Recombinant multi-species PTHLH protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PTHLH protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a member of the parathyroid hormone family. This hormone, via its receptor, PTHR1, regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. It is responsible for most cases of humoral hypercalcemia of malignancy, and mutations in this gene are associated with brachydactyly type E2 (BDE2). Alternatively spliced transcript variants have been found for this gene. There is also evidence for alternative translation initiation from non-AUG (CUG and GUG) start sites, downstream of the initiator AUG codon, resulting in nuclear forms of this hormone. [provided by RefSeq, Nov 2013]
The Alternative Names of target: BDE2,HHM,PLP,PTH-like,PTH-rP,PTHLH,PTHR,PTHRP,PTHrP,Parathyroid hormone-like protein (PLP),Parathyroid hormone-related protein,Pthlh,Pthrp
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE1230-Ag-1/ GM-Tg-hg-SE1230-Ag-2 | Human PTHLH protein | Human |
| GM-Tg-rg-SE1230-Ag-1/ GM-Tg-rg-SE1230-Ag-2 | Rat PTHLH protein | Rat |
| GM-Tg-mg-SE1230-Ag-1/ GM-Tg-mg-SE1230-Ag-2 | Mouse PTHLH protein | Mouse |
| GM-Tg-cynog-SE1230-Ag-1/ GM-Tg-cynog-SE1230-Ag-2 | Cynomolgus/Rhesus macaque PTHLH protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE1230-Ag-1/ GM-Tg-felg-SE1230-Ag-2 | Feline PTHLH protein | Feline |
| GM-Tg-cang-SE1230-Ag-1/ GM-Tg-cang-SE1230-Ag-2 | Canine PTHLH protein | Canine |
| GM-Tg-bovg-SE1230-Ag-1/ GM-Tg-bovg-SE1230-Ag-2 | Bovine PTHLH protein | Bovine |
| GM-Tg-equg-SE1230-Ag-1/ GM-Tg-equg-SE1230-Ag-2 | Equine PTHLH protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-SE1230-Ag-1/ GM-Tg-hg-SE1230-Ag-2;
GM-Tg-rg-SE1230-Ag-1/ GM-Tg-rg-SE1230-Ag-2;
GM-Tg-mg-SE1230-Ag-1/ GM-Tg-mg-SE1230-Ag-2; GM-Tg-cynog-SE1230-Ag-1/ GM-Tg-cynog-SE1230-Ag-2; GM-Tg-felg-SE1230-Ag-1/ GM-Tg-felg-SE1230-Ag-2; GM-Tg-cang-SE1230-Ag-1/ GM-Tg-cang-SE1230-Ag-2; GM-Tg-bovg-SE1230-Ag-1/ GM-Tg-bovg-SE1230-Ag-2; GM-Tg-equg-SE1230-Ag-1/ GM-Tg-equg-SE1230-Ag-2 |
| Products Name | PTHLH protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | PTHLH |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PTHLH protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
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GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
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characterized by high binding affinity,
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Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
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myriad domains of biological drug
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innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.