338-AgHumanHuman TIMP2 recombinant proteinMammalian cellDetail
GM-Tg-rg-SE1338-AgRatRat TIMP2 recombinant proteinMammalian cellDetail
GM-Tg-mg-SE1338-AgMouseMouse TIMP2 recombinant proteinMammalian cellDetail
GM-Tg-cynog-SE1338-AgCynomolgus/Rhesus macaqueCynomolgus/Rhesus macaque TIMP2 recombinant proteinMammalian cellDetail
GM-Tg-felg-SE1338-AgCat/FelineCat/Feline TIMP2 recombinant proteinMammalian cellDetail
GM-Tg-cang-SE1338-AgDog/CanineDog/Canine TIMP2 recombinant proteinMammalian cellDetail
GM-Tg-bovg-SE1338-AgBovines/CattleBovines/Cattle TIMP2 recombinant proteinMammalian cellDetail
GM-Tg-equg-SE1338-AgEquine/HorseEquine/Horse TIMP2 recombinant proteinMammalian cellDetail