Explore PTHLH gene products and cross-species
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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Secreted Protein/Potential Cytokines.
The protein encoded by this gene is a member of the parathyroid hormone family. This hormone, via its receptor, PTHR1, regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. It is responsible for most cases of humoral hypercalcemia of malignancy, and mutations in this gene are associated with brachydactyly type E2 (BDE2). Alternatively spliced transcript variants have been found for this gene. There is also evidence for alternative translation initiation from non-AUG (CUG and GUG) start sites, downstream of the initiator AUG codon, resulting in nuclear forms of this hormone. [provided by RefSeq, Nov 2013]
| Target ID |
GM-SE1230
|
| Target Name |
PTHLH
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
5744
|
| Gene ID |
100033979 (Equus caballus), 19227 (Mus musculus), 24695 (Rattus norvegicus), 286767 (Bos taurus) 403987 (Canis lupus familiaris), 554222 (Felis catus), 5744 (Homo sapiens), 710295 (Macaca mulatta)
|
| Target Alternative Names |
BDE2,HHM,PLP,PTH-like,PTH-rP,PTHLH,PTHR,PTHRP,PTHrP,Parathyroid hormone-like protein (PLP),Parathyroid hormone-related protein,Pthlh,Pthrp
|
| Uniprot Accession |
Q9GMB7,P22858,P13085,P58073,P52211,P12272
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Disease |
cancer, Lung cancer
|
| Disease from KEGG |
Parathyroid hormone synthesis, secretion and action
|
| Gene Ensembl |
ENSECAG00000014708, ENSMUSG00000048776, ENSBTAG00000006538, ENSCAFG00845022996, ENSG00000087494, ENSMMUG00000010531
|
Pre-made viral vector of PTHLH cDNA Clones/ORF Plasmid
PTHLH siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo5744 | Pre-made Human PTHLH/HHM/PLP siRNA oligo Duplex | 5744 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo24695 | Pre-made Rat Pthlh/PLP siRNA oligo Duplex | 24695 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo19227 | Pre-made Mouse Pthlh/PLP/Pthrp siRNA oligo Duplex | 19227 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo710295 | Pre-made Cynomolgus/Rhesus macaque PTHLH siRNA oligo Duplex | 710295 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo554222 | Pre-made Cat/Feline PTHLH/PTHrP siRNA oligo Duplex | 554222 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo403987 | Pre-made Dog/Canine PTHLH/PTHRP siRNA oligo Duplex | 403987 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo286767 | Pre-made Bovines/Cattle PTHLH/PTHrP siRNA oligo Duplex | 286767 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100033979 | Pre-made Equine/Horse PTHLH/PTHrP siRNA oligo Duplex | 100033979 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
PTHLH antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-SE1230-Ab | Human | Anti-Human PTHLH monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-SE1230-Ab | Rat | Anti-Rat PTHLH monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-SE1230-Ab | Mouse | Anti-Mouse PTHLH monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-SE1230-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque PTHLH monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-SE1230-Ab | Cat/Feline | Anti-Cat/Feline PTHLH monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-SE1230-Ab | Dog/Canine | Anti-Dog/Canine PTHLH monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-SE1230-Ab | Bovines/Cattle | Anti-Bovines/Cattle PTHLH monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-SE1230-Ab | Equine/Horse | Anti-Equine/Horse PTHLH monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
PTHLH recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-SE1230-Ag | Human | Human PTHLH recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-SE1230-Ag | Rat | Rat PTHLH recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-SE1230-Ag | Mouse | Mouse PTHLH recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-SE1230-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque PTHLH recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-SE1230-Ag | Cat/Feline | Cat/Feline PTHLH recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-SE1230-Ag | Dog/Canine | Dog/Canine PTHLH recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-SE1230-Ag | Bovines/Cattle | Bovines/Cattle PTHLH recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-SE1230-Ag | Equine/Horse | Equine/Horse PTHLH recombinant protein | Mammalian cell | Detail |