Recombinant multi-species TIMP2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TIMP2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix. [provided by RefSeq, Jul 2008]
The Alternative Names of target: CSC-21K,D11Bwg1104e,DDC8,Metalloproteinase inhibitor 2,TIMP-2,TIMP2,Timp-2,Timp2,Tissue inhibitor of metalloproteinases 2 (TIMP-2)

Target products collectionGo to TIMP2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-SE1338-Ag-1/ GM-Tg-hg-SE1338-Ag-2 Human TIMP2 protein Human
GM-Tg-rg-SE1338-Ag-1/ GM-Tg-rg-SE1338-Ag-2 Rat TIMP2 protein Rat
GM-Tg-mg-SE1338-Ag-1/ GM-Tg-mg-SE1338-Ag-2 Mouse TIMP2 protein Mouse
GM-Tg-cynog-SE1338-Ag-1/ GM-Tg-cynog-SE1338-Ag-2 Cynomolgus/Rhesus macaque TIMP2 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-SE1338-Ag-1/ GM-Tg-felg-SE1338-Ag-2 Feline TIMP2 protein Feline
GM-Tg-cang-SE1338-Ag-1/ GM-Tg-cang-SE1338-Ag-2 Canine TIMP2 protein Canine
GM-Tg-bovg-SE1338-Ag-1/ GM-Tg-bovg-SE1338-Ag-2 Bovine TIMP2 protein Bovine
GM-Tg-equg-SE1338-Ag-1/ GM-Tg-equg-SE1338-Ag-2 Equine TIMP2 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-SE1338-Ag-1/ GM-Tg-hg-SE1338-Ag-2; GM-Tg-rg-SE1338-Ag-1/ GM-Tg-rg-SE1338-Ag-2;
GM-Tg-mg-SE1338-Ag-1/ GM-Tg-mg-SE1338-Ag-2; GM-Tg-cynog-SE1338-Ag-1/ GM-Tg-cynog-SE1338-Ag-2;
GM-Tg-felg-SE1338-Ag-1/ GM-Tg-felg-SE1338-Ag-2; GM-Tg-cang-SE1338-Ag-1/ GM-Tg-cang-SE1338-Ag-2;
GM-Tg-bovg-SE1338-Ag-1/ GM-Tg-bovg-SE1338-Ag-2; GM-Tg-equg-SE1338-Ag-1/ GM-Tg-equg-SE1338-Ag-2
Products Name TIMP2 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name TIMP2
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TIMP2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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